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Personal profile

Research interests

Dr. Vonn Walter's primary research field is cancer genomics, particularly gene expression profiling, DNA copy number analysis and integrated analysis of multiple genomic data types. He is interested in all aspects of RNA sequencing data analysis, including pre-processing, normalization, differential expression analysis, unsupervised clustering, development of gene expression classifiers, pathway analysis, and network analysis. His PhD thesis led to the development of the DiNAMIC algorithm for assessing the statistical significance of recurrent genomic aberrations, such as regions of the genome where DNA copy number gains or losses are observed across multiple subjects. He also created the mVisAGe R package for computing and visualizing bivariate correlations that can be used to perform exploratory analyses for identifying regions of the genome where underling genomic aberrations affect the expression of regional genes.

Dr. Walter enjoys team science, and plays a variety of roles in ongoing collaborations with researchers at Penn State College of Medicine and elsewhere. He is a member of the Biostatistics/Bioinformatics Shared Resource of Penn State Cancer Institute.

Education/Academic qualification

Postdoctoral Fellow, Lineberger Comprehensive Cancer Center

Aug 2010Apr 2013

Biostatistics, PhD, University of North Carolina Chapel Hill

Aug 2005Jul 2010

Fingerprint Dive into the research topics where Vonn Walter is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Neoplasms Medicine & Life Sciences
Tumors Chemical Compounds
Mutation Medicine & Life Sciences
Genes Chemical Compounds
DNA Medicine & Life Sciences
Thyroid Neoplasms Medicine & Life Sciences
Squamous Cell Carcinoma Medicine & Life Sciences
RNA Sequence Analysis Medicine & Life Sciences

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Research Output 2011 2019

  • 5627 Citations
  • 19 h-Index
  • 39 Article
  • 3 Comment/debate
  • 1 Chapter

Characterization of histone deacetylase expression within in vitro and in vivo bladder cancer model systems

Buckwalter, J. M., Chan, W., Shuman, L., Wildermuth, T., Ellis-Mohl, J., Walter, V., Warrick, J., Wu, X. R., Kaag, M. G., Raman, J. & Degraff, D., May 2 2019, In : International journal of molecular sciences. 20, 10, 2599.

Research output: Contribution to journalArticle

Open Access
Histone Deacetylases
bladder
Polymerase chain reaction
Urinary Bladder Neoplasms
cancer

Circulating microRNAs in plasma among men with low-grade and high-grade prostate cancer at prostate biopsy

McDonald, A., Vira, M., Walter, V., Shen, J., Raman, J., Sanda, M. G., Patil, D. & Taioli, E., Jun 15 2019, In : Prostate. 79, 9, p. 961-968 8 p.

Research output: Contribution to journalArticle

MicroRNAs
Prostatic Neoplasms
Biopsy
Neoplasm Grading
Prostate-Specific Antigen
1 Citation (Scopus)

Gene Expression Subtype Predicts Nodal Metastasis and Survival in Human Papillomavirus–Negative Head and Neck Cancer

Zevallos, J. P., Mazul, A. L., Walter, V. & Hayes, D. N., Jan 1 2019, In : Laryngoscope. 129, 1, p. 154-161 8 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Squamous Cell Carcinoma
Neoplasm Metastasis
Gene Expression
Survival
8 Citations (Scopus)
Urinary Bladder Neoplasms
Neoplasms
Histology
Selection Bias
Carcinoma
Papillary Carcinoma
Recurrence
Neoplasms
Proportional Hazards Models
Neoplasm Grading