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Thomas Ma, MD, PhD

    • 5226 Citations
    • 39 h-Index
    1989 …2023
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    • 5 Similar Profiles
    Tight Junctions Medicine & Life Sciences
    Permeability Medicine & Life Sciences
    Myosin-Light-Chain Kinase Medicine & Life Sciences
    Occludin Medicine & Life Sciences
    Epithelial Cells Medicine & Life Sciences
    Monolayers Chemical Compounds
    Interleukin-1 Medicine & Life Sciences
    Caco-2 Cells Medicine & Life Sciences

    Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Projects 1989 2023

    Intestinal Barrier, Probiotic Bacteria, and the Gut-Liver Axis

    Ma, T.

    National Institutes of Health

    3/18/19 → 12/31/23

    Project: Research project

    Tight Junctions
    Probiotics
    Bacteria
    Permeability
    Liver

    Bifidobacterium bifidum modulation of intestinal barrier and intestinal inflammation.

    Ma, T.

    National Institutes of Health

    7/1/16 → 6/30/20

    Project: Research project

    Tight Junctions
    Inflammation
    Inflammatory Bowel Diseases
    Myosin-Light-Chain Kinase
    Animal Models

    INTESTINAL PERMEABILITY OF MOLECULAR PROBES

    Ma, T.

    National Institutes of Health

    3/15/89 → …

    Project: Research project

    Regulation of Intestinal Epithelial Tight Junction Barrier

    Ma, T.

    National Institutes of Health

    4/1/11 → 9/30/16

    Project: Research project

    Tight Junctions
    Lipopolysaccharides
    Permeability
    Myosin-Light-Chain Kinase
    Toll-Like Receptor 4

    Autophagy and Crohn's Disease

    Ma, T. & Deretic, V.

    National Institutes of Health

    9/26/09 → 8/31/12

    Project: Research project

    Autophagy
    Crohn Disease
    Mucosal Immunity
    Inflammatory Bowel Diseases
    Genes

    Research Output 1989 2019

    • 5226 Citations
    • 39 h-Index
    • 85 Article
    • 3 Chapter
    • 3 Letter
    • 3 Review article

    Intestinal epithelial tight junction barrier regulation by autophagy-related protein ATG6/beclin 1

    Wong, M., Ganapathy, A. S., Suchanec, E., Laidler, L., Ma, T. & Nighot, P., May 1 2019, In : American Journal of Physiology - Cell Physiology. 316, 5, p. C753-C765

    Research output: Contribution to journal › Article

    Tight Junctions
    Occludin
    Autophagy
    Caco-2 Cells
    Endocytosis

    Investigating intestinal permeability and gut microbiota roles in acute coronary syndrome patients

    Alhmoud, T., Kumar, A., Lo, C. C., Al-Sadi, R., Clegg, S., Alomari, I., Zmeili, T., Gleasne, C. D., Mcmurry, K., Dichosa, A. E. K., Vuyisich, M., Chain, P. S. G., Mishra, S. & Ma, T., Aug 1 2019, In : Human Microbiome Journal. 13, 100059.

    Research output: Contribution to journal › Article

    Open Access
    Acute Coronary Syndrome
    Permeability
    Proteobacteria
    Lipopolysaccharides
    Dysbiosis
    2 Citations (Scopus)

    Lipopolysaccharide-Induced Increase in Intestinal Permeability Is Mediated by TAK-1 Activation of IKK and MLCK/MYLK Gene

    Nighot, M., Rawat, M., Al-Sadi, R., Castillo, E. F., Nighot, P. & Ma, T., Apr 1 2019, In : American Journal of Pathology. 189, 4, p. 797-812 16 p.

    Research output: Contribution to journal › Article

    Myosin-Light-Chain Kinase
    Tight Junctions
    Lipopolysaccharides
    Permeability
    Genes

    MMP-9-induced increase in intestinal epithelial tight permeability is mediated by p38 kinase signaling pathway activation of MLCK gene

    Al-Sadi, R., Youssef, M., Rawat, M., Guo, S., Dokladny, K., Haque, M., Watterson, M. D. & Ma, T., Feb 1 2019, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 316, 2, p. G278-G290

    Research output: Contribution to journal › Article

    Myosin-Light-Chain Kinase
    MAP Kinase Signaling System
    Matrix Metalloproteinase 9
    Permeability
    Tight Junctions
    8 Citations (Scopus)

    Expression of programmed death-ligand 1 by human colonic CD90+ stromal cells differs between ulcerative colitis and Crohn's disease and determines their capacity to suppress Th1 cells

    Beswick, E. J., Grim, C., Singh, A., Aguirre, J. E., Tafoya, M., Qiu, S., Rogler, G., McKee, R., Samedi, V., Ma, T., Reyes, V. E., Powell, D. W. & Pinchuk, I., May 30 2018, In : Frontiers in immunology. 9, MAY, 1125.

    Research output: Contribution to journal › Article

    Th1 Cells
    Stromal Cells
    Ulcerative Colitis
    Crohn Disease
    Fibroblasts