• 1893 Citations
  • 26 h-Index
20002020

Research output per year

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Research Output

A Cholecystokinin B Receptor-Specific DNA Aptamer for Targeting Pancreatic Ductal Adenocarcinoma

Clawson, G. A., Abraham, T., Pan, W., Tang, X., Linton, S. S., McGovern, C. O., Loc, W. S., Smith, J. P., Butler, P. J., Kester, M., Adair, J. H. & Matters, G. L., Feb 2017, In : Nucleic Acid Therapeutics. 27, 1, p. 23-35 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

Adhesion forces between functionalized probes and hydrophilic silica surfaces

Christendat, D., Abraham, T., Xu, Z. & Masliyah, J., Aug 1 2005, In : Journal of Adhesion Science and Technology. 19, 3-5, p. 149-163 15 p.

Research output: Contribution to journalArticle

18 Scopus citations

Adsorption kinetics of a hydrophobic-hydrophilic diblock polyelectrolyte at the solid-aqueous solution interface: a slow birth and fast growth process

Abraham, T., Giasson, S., Gohy, J. F., Jérôme, R., Müller, B. & Stamm, M., Aug 8 2000, In : Macromolecules. 33, 16, p. 6051-6059 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure

Takahashi, Y., He, H., Tang, Z., Hattori, T., Liu, Y., Young, M. M., Serfass, J. M., Chen, L., Gebru, M., Chen, C., Wills, C. A., Xavier, J., Chen, H., Abraham, T. & Wang, H. G., Dec 1 2018, In : Nature communications. 9, 1, 2855.

Research output: Contribution to journalArticle

47 Scopus citations

A novel dual inhibitor of microtubule and Bruton's tyrosine kinase inhibits survival of multiple myeloma and osteoclastogenesis

Pandey, M. K., Gowda, K., Sung, S. S., Abraham, T., Budak-Alpdogan, T., Talamo, G., Dovat, S. & Amin, S., Sep 2017, In : Experimental Hematology. 53, p. 31-42 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

A peptide derived from melanotransferrin delivers a protein-based interleukin 1 receptor antagonist across the BBB and ameliorates neuropathic pain in a preclinical model

Thom, G., Tian, M. M., Hatcher, J. P., Rodrigo, N., Burrell, M., Gurrell, I., Vitalis, T. Z., Abraham, T., Jefferies, W. A., Webster, C. I. & Gabathuler, R., Oct 1 2019, In : Journal of Cerebral Blood Flow and Metabolism. 39, 10, p. 2074-2088 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

Asphaltene - Silica interactions in aqueous solutions: Direct force measurements combined with electrokinetic studies

Abraham, T., Christendat, D., Karan, K., Xu, Z. & Masliyah, J., May 1 2002, In : Industrial and Engineering Chemistry Research. 41, 9, p. 2170-2177 8 p.

Research output: Contribution to journalArticle

47 Scopus citations

A splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2α

Chen, S. J., Hoffman, N. E., Shanmughapriy, S., Bao, L., Keefer, K., Conrad, K., Merali, S., Takahashi, Y., Abraham, T., Hirschler-Laszkiewicz, I., Wang, J. F., Zhang, X. Q., Song, J., Barrero, C., Shi, Y., Kawasawa, Y. I., Bayerl, M., Sun, T., Barbour, M., Wang, H. G. & 3 others, Madesh, M., Cheung, J. Y. & Miller, B. A., Jan 1 2014, In : Journal of Biological Chemistry. 289, 52, p. 36284-36302 19 p.

Research output: Contribution to journalArticle

47 Scopus citations

B cell-intrinsic CD84 and Ly108 maintain germinal center B cell tolerance

Wong, E. B., Soni, C., Chan, A. Y., Domeier, P. P., Shwetank, Abraham, T., Limaye, N., Khan, T. N., Elias, M. J., Chodisetti, S. B., Wakeland, E. K. & Rahman, Z. S. M., May 1 2015, In : Journal of Immunology. 194, 9, p. 4130-4143 14 p.

Research output: Contribution to journalArticle

23 Scopus citations
34 Scopus citations

Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells

Kim, Y. S., Gupta Vallur, P., Jones, V. M., Worley, B. L., Shimko, S., Shin, D. H., Crawford, L. T. C., Chen, C. W., Aird, K. M., Abraham, T., Shepherd, T. G., Warrick, J. I., Lee, N. Y., Phaeton, R., Mythreye, K. & Hempel, N., Feb 20 2020, In : Oncogene. 39, 8, p. 1619-1633 15 p.

Research output: Contribution to journalArticle

Contribution of intimal smooth muscle cells to cholesterol accumulation and macrophage-like cells in human atherosclerosis

Allahverdian, S., Chehroudi, A. C., McManus, B. M., Abraham, T. & Francis, G. A., Jan 1 2014, In : Circulation. 129, 15, p. 1551-1559 9 p.

Research output: Contribution to journalArticle

219 Scopus citations

Cryo-imaging of inflated frozen human lung sections at -60°c using multiphoton and harmonic generation microscopy

Abraham, T. & Hogg, J. C., Aug 1 2014, In : Microscopy and Microanalysis. 20, 3, p. 1348-1349 2 p.

Research output: Contribution to journalConference article

Deconvolution and chromatic aberration corrections in quantifying colocalization of a transcription factor in three-dimensional cellular space

Abraham, T., Allan, S. E. & Levings, M. K., Aug 1 2010, In : Micron. 41, 6, p. 633-640 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Depletion of the human ion channel TRPM2 in neuroblastoma demonstrates its key role in cell survival through modulation of mitochondrial reactive oxygen species and bioenergetics

Bao, L., Chen, S. J., Conrad, K., Keefer, K., Abraham, T., Lee, J. P., Wang, J. F., Zhang, X. Q., Hirschler-Laszkiewicz, I., Wang, H. G., Dovat, S., Gans, B., Madesh, M., Cheung, J. Y. & Miller, B. A., Nov 18 2016, In : Journal of Biological Chemistry. 291, 47, p. 24449-24464 16 p.

Research output: Contribution to journalArticle

26 Scopus citations

Direct measurements of interactions between hydrophobically anchored strongly charged polyelectrolyte brushes

Abraham, T., Giasson, S., Gohy, J. F. & Jérôme, R., May 2 2000, In : Langmuir. 16, 9, p. 4286-4292 7 p.

Research output: Contribution to journalArticle

75 Scopus citations

Domain interaction studies of herpes simplex virus 1 tegument protein UL16 reveal its interaction with mitochondria

Chadha, P., Sarfo, A., Zhang, D., Abraham, T., Carmichael, J., Han, J. & Wills, J. W., Jan 1 2017, In : Journal of virology. 91, 2, e01995-16.

Research output: Contribution to journalArticle

5 Scopus citations

Early activation of matrix metalloproteinases underlies the exacerbated systolic and diastolic dysfunction in mice lacking TIMP3 following myocardial infarction

Kandalam, V., Basu, R., Abraham, T., Wang, X., Awad, A., Wang, W., Lopaschuk, G. D., Maeda, N., Oudit, G. Y. & Kassiri, Z., Oct 1 2010, In : American Journal of Physiology - Heart and Circulatory Physiology. 299, 4, p. H1012-H1023

Research output: Contribution to journalArticle

54 Scopus citations

Educating and training biomedical researchers in biophotonics and advanced light microscopy methods

Abraham, T., Jan 1 2019, Fifteenth Conference on Education and Training in Optics and Photonics, ETOP 2019. Poulin-Girard, A-S. & Shaw, J. A. (eds.). SPIE, 1114326. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 11143).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access

Effective encapsulation and biological activity of phosphorylated chemotherapeutics in calcium phosphosilicate nanoparticles for the treatment of pancreatic cancer

Loc, W. S., Linton, S. S., Wilczynski, Z. R., Matters, G., McGovern, C. O., Abraham, T., Fox, T., Gigliotti, C. M., Tang, X., Tabakovic, A., Martin, J. A., Clawson, G., Smith, J. P., Butler, P. J., Kester, M. & Adair, J. H., Oct 2017, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 13, 7, p. 2313-2324 12 p.

Research output: Contribution to journalArticle

3 Scopus citations
19 Scopus citations

ERK MAP kinase-activated Arf6 trafficking directs coxsackievirus type B3 into an unproductive compartment during virus host-cell entry

Marchant, D., Sall, A., Si, X., Abraham, T., Wu, W., Luo, Z., Petersen, T., Hegele, R. G. & McManus, B. M., Jun 29 2009, In : Journal of General Virology. 90, 4, p. 854-862 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Erratum: Serpina3n attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm (Cell Death and Disease (2011) 2 (e209) DOI: 10.1038/cddis.2011.88)

Ang, L. S., Boivin, W. A., Williams, S. J., Zhao, H., Abraham, T., Carmine-Simmen, K., Mcmanus, B. M., Bleackley, R. C. & Granville, D. J., Oct 1 2011, In : Cell Death and Disease. 2, 10, e215.

Research output: Contribution to journalComment/debate

53 Scopus citations

Extracellular vesicle-dependent effect of RNA-binding protein IGF2BP1 on melanoma metastasis

Ghoshal, A., Rodrigues, L. C., Gowda, C. P., Elcheva, I. A., Liu, Z., Abraham, T. & Spiegelman, V. S., May 23 2019, In : Oncogene. 38, 21, p. 4182-4196 15 p.

Research output: Contribution to journalArticle

3 Scopus citations

Functional effects of protein kinases and peroxynitrite on cardiac carnitine palmitoyltransferase-1 in isolated mitochondria

Sharma, V., Abraham, T., So, A., Allard, M. F. & McNeill, J. H., Apr 1 2010, In : Molecular and Cellular Biochemistry. 337, 1-2, p. 223-237 15 p.

Research output: Contribution to journalArticle

17 Scopus citations

Glycolipid based cubic nanoparticles: Preparation and structural aspects

Abraham, T., Hato, M. & Hirai, M., May 15 2004, In : Colloids and Surfaces B: Biointerfaces. 35, 2, p. 107-118 12 p.

Research output: Contribution to journalArticle

40 Scopus citations

Granzyme B contributes to extracellular matrix remodeling and skin aging in apolipoprotein E knockout mice

Hiebert, P. R., Boivin, W. A., Abraham, T., Pazooki, S., Zhao, H. & Granville, D. J., Jun 1 2011, In : Experimental Gerontology. 46, 6, p. 489-499 11 p.

Research output: Contribution to journalArticle

35 Scopus citations
1 Scopus citations

Increased mast cell numbers in a calcaneal tendon overuse model

Pingel, J., Wienecke, J., Kongsgaard, M., Behzad, H., Abraham, T., Langberg, H. & Scott, A., Dec 2013, In : Scandinavian Journal of Medicine and Science in Sports. 23, 6, p. e353-e360

Research output: Contribution to journalArticle

24 Scopus citations

Inducible reprogramming of human T cells into Treg cells by a conditionally active form of FOXP3

Allan, S. E., Song-Zhao, G. X., Abraham, T., McMurchy, A. N. & Levings, M. K., Dec 1 2008, In : European Journal of Immunology. 38, 12, p. 3282-3289 8 p.

Research output: Contribution to journalArticle

88 Scopus citations
6 Scopus citations

Isothermal titration calorimetry studies of the binding of a rationally designed analogue of the antimicrobial peptide gramicidin S to phospholipid bilayer membranes

Abraham, T., Lewis, R. N. A. H., Hodges, R. S. & McElhaney, R. N., Feb 15 2005, In : Biochemistry. 44, 6, p. 2103-2112 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

Isothermal titration calorimetry studies of the binding of the antimicrobial peptide gramicidin S to phospholipid bilayer membranes

Abraham, T., Lewis, R. N. A. H., Hodges, R. S. & McElhaney, R. N., Aug 23 2005, In : Biochemistry. 44, 33, p. 11279-11285 7 p.

Research output: Contribution to journalArticle

37 Scopus citations
Open Access

Localization of DNA and RNA in eosinophil secretory granules

Behzad, A. R., Walker, D. C., Abraham, T., McDonough, J., Mahmudi-Azer, S., Chu, F., Shaheen, F., Hogg, J. C. & Paré, P. D., Apr 2010, In : International Archives of Allergy and Immunology. 152, 1, p. 12-27 16 p.

Research output: Contribution to journalArticle

8 Scopus citations

Lung alveolar wall disruption in three-dimensional space identified using second-harmonic generation and multiphoton excitation fluorescence

Abraham, T. & Hogg, J., May 7 2010, Advanced Biomedical and Clinical Diagnostic Systems VIII. 75550X. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 7555).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

28 Scopus citations

Mechanical force modulates scleraxis expression in bioartificial tendons

Scott, A., Danielson, P., Abraham, T., Fong, G., Sampaio, A. V. & Underhill, T. M., Jun 1 2011, In : Journal of Musculoskeletal Neuronal Interactions. 11, 2, p. 124-132 9 p.

Research output: Contribution to journalArticle

70 Scopus citations

Minimally invasive imaging method based on second harmonic generation and multiphoton excitation fluorescence in translational respiratory research

Abraham, T., Wadsworth, S., Carthy, J. M., Pechkovsky, D. V. & McManus, B., Jan 1 2011, In : Respirology. 16, 1, p. 22-33 12 p.

Research output: Contribution to journalReview article

14 Scopus citations

Minimally invasive multiphoton and harmonic generation imaging of extracellular matrix structures in lung airway and related diseases

Abraham, T., Hirota, J. A., Wadsworth, S. & Knight, D. A., Oct 1 2011, In : Pulmonary Pharmacology and Therapeutics. 24, 5, p. 487-496 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

miR-33a modulates ABCA1 expression, cholesterol accumulation, and insulin secretion in pancreatic islets

Wijesekara, N., Zhang, L. H., Kang, M. H., Abraham, T., Bhattacharjee, A., Warnock, G. L., Verchere, C. B. & Hayden, M. R., Mar 1 2012, In : Diabetes. 61, 3, p. 653-658 6 p.

Research output: Contribution to journalArticle

89 Scopus citations

Monolayer film behavior of lipopolysaccharide from Pseudomonas aeruginosa at the air-water interface

Abraham, T., Schooling, S. R., Beveridge, T. J. & Katsaras, J., Oct 1 2008, In : Biomacromolecules. 9, 10, p. 2799-2804 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Multiphoton and harmonic generation imaging methods enable direct visualization of drug nanoparticle carriers in conjunction with vasculature in fibrotic prostate tumor mouse model

Abraham, T., Clawson, G. A., McGovern, C. O., Edris, W., Tang, X., Adair, J. H. & Matters, G. L., Jan 1 2019, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVII. Tarnok, A., Leary, J. F. & Farkas, D. L. (eds.). SPIE, 108811T. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10881).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Multiphoton microscopy based cryo-imaging of inflated frozen human lung sections at -60OC in healthy and COPD lungs

Abraham, T., Kayra, D., Zhang, A., Suzuki, M., McDonagh, J., Elliott, W. M., Cooper, J. D. & Hogg, J. C., 2013, Multiphoton Microscopy in the Biomedical Sciences XIII. 85881Q. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 8588).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Neutron diffraction study of pseudomonas aeruginosa lipopolysaccharide bilayers

Abraham, T., Schooling, S. R., Nieh, M. P., Kučerka, N., Beveridge, T. J. & Katsaras, J., Mar 15 2007, In : Journal of Physical Chemistry B. 111, 10, p. 2477-2483 7 p.

Research output: Contribution to journalArticle

37 Scopus citations

PIGN gene expression aberration is associated with genomic instability and leukemic progression in acute myeloid leukemia with myelodysplastic features

Teye, E. K., Sido, A., Xin, P., Finnberg, N. K., Gokare, P., Kawasawa, Y. I., Salzberg, A. C., Shimko, S., Bayerl, M., Ehmann, W. C., Claxton, D. F., Rybka, W. B., Drabick, J. J., Wang, H. G., Abraham, T., El-Deiry, W. S., Brodsky, R. A., J.Hohl, R. & Pu, J. J., 2017, In : Oncotarget. 8, 18, p. 29887-29905 19 p.

Research output: Contribution to journalArticle

3 Scopus citations

Podocalyxin regulates murine lung vascular permeability by altering endothelial cell adhesion

Debruin, E. J., Hughes, M. R., Sina, C., Liu, A., Cait, J., Jian, Z., Lopez, M., Lo, B., Abraham, T. & McNagny, K. M., Oct 10 2014, In : PloS one. 9, 10, e108881.

Research output: Contribution to journalArticle

20 Scopus citations

Polyelectrolyte-mediated interaction between similarly charged surfaces: Role of divalent counter ions in tuning surface forces

Abraham, T., Kumpulainen, A., Xu, Z., Rutland, M., Claesson, P. M. & Masliyah, J., Dec 25 2001, In : Langmuir. 17, 26, p. 8321-8327 7 p.

Research output: Contribution to journalArticle

37 Scopus citations