• 1863 Citations
  • 26 h-Index
20002020

Research output per year

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Research Output

2020

Aberrant structure of fibrillar collagen and elevated levels of advanced glycation end products typify delayed fracture healing in the diet-induced obesity mouse model

Khajuria, D. K., Soliman, M., Elfar, J. C., Lewis, G. S., Abraham, T., Kamal, F. & Elbarbary, R. A., Aug 2020, In : Bone. 137, 115436.

Research output: Contribution to journalArticle

Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells

Kim, Y. S., Gupta Vallur, P., Jones, V. M., Worley, B. L., Shimko, S., Shin, D. H., Crawford, L. T. C., Chen, C. W., Aird, K. M., Abraham, T., Shepherd, T. G., Warrick, J. I., Lee, N. Y., Phaeton, R., Mythreye, K. & Hempel, N., Feb 20 2020, In : Oncogene. 39, 8, p. 1619-1633 15 p.

Research output: Contribution to journalArticle

Structural remodeling of fibrillar collagens in posterior tibial tendinopathy in three dimensional space identified using multiphoton and second harmonic generation imaging

Abraham, T., Koob, K. R., Carkaci-Salli, N. & Aydogan, U., Jan 1 2020, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVIII. Farkas, D. L. & Tarnok, A. (eds.). SPIE, 112431R. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11243).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2019

A peptide derived from melanotransferrin delivers a protein-based interleukin 1 receptor antagonist across the BBB and ameliorates neuropathic pain in a preclinical model

Thom, G., Tian, M. M., Hatcher, J. P., Rodrigo, N., Burrell, M., Gurrell, I., Vitalis, T. Z., Abraham, T., Jefferies, W. A., Webster, C. I. & Gabathuler, R., Oct 1 2019, In : Journal of Cerebral Blood Flow and Metabolism. 39, 10, p. 2074-2088 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

Educating and training biomedical researchers in biophotonics and advanced light microscopy methods

Abraham, T., Jan 1 2019, Fifteenth Conference on Education and Training in Optics and Photonics, ETOP 2019. Poulin-Girard, A-S. & Shaw, J. A. (eds.). SPIE, 1114326. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 11143).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access

Extracellular vesicle-dependent effect of RNA-binding protein IGF2BP1 on melanoma metastasis

Ghoshal, A., Rodrigues, L. C., Gowda, C. P., Elcheva, I. A., Liu, Z., Abraham, T. & Spiegelman, V. S., May 23 2019, In : Oncogene. 38, 21, p. 4182-4196 15 p.

Research output: Contribution to journalArticle

3 Scopus citations
Open Access

Multiphoton and harmonic generation imaging methods enable direct visualization of drug nanoparticle carriers in conjunction with vasculature in fibrotic prostate tumor mouse model

Abraham, T., Clawson, G. A., McGovern, C. O., Edris, W., Tang, X., Adair, J. H. & Matters, G. L., Jan 1 2019, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVII. Tarnok, A., Leary, J. F. & Farkas, D. L. (eds.). SPIE, 108811T. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10881).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

VPS37A directs ESCRT recruitment for phagophore closure

Takahashi, Y., Liang, X., Hattori, T., Tang, Z., He, H., Chen, H., Liu, X., Abraham, T., Imamura-Kawasawa, Y., Buchkovich, N. J., Young, M. M. & Wang, H. G., Oct 7 2019, In : The Journal of cell biology. 218, 10, p. 3336-3354 19 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations
2018

An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure

Takahashi, Y., He, H., Tang, Z., Hattori, T., Liu, Y., Young, M. M., Serfass, J. M., Chen, L., Gebru, M., Chen, C., Wills, C. A., Atkinson, J. M., Chen, H., Abraham, T. & Wang, H. G., Dec 1 2018, In : Nature communications. 9, 1, 2855.

Research output: Contribution to journalArticle

47 Scopus citations

Tumor-promoting effects of pancreatic cancer cell exosomes on THP-1-derived macrophages

Linton, S. S., Abraham, T., Liao, J., Clawson, G. A., Butler, P. J., Fox, T., Kester, M. & Matters, G. L., Nov 2018, In : PloS one. 13, 11, e0206759.

Research output: Contribution to journalArticle

9 Scopus citations
2017

A Cholecystokinin B Receptor-Specific DNA Aptamer for Targeting Pancreatic Ductal Adenocarcinoma

Clawson, G. A., Abraham, T., Pan, W., Tang, X., Linton, S. S., McGovern, C. O., Loc, W. S., Smith, J. P., Butler, P. J., Kester, M., Adair, J. H. & Matters, G. L., Feb 2017, In : Nucleic Acid Therapeutics. 27, 1, p. 23-35 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

A novel dual inhibitor of microtubule and Bruton's tyrosine kinase inhibits survival of multiple myeloma and osteoclastogenesis

Pandey, M. K., Gowda, K., Sung, S. S., Abraham, T., Budak-Alpdogan, T., Talamo, G., Dovat, S. & Amin, S., Sep 2017, In : Experimental Hematology. 53, p. 31-42 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Domain interaction studies of herpes simplex virus 1 tegument protein UL16 reveal its interaction with mitochondria

Chadha, P., Sarfo, A., Zhang, D., Abraham, T., Carmichael, J., Han, J. & Wills, J. W., Jan 1 2017, In : Journal of virology. 91, 2, e01995-16.

Research output: Contribution to journalArticle

5 Scopus citations

Effective encapsulation and biological activity of phosphorylated chemotherapeutics in calcium phosphosilicate nanoparticles for the treatment of pancreatic cancer

Loc, W. S., Linton, S. S., Wilczynski, Z. R., Matters, G., McGovern, C. O., Abraham, T., Fox, T., Gigliotti, C. M., Tang, X., Tabakovic, A., Martin, J. A., Clawson, G., Smith, J. P., Butler, P. J., Kester, M. & Adair, J. H., Oct 2017, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 13, 7, p. 2313-2324 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

PIGN gene expression aberration is associated with genomic instability and leukemic progression in acute myeloid leukemia with myelodysplastic features

Teye, E. K., Sido, A., Xin, P., Finnberg, N. K., Gokare, P., Kawasawa, Y. I., Salzberg, A. C., Shimko, S., Bayerl, M., Ehmann, W. C., Claxton, D. F., Rybka, W. B., Drabick, J. J., Wang, H. G., Abraham, T., El-Deiry, W. S., Brodsky, R. A., J.Hohl, R. & Pu, J. J., Jan 1 2017, In : Oncotarget. 8, 18, p. 29887-29905 19 p.

Research output: Contribution to journalArticle

3 Scopus citations

SH3GLB2/endophilin B2 regulates lung homeostasis and recovery from severe influenza A virus infection

Fino, K. K., Yang, L., Silveyra, P., Hu, S., Umstead, T. M., Diangelo, S., Halstead, E. S., Cooper, T. K., Abraham, T., Takahashi, Y., Zhou, Z., Wang, H. G. & Chroneos, Z. C., Dec 1 2017, In : Scientific reports. 7, 1, 7262.

Research output: Contribution to journalArticle

4 Scopus citations

"Stealth dissemination" of macrophage-tumor cell fusions cultured from blood of patients with pancreatic ductal adenocarcinoma

Clawson, G. A., Matters, G. L., Xin, P., McGovern, C., Wafula, E., DePamphilis, C., Meckley, M., Wong, J., Stewart, L., D’Jamoos, C., Altman, N., Kawasawa, Y. I., Du, Z., Honaas, L. & Abraham, T., Sep 2017, In : PloS one. 12, 9, e0184451.

Research output: Contribution to journalArticle

8 Scopus citations
2016

Depletion of the human ion channel TRPM2 in neuroblastoma demonstrates its key role in cell survival through modulation of mitochondrial reactive oxygen species and bioenergetics

Bao, L., Chen, S. J., Conrad, K., Keefer, K., Abraham, T., Lee, J. P., Wang, J. F., Zhang, X. Q., Hirschler-Laszkiewicz, I., Wang, H. G., Dovat, S., Gans, B., Madesh, M., Cheung, J. Y. & Miller, B. A., Nov 18 2016, In : Journal of Biological Chemistry. 291, 47, p. 24449-24464 16 p.

Research output: Contribution to journalArticle

26 Scopus citations

The Bif-1-Dynamin 2 membrane fission machinery regulates Atg9-containing vesicle generation at the Rab11-positive reservoirs

Takahashi, Y., Tsotakos, N., Liu, Y., Young, M. M., Serfass, J., Tang, Z., Abraham, T. & Wang, H. G., Apr 12 2016, In : Oncotarget. 7, 15, p. 20855-20868 14 p.

Research output: Contribution to journalArticle

30 Scopus citations
2015

B cell-intrinsic CD84 and Ly108 maintain germinal center B cell tolerance

Wong, E. B., Soni, C., Chan, A. Y., Domeier, P. P., Shwetank, Abraham, T., Limaye, N., Khan, T. N., Elias, M. J., Chodisetti, S. B., Wakeland, E. K. & Rahman, Z. S. M., May 1 2015, In : Journal of Immunology. 194, 9, p. 4130-4143 14 p.

Research output: Contribution to journalArticle

23 Scopus citations
28 Scopus citations

Response to Letter Regarding Article, "contribution of intimal smooth muscle cells to cholesterol accumulation and macrophage-like cells in human atherosclerosis"

Francis, G. A., Allahverdian, S., Cheroudi, A. C., Abraham, T. & McManus, B. M., Jan 1 2015, In : Circulation. 131, 3, p. e25

Research output: Contribution to journalLetter

Simple experimental methods for determining the apparent focal shift in a microscope system

Bratton, B. P., Shaevitz, J. W. & Abraham, T., Aug 13 2015, In : PloS one. 10, 8, e0134616.

Research output: Contribution to journalArticle

7 Scopus citations

Versican localizes to the nucleus in proliferating mesenchymal cells

Carthy, J. M., Abraham, T., Meredith, A. J., Boroomand, S. & McManus, B. M., Nov 1 2015, In : Cardiovascular Pathology. 24, 6, p. 368-374 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Versican V1 overexpression induces a myofibroblast-like phenotype in cultured fibroblasts

Carthy, J. M., Meredith, A. J., Boroomand, S., Abraham, T., Luo, Z., Knight, D. & McManus, B. M., Jul 15 2015, In : PloS one. 10, 7, e0133056.

Research output: Contribution to journalArticle

12 Scopus citations

Vitronectin expression in the airways of subjects with asthma and chronic obstructive pulmonary disease

Salazar-Peláez, L. M., Abraham, T., Herrera, A. M., Correa, M. A., Ortega, J. E., Paré, P. D. & Seow, C. Y., Mar 13 2015, In : PloS one. 10, 3, e0119717.

Research output: Contribution to journalArticle

11 Scopus citations
2014

A splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2α

Chen, S. J., Hoffman, N. E., Shanmughapriy, S., Bao, L., Keefer, K., Conrad, K., Merali, S., Takahashi, Y., Abraham, T., Hirschler-Laszkiewicz, I., Wang, J. F., Zhang, X. Q., Song, J., Barrero, C., Shi, Y., Kawasawa, Y. I., Bayerl, M., Sun, T., Barbour, M., Wang, H. G. & 3 others, Madesh, M., Cheung, J. Y. & Miller, B. A., Jan 1 2014, In : Journal of Biological Chemistry. 289, 52, p. 36284-36302 19 p.

Research output: Contribution to journalArticle

47 Scopus citations

Contribution of intimal smooth muscle cells to cholesterol accumulation and macrophage-like cells in human atherosclerosis

Allahverdian, S., Chehroudi, A. C., McManus, B. M., Abraham, T. & Francis, G. A., Jan 1 2014, In : Circulation. 129, 15, p. 1551-1559 9 p.

Research output: Contribution to journalArticle

219 Scopus citations

Cryo-imaging of inflated frozen human lung sections at -60°c using multiphoton and harmonic generation microscopy

Abraham, T. & Hogg, J. C., Aug 1 2014, In : Microscopy and Microanalysis. 20, 3, p. 1348-1349 2 p.

Research output: Contribution to journalConference article

Podocalyxin regulates murine lung vascular permeability by altering endothelial cell adhesion

Debruin, E. J., Hughes, M. R., Sina, C., Liu, A., Cait, J., Jian, Z., Lopez, M., Lo, B., Abraham, T. & McNagny, K. M., Oct 10 2014, In : PloS one. 9, 10, e108881.

Research output: Contribution to journalArticle

20 Scopus citations

Structure-activity relationships of the antimicrobial peptide gramicidin S and its analogs: Aqueous solubility, self-association, conformation, antimicrobial activity and interaction with model lipid membranes

Abraham, T., Prenner, E. J., Lewis, R. N. A. H., Mant, C. T., Keller, S., Hodges, R. S. & McElhaney, R. N., May 2014, In : Biochimica et Biophysica Acta - Biomembranes. 1838, 5, p. 1420-1429 10 p.

Research output: Contribution to journalArticle

21 Scopus citations
2013

Increased mast cell numbers in a calcaneal tendon overuse model

Pingel, J., Wienecke, J., Kongsgaard, M., Behzad, H., Abraham, T., Langberg, H. & Scott, A., Dec 2013, In : Scandinavian Journal of Medicine and Science in Sports. 23, 6, p. e353-e360

Research output: Contribution to journalArticle

24 Scopus citations

Multiphoton microscopy based cryo-imaging of inflated frozen human lung sections at -60OC in healthy and COPD lungs

Abraham, T., Kayra, D., Zhang, A., Suzuki, M., McDonagh, J., Elliott, W. M., Cooper, J. D. & Hogg, J. C., Jun 12 2013, Multiphoton Microscopy in the Biomedical Sciences XIII. 85881Q. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 8588).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2012

miR-33a modulates ABCA1 expression, cholesterol accumulation, and insulin secretion in pancreatic islets

Wijesekara, N., Zhang, L. H., Kang, M. H., Abraham, T., Bhattacharjee, A., Warnock, G. L., Verchere, C. B. & Hayden, M. R., Mar 1 2012, In : Diabetes. 61, 3, p. 653-658 6 p.

Research output: Contribution to journalArticle

89 Scopus citations

Proteinase inhibitor 9 is reduced in human atherosclerotic lesion development

Hendel, A., Cooper, D., Abraham, T., Zhao, H., Allard, M. F. & Granville, D. J., Jan 1 2012, In : Cardiovascular Pathology. 21, 1, p. 28-38 11 p.

Research output: Contribution to journalArticle

12 Scopus citations
22 Scopus citations

Second harmonic generation microscopy differentiates collagen type I and type III in COPD

Suzuki, M., Kayra, D., Elliott, W. M., Hogg, J. C. & Abraham, T., Apr 16 2012, Multiphoton Microscopy in the Biomedical Sciences XII. 82263F. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 8226).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Scopus citations
2011

Erratum: Serpina3n attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm (Cell Death and Disease (2011) 2 (e209) DOI: 10.1038/cddis.2011.88)

Ang, L. S., Boivin, W. A., Williams, S. J., Zhao, H., Abraham, T., Carmine-Simmen, K., Mcmanus, B. M., Bleackley, R. C. & Granville, D. J., Oct 1 2011, In : Cell Death and Disease. 2, 10, e215.

Research output: Contribution to journalComment/debate

Granzyme B contributes to extracellular matrix remodeling and skin aging in apolipoprotein E knockout mice

Hiebert, P. R., Boivin, W. A., Abraham, T., Pazooki, S., Zhao, H. & Granville, D. J., Jun 1 2011, In : Experimental Gerontology. 46, 6, p. 489-499 11 p.

Research output: Contribution to journalArticle

35 Scopus citations

Mechanical force modulates scleraxis expression in bioartificial tendons

Scott, A., Danielson, P., Abraham, T., Fong, G., Sampaio, A. V. & Underhill, T. M., Jun 1 2011, In : Journal of Musculoskeletal Neuronal Interactions. 11, 2, p. 124-132 9 p.

Research output: Contribution to journalArticle

70 Scopus citations

Minimally invasive imaging method based on second harmonic generation and multiphoton excitation fluorescence in translational respiratory research

Abraham, T., Wadsworth, S., Carthy, J. M., Pechkovsky, D. V. & McManus, B., Jan 1 2011, In : Respirology. 16, 1, p. 22-33 12 p.

Research output: Contribution to journalReview article

14 Scopus citations

Minimally invasive multiphoton and harmonic generation imaging of extracellular matrix structures in lung airway and related diseases

Abraham, T., Hirota, J. A., Wadsworth, S. & Knight, D. A., Oct 1 2011, In : Pulmonary Pharmacology and Therapeutics. 24, 5, p. 487-496 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

Proteomic identification of dysferlin-interacting protein complexes in human vascular endothelium

Leung, C., Utokaparch, S., Sharma, A., Yu, C., Abraham, T., Borchers, C. & Bernatchez, P., Nov 18 2011, In : Biochemical and Biophysical Research Communications. 415, 2, p. 263-269 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Scleraxis expression is coordinately regulated in a murine model of patellar tendon injury

Scott, A., Sampaio, A., Abraham, T., Duronio, C. & Underhill, T. M., Feb 1 2011, In : Journal of Orthopaedic Research. 29, 2, p. 289-296 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Second harmonic generation analysis of early Achilles tendinosis in response to in vivo mechanical loading

Abraham, T., Fong, G. & Scott, A., Feb 2 2011, In : BMC Musculoskeletal Disorders. 12, 26.

Research output: Contribution to journalArticle

25 Scopus citations

Second harmonic generation imaging of collagen matrix remodeling in a stimulated 3D cellular environment: Forward versus backward detection

Abraham, T., Scott, A., Carthy, J. & McManus, B., May 5 2011, Multiphoton Microscopy in the Biomedical Sciences XI. 79030E. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 7903).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Serpina3n attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm

Ang, L. S., Boivin, W. A., Williams, S. J., Zhao, H., Abraham, T., Carmine-Simmen, K., McManus, B. M., Bleackley, R. C. & Granville, D. J., Sep 2011, In : Cell Death and Disease. 2, 9, p. e209

Research output: Contribution to journalArticle

37 Scopus citations

Sodium cromolyn reduces expression of CTGF, ADAMTS1, and TIMP3 and modulates post-injury patellar tendon morphology

Sharma, A., Abraham, T., Sampaio, A., Cowan, M., Underhill, M. & Scott, A., May 1 2011, In : Journal of Orthopaedic Research. 29, 5, p. 678-683 6 p.

Research output: Contribution to journalArticle

9 Scopus citations
2010
34 Scopus citations