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Vladimir Spiegelman, MD, PhD

    • 2406 Citations
    • 28 h-Index
    1992 …2019
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    • 4 Similar Profiles
    Catenins Medicine & Life Sciences
    Melanoma Medicine & Life Sciences
    Ubiquitin-Protein Ligases Medicine & Life Sciences
    Messenger RNA Medicine & Life Sciences
    Carrier Proteins Medicine & Life Sciences
    Wnt Signaling Pathway Medicine & Life Sciences
    Neoplasms Medicine & Life Sciences
    RNA-Binding Proteins Medicine & Life Sciences

    Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Projects 2007 2019

    CRD-BP-mediated regulation of Wnt signaling in intestinal tumorigenesis

    Spiegelman, V.

    National Institutes of Health

    12/1/14 → 11/30/17

    Project: Research project

    Catenins
    Carcinogenesis
    Colorectal Neoplasms
    Wnt Signaling Pathway
    myc Genes

    RNA-binding protein CRD-BP in melanocyte biology

    Spiegelman, V.

    National Institutes of Health

    2/11/13 → 1/31/19

    Project: Research project

    RNA-Binding Proteins
    Melanocytes
    Transcription Factors
    Catenins
    Messenger RNA

    The Role of CRD-BP-regulated mRNA Stability in Colorectal Cancers

    Spiegelman, V.

    National Institutes of Health

    3/1/07 → 1/31/13

    Project: Research project

    Catenins
    RNA Stability
    Colorectal Neoplasms
    Carcinogenesis
    Messenger RNA

    Research Output 1992 2019

    A novel hiPSC-derived system for hematoendothelial and myeloid blood toxicity screens identifies compounds promoting and inhibiting endothelial-to-hematopoietic transition

    Elcheva, I., Sneed, M., Frazee, S., Liu, Z., Zhu, J., Wood, T., Hendrickson, S., Oehler, C., Garcia, B. & Spiegelman, V. S., Dec 2019, In : Toxicology in Vitro. 61, 104622.

    Research output: Contribution to journal › Article

    Induced Pluripotent Stem Cells
    Cytotoxicity
    Toxicity
    GATA2 Transcription Factor
    Screening
    2 Citations (Scopus)

    Extracellular vesicle-dependent effect of RNA-binding protein IGF2BP1 on melanoma metastasis

    Ghoshal, A., Rodrigues, L. C., Gowda, C. P., Elcheva, I. A., Liu, Z., Abraham, T. & Spiegelman, V. S., May 23 2019, In : Oncogene. 38, 21, p. 4182-4196 15 p.

    Research output: Contribution to journal › Article

    Insulin-Like Growth Factor Binding Protein 2
    RNA-Binding Proteins
    Melanoma
    Neoplasm Metastasis
    Messenger RNA
    1 Citation (Scopus)

    Loss of miR-155 upregulates WEE1 in metastatic melanoma

    Disano, J. A., Huffnagle, I., Gowda, R., Spiegelman, V., Robertson, G. & Pameijer, C. R., Apr 1 2019, In : Melanoma Research. 29, 2, p. 216-219 4 p.

    Research output: Contribution to journal › Article

    Melanoma
    Up-Regulation
    Neoplasm Metastasis
    MicroRNAs
    Protein Kinases

    RNA-binding protein IGF2BP1 maintains leukemia stem cell properties by regulating HOXB4, MYB, and ALDH1A1

    Elcheva, I. A., Wood, T., Chiarolanzio, K., Chim, B., Wong, M., Singh, V., Gowda, C. P., Lu, Q., Hafner, M., Dovat, S., Liu, Z., Muljo, S. A. & Spiegelman, V. S., Jan 1 2019, (Accepted/In press) In : Leukemia.

    Research output: Contribution to journal › Article

    Insulin-Like Growth Factor Binding Protein 2
    RNA-Binding Proteins
    Leukemia
    Stem Cells
    Messenger RNA
    3 Citations (Scopus)

    Cross-talk between Wnt and Hh signaling pathways in the pathology of basal cell carcinoma

    Noubissi, F. K., Yedjou, C. G., Spiegelman, V. S. & Tchounwou, P. B., Jul 9 2018, In : International journal of environmental research and public health. 15, 7, 1442.

    Research output: Contribution to journal › Review article

    Wnt Signaling Pathway
    Hedgehogs
    Basal Cell Carcinoma
    Pathology
    Insulin-Like Growth Factor Binding Protein 2