If you made any changes in Pure these will be visible here soon.

Research Output

  • 1264 Citations
  • 15 h-Index
  • 26 Article
  • 11 Chapter
  • 5 Review article
  • 1 Book
2020

Incidence, Risk Factors, and Outcomes of Patients Who Develop Mucosal Barrier Injury-Laboratory Confirmed Bloodstream Infections in the First 100 Days After Allogeneic Hematopoietic Stem Cell Transplant

Dandoy, C. E., Kim, S., Chen, M., Ahn, K. W., Ardura, M. I., Brown, V., Chhabra, S., Diaz, M. A., Dvorak, C., Farhadfar, N., Flagg, A., Ganguly, S., Hale, G. A., Hashmi, S. K., Hematti, P., Martino, R., Nishihori, T., Nusrat, R., Olsson, R. F., Rotz, S. J. & 5 others, Sung, A. D., Perales, M. A., Lindemans, C. A., Komanduri, K. V. & Riches, M. L., Jan 3 2020, In : JAMA network open. 3, 1, p. e1918668

Research output: Contribution to journalArticle

Open Access
2019

Bacterial blood stream infections (BSIs), particularly post-engraftment BSIs, are associated with increased mortality after allogeneic hematopoietic cell transplantation

Ustun, C., Young, J. A. H., Papanicolaou, G. A., Kim, S., Ahn, K. W., Chen, M., Abdel-Azim, H., Aljurf, M., Beitinjaneh, A., Brown, V., Cerny, J., Chhabra, S., Kharfan-Dabaja, M. A., Dahi, P. B., Daly, A., Dandoy, C. E., Dvorak, C. C., Freytes, C. O., Hashmi, S., Lazarus, H. & 13 others, Ljungman, P., Nishihori, T., Page, K., Pingali, S. R. K., Saad, A., Savani, B. N., Weisdorf, D., Williams, K., Wirk, B., Auletta, J. J., Lindemans, C. A., Komanduri, K. & Riches, M., Aug 1 2019, In : Bone Marrow Transplantation. 54, 8, p. 1254-1265 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Increased overall and bacterial infections following myeloablative allogeneic HCT for patients with AML in CR1

Ustun, C., Kim, S., Chen, M., Beitinjaneh, A. M., Brown, V. I., Dahi, P. B., Daly, A., Diaz, M. A., Freytes, C. O., Ganguly, S., Hashmi, S., Hildebrandt, G. C., Lazarus, H. M., Nishihori, T., Olsson, R. F., Page, K. M., Papanicolaou, G., Saad, A., Seo, S., William, B. M. & 8 others, Wingard, J. R., Wirk, B., Yared, J. A., Perales, M. A., Auletta, J. J., Komanduri, K. V., Lindemans, C. A. & Riches, M. L., Sep 10 2019, In : Blood Advances. 3, 17, p. 2525-2536 12 p.

Research output: Contribution to journalArticle

Open Access

Outcomes after Second Hematopoietic Cell Transplantation in Children and Young Adults with Relapsed Acute Leukemia

Lund, T. C., Ahn, K. W., Tecca, H. R., Hilgers, M. V., Abdel-Azim, H., Abraham, A., Diaz, M. A., Badawy, S. M., Broglie, L., Brown, V., Dvorak, C. C., Gonzalez-Vicent, M., Hashem, H., Hayashi, R. J., Jacobsohn, D. A., Kent, M. W., Li, C. K., Margossian, S. P., Martin, P. L., Mehta, P. & 9 others, Myers, K., Olsson, R., Page, K., Pulsipher, M. A., Shaw, P. J., Smith, A. R., Triplett, B. M., Verneris, M. R. & Eapen, M., Feb 2019, In : Biology of Blood and Marrow Transplantation. 25, 2, p. 301-306 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Survival outcomes of allogeneic hematopoietic cell transplants with EBV-positive or EBV-negative post-transplant lymphoproliferative disorder, A CIBMTR study

Naik, S., Riches, M., Hari, P., Kim, S., Chen, M., Bachier, C., Shaughnessy, P., Hill, J., Ljungman, P., Battiwalla, M., Chhabra, S., Daly, A., Storek, J., Ustun, C., Diaz, M. A., Cerny, J., Beitinjaneh, A., Yared, J., Brown, V., Page, K. & 13 others, Dahi, P. B., Ganguly, S., Seo, S., Chao, N., Freytes, C. O., Saad, A., Savani, B. N., Woo Ahn, K., Boeckh, M., Heslop, H. E., Lazarus, H. M., Auletta, J. J. & Kamble, R. T., Oct 1 2019, In : Transplant Infectious Disease. 21, 5, e13145.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Dasatinib plus intensive chemotherapy in children, adolescents, and young adults with philadelphia chromosome–positive acute lymphoblastic leukemia: Results of children’s oncology group trial AALL0622

Slayton, W. B., Schultz, K. R., Kairalla, J. A., Devidas, M., Mi, X., Pulsipher, M. A., Chang, B. H., Mullighan, C., Iacobucci, I., Silverman, L. B., Borowitz, M. J., Carroll, A. J., Heerema, N. A., Gastier-Foster, J. M., Wood, B. L., Mizrahy, S. L., Merchant, T., Brown, V. I., Sieger, L., Siegel, M. J. & 5 others, Raetz, E. A., Winick, N. J., Loh, M. L., Carroll, W. L. & Hunger, S. P., Aug 1 2018, In : Journal of Clinical Oncology. 36, 22, p. 2306-2313 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Graft-versus-host disease

Brown, V., Jan 1 2018, The 5-Minute Pediatric Consult, 8th Edition. Wolters Kluwer Health, p. 402-403 2 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Maintenance DFMO Increases Survival in High Risk Neuroblastoma

Sholler, G. L. S., Ferguson, W., Bergendahl, G., Bond, J. P., Neville, K., Eslin, D., Brown, V., Roberts, W., Wada, R. K., Oesterheld, J., Mitchell, D., Foley, J., Parikh, N. S., Eshun, F., Zage, P., Rawwas, J., Sencer, S., Pankiewicz, D., Quinn, M., Rich, M. & 2 others, Junewick, J. & Kraveka, J. M., Dec 1 2018, In : Scientific reports. 8, 1, 14445.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations
2017

Brief introduction to the basic scientific principles of hematopoietic stem cell transplantation (HSCT)

Brown, V. I., Jan 1 2017, Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist. Springer International Publishing, p. 19-53 35 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cardiac complications associated with HSCT

Brown, V., Jan 1 2017, Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist. Springer International Publishing, p. 333-341 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Engraftment and chimerism

Brown, V. I., Jan 1 2017, Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist. Springer International Publishing, p. 177-186 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Graft failure

Brown, V., Jan 1 2017, Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist. Springer International Publishing, p. 187-194 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hematopoietic Stem Cell Transplantation Activity in Pediatric Cancer between 2008 and 2014 in the United States: A Center for International Blood and Marrow Transplant Research Report

Khandelwal, P., Millard, H. R., Thiel, E., Abdel-Azim, H., Abraham, A. A., Auletta, J. J., Boulad, F., Brown, V., Camitta, B. M., Chan, K. W., Chaudhury, S., Cowan, M. J., Angel-Diaz, M., Gadalla, S. M., Gale, R. P., Hale, G., Kasow, K. A., Keating, A. K., Kitko, C. L., MacMillan, M. L. & 7 others, Olsson, R. F., Page, K. M., Seber, A., Smith, A. R., Warwick, A. B., Wirk, B. & Mehta, P. A., Aug 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 8, p. 1342-1349 8 p.

Research output: Contribution to journalArticle

13 Scopus citations
1 Scopus citations

Hepatotoxicity in the peri-HSCT period

Brown, V. I., Jan 1 2017, Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist. Springer International Publishing, p. 215-233 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Historical overview of pediatric HSCT

Brown, V., Jan 1 2017, Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist. Springer International Publishing, p. 7-18 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

HSCT-associated complications of the skin, hair, and nails

Brown, V. I., Jan 1 2017, Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist. Springer International Publishing, p. 363-368 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

HSCT recipient pretransplantation evaluation

Eichelberger, C. & Brown, V., Jan 1 2017, Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist. Springer International Publishing, p. 91-96 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Introduction

Brown, V. I., Jan 1 2017, Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist. Springer International Publishing, p. 3-5 3 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neurologic and sensory complications associated with HSCT

Brown, V., Jan 1 2017, Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist. Springer International Publishing, p. 343-361 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Personalized Prognostic Risk Score for Long-Term Survival for Children with Acute Leukemia after Allogeneic Transplantation

Bitan, M., Ahn, K. W., Millard, H. R., Pulsipher, M. A., Abdel-Azim, H., Auletta, J. J., Brown, V., Chan, K. W., Diaz, M. A., Dietz, A., Vincent, M. G., Guilcher, G., Hale, G. A., Hayashi, R. J., Keating, A., Mehta, P., Myers, K., Page, K., Prestidge, T., Shah, N. N. & 5 others, Smith, A. R., Woolfrey, A., Thiel, E., Davies, S. M. & Eapen, M., Sep 2017, In : Biology of Blood and Marrow Transplantation. 23, 9, p. 1523-1530 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
2015

Transplant Outcomes for Children with T Cell Acute Lymphoblastic Leukemia in Second Remission: A Report from the Center for International Blood and Marrow Transplant Research

Burke, M. J., Verneris, M. R., Le Rademacher, J., He, W., Abdel-Azim, H., Abraham, A. A., Auletta, J. J., Ayas, M., Brown, V., Cairo, M. S., Chan, K. W., Diaz Perez, M. A., Dvorak, C. C., Egeler, R. M., Eldjerou, L., Frangoul, H., Guilcher, G. M. T., Hayashi, R. J., Ibrahim, A., Kasow, K. A. & 8 others, Leung, W. H., Olsson, R. F., Pulsipher, M. A., Shah, N., Shah, N. N., Thiel, E., Talano, J. A. & Kitko, C. L., Dec 1 2015, In : Biology of Blood and Marrow Transplantation. 21, 12, p. 2154-2159 6 p.

Research output: Contribution to journalArticle

12 Scopus citations
2014

Targeted Busulfan therapy with a steady-state concentration of 600-700 ng/mL in patients with sickle cell disease receiving HLA-identical sibling bone marrow transplant

Maheshwari, S., Kassim, A., Yeh, R. F., Domm, J., Calder, C., Evans, M., Manes, B., Bruce, K., Brown, V., Ho, R., Frangoul, H. & Yang, E., Mar 1 2014, In : Bone Marrow Transplantation. 49, 3, p. 366-369 4 p.

Research output: Contribution to journalArticle

19 Scopus citations
2013

Incidence and risk factors for hypogammaglobulinemia in pediatric patients following allo-SCT

Frangoul, H., Min, E., Wang, W., Chandrasekhar, R., Calder, C., Evans, M., Manes, B., Bruce, K., Brown, V., Ho, R. & Domm, J., Nov 1 2013, In : Bone Marrow Transplantation. 48, 11, p. 1456-1459 4 p.

Research output: Contribution to journalArticle

8 Scopus citations
2012

A single-center study of hematopoietic stem cell transplantation for primary immune deficiencies (PIDD)

Dinardo, L., Brown, V., Perez, E., Bunin, N. & Sullivan, K. E., Feb 1 2012, In : Pediatric Transplantation. 16, 1, p. 63-72 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Targeting the PI3KAKTmTOR signaling axis in children with hematologic malignancies

Barrett, D., Brown, V. I., Grupp, S. A. & Teachey, D. T., Aug 30 2012, In : Pediatric Drugs. 14, 5, p. 299-316 18 p.

Research output: Contribution to journalReview article

78 Scopus citations
2009

Long-term protection from syngeneic acute lymphoblastic leukemia by CpG ODN-mediated stimulation of innate and adaptive immune responses

Seif, A. E., Barrett, D. M., Milone, M., Brown, V. I., Grupp, S. A. & Reid, G. S. D., Nov 19 2009, In : Blood. 114, 12, p. 2459-2466 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Mammalian target of rapamycin inhibitors and their potential role in therapy in leukaemia and other haematological malignancies

Teachey, D. T., Grupp, S. A. & Brown, V., Jun 1 2009, In : British Journal of Haematology. 145, 5, p. 569-580 12 p.

Research output: Contribution to journalReview article

95 Scopus citations
2008

mTOR inhibitors are synergistic with methotrexate: An effective combination to treat acute lymphoblastic leukemia

Teachey, D. T., Sheen, C., Hall, J., Ryan, T., Brown, V. I., Fish, J., Reid, G. S. D., Seif, A. E., Norris, R., Chang, Y. J., Carroll, M. & Grupp, S. A., Sep 1 2008, In : Blood. 112, 5, p. 2020-2023 4 p.

Research output: Contribution to journalArticle

89 Scopus citations

Novel molecular and cellular therapeutic targets in acute lymphoblastic leukemia and lymphoproliferative disease

Brown, V., Seif, A. E., Reid, G. S. D., Teachey, D. T. & Grupp, S. A., Aug 22 2008, In : Immunologic Research. 42, 1-3, p. 84-105 22 p.

Research output: Contribution to journalReview article

26 Scopus citations

Targeting Notch signaling in autoimmune and lymphoproliferative disease

Teachey, D. T., Seif, A. E., Brown, V. I., Bruno, M., Bunte, R. M., Chang, Y. J., Choi, J. K., Fish, J. D., Hall, J., Reid, G. S., Ryan, T., Sheen, C., Zweidler-McKay, P. & Grupp, S. A., Jan 15 2008, In : Blood. 111, 2, p. 705-714 10 p.

Research output: Contribution to journalArticle

61 Scopus citations
2007

Thymic stromal-derived lymphopoietin induces proliferation of pre-B leukemia and antagonizes mTOR inhibitors, suggesting a role for interleukin-7Rα signaling

Brown, V., Hulitt, J., Fish, J., Sheen, C., Bruno, M., Xu, Q., Carroll, M., Fang, J., Teachey, D. & Grupp, S. A., Oct 15 2007, In : Cancer Research. 67, 20, p. 9963-9970 8 p.

Research output: Contribution to journalArticle

47 Scopus citations
2006

Rapamycin improves lymphoproliferative disease in murine autoimmune lymphoproliferative syndrome (ALPS)

Teachey, D. T., Obzut, D. A., Axsom, K., Choi, J. K., Goldsmith, K. C., Hall, J., Hulitt, J., Manno, C. S., Maris, J. M., Rhodin, N., Sullivan, K. E., Brown, V. I. & Grupp, S. A., Sep 15 2006, In : Blood. 108, 6, p. 1965-1971 7 p.

Research output: Contribution to journalArticle

66 Scopus citations

The mTOR inhibitor CCI-779 induces apoptosis and inhibits growth in preclinical models of primary adult human ALL

Teachey, D. T., Obzut, D. A., Cooperman, J., Fang, J., Carroll, M., Choi, J. K., Houghton, P. J., Brown, V. I. & Grupp, S. A., Feb 1 2006, In : Blood. 107, 3, p. 1149-1155 7 p.

Research output: Contribution to journalArticle

139 Scopus citations
2003

Rapamycin is active against B-precursor leukemia in vitro and in vivo, an effect that is modulated by IL-7-mediated signaling

Brown, V. I., Fang, J., Alcorn, K., Barr, R., Kim, J. M., Wasserman, R. & Grupp, S. A., Dec 9 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 25, p. 15113-15118 6 p.

Research output: Contribution to journalArticle

133 Scopus citations

Role of the BCR complex in B cell development, activation, and leukemic transformation

Rheingold, S. R., Brown, V. I., Fang, J., Kim, J. M. & Grupp, S. A., Aug 28 2003, In : Immunologic Research. 27, 2-3, p. 309-329 21 p.

Research output: Contribution to journalReview article

1 Scopus citations
1994

Demonstration by Two-Color Flow Cytometry That Tyrosine Kinase Activity Is Required for Down-Modulation of the Oncogenic neu Receptor

Brown, V., Shah, N., Smith, R., Hellman, M., Jarett, L., Mikami, Y., Cohen, E., Qian, X. & Greene, M. I., Jan 1 1994, In : DNA and Cell Biology. 13, 2, p. 193-209 17 p.

Research output: Contribution to journalArticle

10 Scopus citations
1992

Carboxyl-terminal deletion and point mutations decrease the transforming potential of the activated rat neu oncogene product

Mikami, Y., Davis, J. G., Dobashi, K., Dougall, W. C., Myers, J. N., Brown, V. I. & Greene, M. I., Jan 1 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 16, p. 7335-7339 5 p.

Research output: Contribution to journalArticle

14 Scopus citations
1991

Molecular and Cellular Mechanisms of Receptor-Mediated Endocytosis

Brown, V. & Greene, M. I., Jan 1 1991, In : DNA and Cell Biology. 10, 6, p. 399-409 11 p.

Research output: Contribution to journalArticle

54 Scopus citations
1990

Anti-receptor antibodies reverse the phenotype of cells transformed by two interacting proto-oncogene encoded receptor proteins

Wada, T., Myers, J. N., Kokai, Y., Brown, V. I., Hamuro, J., LeVea, C. M. & Greene, M. I., May 7 1990, In : Oncogene. 5, 4, p. 489-495 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Susceptibility of human neuroblastoma cell lines to cytotoxic T lymphocyte-mediated lysis

Zier, K. S., Pierson, G. R. & Brown, V., Jul 1990, In : Journal of Neuroimmunology. 28, 2, p. 153-160 8 p.

Research output: Contribution to journalArticle

7 Scopus citations
1989

Synergistic interaction of p185c-neu and the EGF receptor leads to transformation of rodent fibroblasts

Kokai, Y., Myers, J. N., Wada, T., Brown, V. I., LeVea, C. M., Davis, J. G., Dobashi, K. & Greene, M. I., Jul 28 1989, In : Cell. 58, 2, p. 287-292 6 p.

Research output: Contribution to journalArticle

273 Scopus citations
1988

The role of the neu oncogene product in cell transformation and normal development.

Kokai, Y., Wada, T., Myers, J. N., Brown, V. I., Dobashi, K., Cohen, J., Hamuro, J., Weiner, D. B. & Greene, M. I., 1988, In : Princess Takamatsu symposia. 19, p. 45-57 13 p.

Research output: Contribution to journalReview article

1 Scopus citations