If you made any changes in Pure, your changes will be visible here soon.

Research Output 2011 2019

  • 6443 Citations
  • 22 h-Index
  • 45 Article
  • 3 Comment/debate
  • 1 Chapter
Filter
Article
2019
1 Citation (Scopus)

Characterization of histone deacetylase expression within in vitro and in vivo bladder cancer model systems

Buckwalter, J. M., Chan, W., Shuman, L., Wildermuth, T., Ellis-Mohl, J., Walter, V., Warrick, J. I., Wu, X. R., Kaag, M., Raman, J. D. & Degraff, D. J., May 2 2019, In : International journal of molecular sciences. 20, 10, 2599.

Research output: Contribution to journalArticle

Open Access
Histone Deacetylases
bladder
Polymerase chain reaction
Urinary Bladder Neoplasms
cancer
1 Citation (Scopus)

Circulating microRNAs in plasma among men with low-grade and high-grade prostate cancer at prostate biopsy

McDonald, A. C., Vira, M., Walter, V., Shen, J., Raman, J. D., Sanda, M. G., Patil, D. & Taioli, E., Jun 15 2019, In : Prostate. 79, 9, p. 961-968 8 p.

Research output: Contribution to journalArticle

MicroRNAs
Prostatic Neoplasms
Biopsy
Neoplasm Grading
Prostate-Specific Antigen
1 Citation (Scopus)
Open Access
Clinical Trials
Survival
Neoplasms
Therapeutics
Insurance
Open Access
Students
evaluation
student
Nonparametric Statistics
Medical Students
2 Citations (Scopus)

Gene Expression Subtype Predicts Nodal Metastasis and Survival in Human Papillomavirus–Negative Head and Neck Cancer

Zevallos, J. P., Mazul, A. L., Walter, V. & Hayes, D. N., Jan 2019, In : Laryngoscope. 129, 1, p. 154-161 8 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Squamous Cell Carcinoma
Neoplasm Metastasis
Gene Expression
Survival
2 Citations (Scopus)

GPx3 supports ovarian cancer progression by manipulating the extracellular redox environment

Worley, B. L., Kim, Y. S., Mardini, J., Zaman, R., Leon, K. E., Vallur, P. G., Nduwumwami, A., Warrick, J. I., Timmins, P. F., Kesterson, J. P., Phaëton, R., Lee, N. Y., Walter, V., Endres, L., Mythreye, K., Aird, K. M. & Hempel, N., Jul 2019, In : Redox Biology. 25, 101051.

Research output: Contribution to journalArticle

Glutathione Peroxidase
Ovarian Neoplasms
Oxidation-Reduction
Ascites
Adenocarcinoma

Hypermethylation of FOXA1 and allelic loss of PTEN drive squamous differentiation and promote heterogeneity in bladder cancer

Osei-Amponsa, V., Buckwalter, J. M., Shuman, L., Zheng, Z., Yamashita, H., Walter, V., Wildermuth, T., Ellis-Mohl, J., Liu, C., Warrick, J. I., Shantz, L. M., Feehan, R. P., Al-Ahmadie, H., Mendelsohn, C., Raman, J. D., Kaestner, K. H., Wu, X. R. & DeGraff, D. J., Jan 1 2019, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Loss of Heterozygosity
Urinary Bladder Neoplasms
Urothelium
Inborn Genetic Diseases
DNA

Impact of HFE variants and sex in lung cancer

Lee, S. Y., Walter, V., Zhu, J., Salzberg, A. C., Liu, D. J. & Connor, J. R., Jan 1 2019, In : PloS one. 14, 12, e0226821.

Research output: Contribution to journalArticle

Open Access
lung neoplasms
Lung Neoplasms
Genes
Atlases
gender
21 Citations (Scopus)

Intratumoral Heterogeneity of Bladder Cancer by Molecular Subtypes and Histologic Variants [Figure presented]

Warrick, J. I., Sjödahl, G., Kaag, M., Raman, J. D., Merrill, S., Shuman, L., Chen, G., Walter, V. & DeGraff, D. J., Jan 2019, In : European Urology. 75, 1, p. 18-22 5 p.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Neoplasms
Histology
Selection Bias
Carcinoma
Papillary Carcinoma
Recurrence
Neoplasms
Proportional Hazards Models
Neoplasm Grading
2 Citations (Scopus)

Molecular characterization of tumors meeting diagnostic criteria for the non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP)

Pool, C., Walter, V., Bann, D., Goldenberg, D., Broach, J., Hennessy, M., Cottrill, E., Washburn, E., Williams, N., Crist, H., Imamura, Y. & Warrick, J., Mar 11 2019, In : Virchows Archiv. 474, 3, p. 341-351 11 p.

Research output: Contribution to journalArticle

Thyroid Neoplasms
Factor IX
Neoplasms
Adenoma
RNA Sequence Analysis

Opioid Analgesics Do Not Improve Abdominal Pain or Quality of Life in Crohn’s Disease

Coates, M. D., Seth, N., Clarke, K., Abdul-Baki, H., Mahoney, N., Walter, V., Regueiro, M. D., Ramos-Rivers, C., Koutroubakis, I. E., Bielefeldt, K. & Binion, D. G., Jan 1 2019, (Accepted/In press) In : Digestive Diseases and Sciences.

Research output: Contribution to journalArticle

Crohn Disease
Abdominal Pain
Opioid Analgesics
Quality of Life
Pain

Repression of transcription factor AP-2 alpha by PPARγ reveals a novel transcriptional circuit in basal-squamous bladder cancer

Yamashita, H., Kawasawa, Y. I., Shuman, L., Zheng, Z., Tran, T., Walter, V., Warrick, J. I., Chen, G., Al-Ahmadie, H., Kaag, M., Wong, P. K., Raman, J. D. & DeGraff, D. J., Dec 1 2019, In : Oncogenesis. 8, 12, 69.

Research output: Contribution to journalArticle

Open Access
Transcription Factor AP-2
PPAR alpha
Peroxisome Proliferator-Activated Receptors
Activating Transcription Factor 2
Urinary Bladder Neoplasms
2018
2 Citations (Scopus)
Malpractice
Climate
Thyroid Neoplasms
climate
incidence
5 Citations (Scopus)

Frequent HPV-independent p16/INK4A overexpression in head and neck cancer

Lechner, M., Chakravarthy, A. R., Walter, V., Masterson, L., Feber, A., Jay, A., Weinberger, P. M., McIndoe, R. A., Forde, C. T., Chester, K., Kalavrezos, N., O'Flynn, P., Forster, M., Jones, T. M., Vaz, F. M., Hayes, D. N. & Fenton, T. R., Aug 2018, In : Oral Oncology. 83, p. 32-37 6 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Squamous Cell Neoplasms
Protein Array Analysis
Head
Mutation
38 Citations (Scopus)

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 194-212.e6

Research output: Contribution to journalArticle

Squamous Cell Carcinoma
MicroRNAs
Mutation
Epithelial Cells
Squamous Cell Neoplasms
1 Citation (Scopus)
Open Access
Inflammatory Bowel Diseases
Phenotype
Voltage-Gated Sodium Channels
Abdominal Pain
Single Nucleotide Polymorphism
31 Citations (Scopus)

Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors

George, J., Walter, V., Peifer, M., Alexandrov, L. B., Seidel, D., Leenders, F., Maas, L., Müller, C., Dahmen, I., Delhomme, T. M., Ardin, M., Leblay, N., Byrnes, G., Sun, R., De Reynies, A., McLeer-Florin, A., Bosco, G., Malchers, F., Menon, R., Altmüller, J. & 42 others, Becker, C., Nürnberg, P., Achter, V., Lang, U., Schneider, P. M., Bogus, M., Soloway, M. G., Wilkerson, M. D., Cun, Y., McKay, J. D., Moro-Sibilot, D., Brambilla, C. G., Lantuejoul, S., Lemaitre, N., Soltermann, A., Weder, W., Tischler, V., Brustugun, O. T., Lund-Iversen, M., Helland, Å., Solberg, S., Ansén, S., Wright, G., Solomon, B., Roz, L., Pastorino, U., Petersen, I., Clement, J. H., Sänger, J., Wolf, J., Vingron, M., Zander, T., Perner, S., Travis, W. D., Haas, S. A., Olivier, M., Foll, M., Büttner, R., Hayes, D. N., Brambilla, E., Fernandez-Cuesta, L. & Thomas, R. K., Dec 1 2018, In : Nature communications. 9, 1, 1048.

Research output: Contribution to journalArticle

Neuroendocrine Carcinoma
Large Cell Carcinoma
Neuroendocrine Tumors
lungs
Tumors
1 Citation (Scopus)

MVisAGe identifies concordant and discordant genomic alterations of driver genes in squamous tumors

Walter, V., Du, Y., Danilova, L., Hayward, M. C. & Hayes, D. N., Jun 15 2018, In : Cancer Research. 78, 12, p. 3375-3385 11 p.

Research output: Contribution to journalArticle

Oncogenes
Gene Expression
DNA Copy Number Variations
Genes
Neoplasms
23 Citations (Scopus)

The Integrated Genomic Landscape of Thymic Epithelial Tumors

The Cancer Genome Atlas Network, Feb 12 2018, In : Cancer Cell. 33, 2, p. 244-258.e10

Research output: Contribution to journalArticle

Thymoma
Myasthenia Gravis
Autoantigens
Aneuploidy
Mutation
2017
2 Citations (Scopus)

Altered molecular profile in thyroid cancers from patients affected by the Three Mile Island nuclear accident

Goldenberg, D., Russo, M., Houser, K., Crist, H., Derr, J. B., Walter, V., Warrick, J. I., Sheldon, K. E., Broach, J. & Bann, D. V., Jul 2017, In : Laryngoscope. 127, p. S1-S9

Research output: Contribution to journalArticle

Radioactive Hazard Release
Thyroid Neoplasms
Islands
Gene Fusion
Radiation-Induced Neoplasms
5 Citations (Scopus)

Autologous reconstitution of human cancer and immune system in vivo

Fu, J., Sen, R., Masica, D. L., Karchin, R., Pardoll, D., Walter, V., Hayes, D. N., Chung, C. H. & Kim, Y. J., Jan 1 2017, In : Oncotarget. 8, 2, p. 2053-2068 16 p.

Research output: Contribution to journalArticle

Immune System
Tumor Microenvironment
Neoplasms
Human Trafficking
Tumor-Infiltrating Lymphocytes
147 Citations (Scopus)

Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma

Fishbein, L., Leshchiner, I., Walter, V., Danilova, L., Robertson, A. G., Johnson, A. R., Lichtenberg, T. M., Murray, B. A., Ghayee, H. K., Else, T., Ling, S., Jefferys, S. R., de Cubas, A. A., Wenz, B., Korpershoek, E., Amelio, A. L., Makowski, L., Rathmell, W. K., Gimenez-Roqueplo, A. P., Giordano, T. J. & 187 others, Asa, S. L., Tischler, A. S., Akbani, R., Ally, A., Amar, L., Arachchi, H., Auchus, R. J., Auman, J. T., Baertsch, R., Balasundaram, M., Balu, S., Bartsch, D. K., Baudin, E., Bauer, T., Beaver, A., Benz, C., Beroukhim, R., Beuschlein, F., Bodenheimer, T., Boice, L., Bowen, J., Bowlby, R., Brooks, D., Carlsen, R., Carter, S., Cassol, C. A., Cherniack, A. D., Chin, L., Cho, J., Chuah, E., Chudamani, S., Cope, L., Crain, D., Curley, E., de Krijger, R. R., Demchok, J. A., Deutschbein, T., Dhalla, N., Dimmock, D., Dinjens, W. N. M., Eng, C., Eschbacher, J., Fassnacht, M., Felau, I., Feldman, M., Ferguson, M. L., Fiddes, I., Frazer, S., Gabriel, S. B., Gardner, J., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Geurts, J., Goldman, M., Graim, K., Gupta, M., Haan, D., Hahner, S., Hantel, C., Haussler, D., Hayes, D. N., Heiman, D. I., Hoadley, K. A., Holt, R. A., Hoyle, A. P., Huang, M., Hunt, B., Hutter, C. M., Jones, S. J. M., Jones, C. D., Kasaian, K., Kebebew, E., Kim, J., Kimes, P., Knijnenburg, T., Lander, E., Lawrence, M. S., Lechan, R., Lee, D., Leraas, K. M., Lerario, A., Lin, P., Liu, J., LiVolsi, V. A., Lolla, L., Lotan, Y., Lu, Y., Ma, Y., Maison, N., Mallery, D., Mannelli, M., Marquard, J., Marra, M. A., Matthew, T., Mayo, M., Méatchi, T., Meng, S., Merino, M. J., Mete, O., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Morozova, O., Morris, S., Mose, L. E., Mungall, A. J., Naresh, R., Nathanson, K. L., Newton, Y., Ng, S., Ni, Y., Noble, M. S., Nwariaku, F., Pacak, K., Parker, J. S., Paul, E., Penny, R., Perou, C. M., Perou, A. H., Pihl, T., Powers, J., Rabaglia, J., Radenbaugh, A., Ramirez, N. C., Rao, A., Riester, A., Roach, J., Sadeghi, S., Saksena, G., Salama, S., Saller, C., Sandusky, G., Sbiera, S., Schein, J. E., Schumacher, S. E., Shelton, C., Shelton, T., Sheth, M., Shi, Y., Shih, J., Shmulevich, I., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Sokolov, A., Soloway, M. G., Sougnez, C., Stuart, J., Sun, C., Swatloski, T., Tam, A., Tan, D., Tarnuzzer, R., Tarvin, K., Thiessen, N., Thorne, L. B., Timmers, H. J., Tse, K., Uzunangelov, V., van Berkel, A., Veluvolu, U., Vicha, A., Voet, D., Waldmann, J., Wan, Y., Wang, Z., Wang, T. S., Weaver, J., Weinstein, J. N., Weismann, D., Wilkerson, M. D., Wise, L., Wong, T., Wong, C., Wu, Y., Yang, L., Zelinka, T., Zenklusen, J. C., Zhang, J. J., Zhang, W., Zhu, J., Zinzindohoué, F. & Zmuda, E., Feb 13 2017, In : Cancer Cell. 31, 2, p. 181-193 13 p.

Research output: Contribution to journalArticle

Paraganglioma
Pheochromocytoma
Gene Fusion
Genes
Precision Medicine
27 Citations (Scopus)

Genetic evolution of uveal melanoma guides the development of an inflammatory microenvironment

Gezgin, G., Dogrusöz, M., van Essen, T. H., Kroes, W. G. M., Luyten, G. P. M., van der Velden, P. A., Walter, V., Verdijk, R. M., van Hall, T., van der Burg, S. H. & Jager, M. J., Jul 1 2017, In : Cancer Immunology, Immunotherapy. 66, 7, p. 903-912 10 p.

Research output: Contribution to journalArticle

Molecular Evolution
T-Lymphocytes
Chromosomes, Human, Pair 3
Chromosomes
Macrophages
80 Citations (Scopus)

Integrated Molecular Characterization of Uterine Carcinosarcoma

Cherniack, A. D., Shen, H., Walter, V., Stewart, C., Murray, B. A., Bowlby, R., Hu, X., Ling, S., Soslow, R. A., Broaddus, R. R., Zuna, R. E., Robertson, G., Laird, P. W., Kucherlapati, R., Mills, G. B., Akbani, R., Ally, A., Auman, J. T., Balasundaram, M., Balu, S. & 130 others, Baylin, S. B., Beroukhim, R., Bodenheimer, T., Bogomolniy, F., Boice, L., Bootwalla, M. S., Bowen, J., Broaddus, R., Brooks, D., Carlsen, R., Cho, J., Chuah, E., Chudamani, S., Cibulskis, K., Cline, M., Dao, F., David, M., Demchok, J. A., Dhalla, N., Dowdy, S., Felau, I., Ferguson, M. L., Frazer, S., Frick, J., Gabriel, S., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Gupta, M., Haussler, D., Hayes, D. N., Heiman, D. I., Hess, J., Hoadley, K. A., Hoffmann, R., Holt, R. A., Hoyle, A. P., Huang, M., Hutter, C. M., Jefferys, S. R., Jones, S. J. M., Jones, C. D., Kanchi, R. S., Kandoth, C., Kasaian, K., Kerr, S., Kim, J., Lai, P. H., Lander, E., Lawrence, M. S., Lee, D., Leraas, K. M., Leshchiner, I., Levine, D. A., Lichtenberg, T. M., Lin, P., Liu, J., Liu, W., Liu, Y., Lolla, L., Lu, Y., Ma, Y., Maglinte, D. T., Marra, M. A., Mayo, M., Meng, S., Meyerson, M., Mieczkowski, P. A., Moore, R. A., Mose, L. E., Mungall, A. J., Mungall, K., Naresh, R., Noble, M. S., Olvera, N., Parker, J. S., Perou, C. M., Perou, A. H., Pihl, T., Radenbaugh, A. J., Ramirez, N. C., Rathmell, W. K., Roach, J., Robertson, A. G., Sadeghi, S., Saksena, G., Salvesen, H. B., Schein, J. E., Schumacher, S. E., Sheth, M., Shi, Y., Shih, J., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Soloway, M. G., Sougnez, C., Sun, C., Tam, A., Tan, D., Tarnuzzer, R., Thiessen, N., Thorne, L. B., Tse, K., Tseng, J., Van Den Berg, D. J., Veluvolu, U., Verhaak, R. G. W., Voet, D., von Bismarck, A., Wan, Y., Wang, Z., Wang, C., Weinstein, J. N., Weisenberger, D. J., Wilkerson, M. D., Winterhoff, B., Wise, L., Wong, T., Wu, Y., Yang, L., Zenklusen, J. C., Zhang, J. J., Zhang, H., Zhang, W., Zhu, J. C., Zmuda, E. & Zhang, J., Mar 13 2017, In : Cancer Cell. 31, 3, p. 411-423 13 p.

Research output: Contribution to journalArticle

Carcinosarcoma
Epithelial-Mesenchymal Transition
Epigenomics
Proteomics
Mutation
130 Citations (Scopus)

Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

Robertson, A. G., Shih, J., Yau, C., Gibb, E. A., Oba, J., Mungall, K. L., Hess, J. M., Uzunangelov, V., Walter, V., Danilova, L., Lichtenberg, T. M., Kucherlapati, M., Kimes, P. K., Tang, M., Penson, A., Babur, O., Akbani, R., Bristow, C. A., Hoadley, K. A., Iype, L. & 150 others, Chang, M. T., Abdel-Rahman, M. H., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., Benz, C., Beroukhim, R., Birol, I., Bodenheimer, T., Bowen, J., Bowlby, R., Brooks, D., Carlsen, R., Cebulla, C. M., Cherniack, A. D., Chin, L., Cho, J., Chuah, E., Chudamani, S., Cibulskis, C., Cibulskis, K., Cope, L., Coupland, S. E., Defreitas, T., Demchok, J. A., Desjardins, L., Dhalla, N., Esmaeli, B., Felau, I., Ferguson, M. L., Frazer, S., Gabriel, S. B., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Gershenwald, J. E., Getz, G., Griewank, K. G., Grimm, E. A., Hayes, D. N., Hegde, A. M., Heiman, D. I., Helsel, C., Hobensack, S., Holt, R. A., Hoyle, A. P., Hu, X., Hutter, C. M., Jager, M. J., Jefferys, S. R., Jones, C. D., Jones, S. J. M., Kandoth, C., Kasaian, K., Kim, J., Kucherlapati, R., Lander, E., Lawrence, M. S., Lazar, A. J., Lee, S., Leraas, K. M., Lin, P., Liu, J., Liu, W., Lolla, L., Lu, Y., Ma, Y., Mahadeshwar, H. S., Mariani, O., Marra, M. A., Mayo, M., Meier, S., Meng, S., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Mose, L. E., Mungall, A. J., Murray, B. A., Naresh, R., Noble, M. S., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Perou, C. M., Pihl, T., Pilarski, R., Protopopov, A., Radenbaugh, A., Rai, K., Ramirez, N. C., Ren, X., Reynolds, S. M., Roach, J., Roman-Roman, S., Roszik, J., Sadeghi, S., Saksena, G., Sastre, X., Schadendorf, D., Schein, J. E., Schoenfield, L., Schumacher, S. E., Seidman, J., Seth, S., Sethi, G., Sheth, M., Shi, Y., Shields, C., Shmulevich, I., Simons, J. V., Singh, A. D., Sipahimalani, P., Skelly, T., Sofia, H., Soloway, M. G., Song, X., Stern, M. H., Stuart, J., Sun, Q., Sun, H., Tam, A., Tan, D., Tang, J., Tarnuzzer, R., Taylor, B. S., Thiessen, N., Thorsson, V., Tse, K., Veluvolu, U., Verhaak, R. G. W., Voet, D., Wan, Y., Wang, Z., Weinstein, J. N., Wilkerson, M. D., Williams, M. D., Wise, L., Woodman, S. E., Wong, T., Wu, Y., Yang, L., Yang, L., Zenklusen, J. C., Zhang, J., Zhang, H. & Zmuda, E., Aug 14 2017, In : Cancer Cell. 32, 2, p. 204-220.e15

Research output: Contribution to journalArticle

Monosomy
DNA Methylation
Mutation
Uveal melanoma
Neoplasms
16 Citations (Scopus)

MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma

Bailey, S. T., Smith, A. M., Kardos, J., Wobker, S. E., Wilson, H. L., Krishnan, B., Saito, R., Lee, H. J., Zhang, J., Eaton, S. C., Williams, L. A., Manocha, U., Peters, D. J., Pan, X., Carroll, T. J., Felsher, D. W., Walter, V., Zhang, Q., Parker, J. S., Yeh, J. J. & 3 others, Moffitt, R. A., Leung, J. Y. & Kim, W. Y., Jun 8 2017, In : Nature communications. 8, 15770.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Tumors
tumors
cancer
Chemical activation
13 Citations (Scopus)

Targeting a non-oncogene addiction to the ATR/CHK1 axis for the treatment of small cell lung cancer

Doerr, F., George, J., Schmitt, A., Beleggia, F., Rehkämper, T., Hermann, S., Walter, V., Weber, J. P., Thomas, R. K., Wittersheim, M., Büttner, R., Persigehl, T. & Christian Reinhardt, H., Dec 1 2017, In : Scientific reports. 7, 1, 15511.

Research output: Contribution to journalArticle

Small Cell Lung Carcinoma
Therapeutics
Cell Cycle Checkpoints
Lung Neoplasms
Drug Therapy
2016
26 Citations (Scopus)

FOXA1, GATA3 and PPARIγ Cooperate to drive luminal subtype in bladder cancer: A molecular analysis of established human cell lines

Warrick, J. I., Walter, V., Yamashita, H., Chung, E., Shuman, L., Amponsa, V. O., Zheng, Z., Chan, W., Whitcomb, T. L., Yue, F., Iyyanki, T., Kawasawa, Y. I., Kaag, M., Guo, W., Raman, J. D., Park, J. S. & Degraff, D. J., Dec 7 2016, In : Scientific reports. 6, 38531.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Cell Line
Basal Cell Neoplasms
Encyclopedias
Neoplasms
2015
22 Citations (Scopus)

Combined targeted DNA sequencing in Non-Small Cell Lung Cancer (NSCLC) using UNCseq and NGScopy, and RNA sequencing using UNCqeR for the detection of genetic aberrations in NSCLC

Zhao, X., Wang, A., Walter, V., Patel, N. M., Eberhard, D. A., Hayward, M. C., Salazar, A. H., Jo, H., Soloway, M. G., Wilkerson, M. D., Parker, J. S., Yin, X., Zhang, G., Siegel, M. B., Rosson, G. B., Earp, H. S., Sharpless, N. E., Gulley, M. L., Weck, K. E., Hayes, D. N. & 1 others, Moschos, S. J., Jun 15 2015, In : PloS one. 10, 6, e0129280.

Research output: Contribution to journalArticle

RNA Sequence Analysis
lung neoplasms
Aberrations
DNA Sequence Analysis
Non-Small Cell Lung Carcinoma
1261 Citations (Scopus)

Comprehensive genomic characterization of head and neck squamous cell carcinomas

The Cancer Genome Atlas Network, Jan 29 2015, In : Nature. 517, 7536, p. 576-582 7 p.

Research output: Contribution to journalArticle

Mutation
Neoplasms
TNF Receptor-Associated Factor 3
cdc Genes
Atlases

Consistent testing for recurrent genomic aberrations

Walter, V., Wright, F. A. & Nobel, A. B., Dec 1 2015, In : Biometrika. 102, 4, p. 783-796 14 p.

Research output: Contribution to journalArticle

Markov Chains
Genome-Wide Association Study
Fourier Analysis
DNA Methylation
Aberrations
959 Citations (Scopus)

Genomic Classification of Cutaneous Melanoma

The Cancer Genome Atlas Network, Jun 20 2015, In : Cell. 161, 7, p. 1681-1696 16 p.

Research output: Contribution to journalArticle

Melanoma
Skin
T-cells
Lymphocytes
Pathology
2014
50 Citations (Scopus)

BRG1/SMARCA4 inactivation promotes non-small cell lung cancer aggressiveness by altering chromatin organization

Orvis, T., Hepperla, A., Walter, V., Song, S., Simon, J., Parker, J., Wilkerson, M. D., Desai, N., Major, M. B., Hayes, D. N., Davis, I. J. & Weissman, B., Nov 15 2014, In : Cancer Research. 74, 22, p. 6486-6498 13 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Chromatin
Chromatin Assembly and Disassembly
Nucleosomes
Gene Expression
59 Citations (Scopus)

Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination

Hast, B. E., Cloer, E. W., Goldfarb, D., Li, H., Siesser, P. F., Yan, F., Walter, V., Zheng, N., Hayes, D. N. & Major, M. B., Feb 1 2014, In : Cancer Research. 74, 3, p. 808-817 10 p.

Research output: Contribution to journalArticle

Ubiquitination
Mutation
Neoplasms
Ubiquitin-Protein Ligases
Proteasome Endopeptidase Complex
13 Citations (Scopus)

Gene silencing associated with SWI/SNF complex loss during NSCLC development

Song, S., Walter, V., Karaca, M., Li, Y., Bartlett, C. S., Smiraglia, D. J., Serber, D., Sproul, C. D., Plass, C., Zhang, J., Hayes, D. N., Zheng, Y. & Weissman, B. E., Apr 2014, In : Molecular Cancer Research. 12, 4, p. 560-570 11 p.

Research output: Contribution to journalArticle

Gene Silencing
Non-Small Cell Lung Carcinoma
Methyltransferases
Epigenomics
Histone Deacetylase Inhibitors
63 Citations (Scopus)

Hedgehog-GLI signaling inhibition suppresses tumor growth in squamous lung cancer

Huang, L., Walter, V., Hayes, D. N. & Onaitis, M., Jan 1 2014, In : Clinical Cancer Research. 20, 6, p. 1566-1575 10 p.

Research output: Contribution to journalArticle

Hedgehogs
Squamous Cell Carcinoma
Lung Neoplasms
Lung
Growth
950 Citations (Scopus)

Integrated Genomic Characterization of Papillary Thyroid Carcinoma

Agrawal, N., Akbani, R., Aksoy, B. A., Ally, A., Arachchi, H., Asa, S. L., Auman, J. T., Balasundaram, M., Balu, S., Baylin, S. B., Behera, M., Bernard, B., Beroukhim, R., Bishop, J. A., Black, A. D., Bodenheimer, T., Boice, L., Bootwalla, M. S., Bowen, J., Bowlby, R. & 223 others, Bristow, C. A., Brookens, R., Brooks, D., Bryant, R., Buda, E., Butterfield, Y. S. N., Carling, T., Carlsen, R., Carter, S. L., Carty, S. E., Chan, T. A., Chen, A. Y., Cherniack, A. D., Cheung, D., Chin, L., Cho, J., Chu, A., Chuah, E., Cibulskis, K., Ciriello, G., Clarke, A., Clayman, G. L., Cope, L., Copland, J. A., Covington, K., Danilova, L., Davidsen, T., Demchok, J. A., DiCara, D., Dhalla, N., Dhir, R., Dookran, S. S., Dresdner, G., Eldridge, J., Eley, G., El-Naggar, A. K., Eng, S., Fagin, J. A., Fennell, T., Ferris, R. L., Fisher, S., Frazer, S., Frick, J., Gabriel, S. B., Ganly, I., Gao, J., Garraway, L. A., Gastier-Foster, J. M., Getz, G., Gehlenborg, N., Ghossein, R., Gibbs, R. A., Giordano, T. J., Gomez-Hernandez, K., Grimsby, J., Gross, B., Guin, R., Hadjipanayis, A., Harper, H. A., Hayes, D. N., Heiman, D. I., Herman, J. G., Hoadley, K. A., Hofree, M., Holt, R. A., Hoyle, A. P., Huang, F. W., Huang, M., Hutter, C. M., Ideker, T., Iype, L., Jacobsen, A., Jefferys, S. R., Jones, C. D., Jones, S. J. M., Kasaian, K., Kebebew, E., Khuri, F. R., Kim, J., Kramer, R., Kreisberg, R., Kucherlapati, R., Kwiatkowski, D. J., Ladanyi, M., Lai, P. H., Laird, P. W., Lander, E., Lawrence, M. S., Lee, D., Lee, E., Lee, S., Lee, W., Leraas, K. M., Lichtenberg, T. M., Lichtenstein, L., Lin, P., Ling, S., Liu, J., Liu, W., Liu, Y., LiVolsi, V. A., Lu, Y., Ma, Y., Mahadeshwar, H. S., Marra, M. A., Mayo, M., McFadden, D. G., Meng, S., Meyerson, M., Mieczkowski, P. A., Miller, M., Mills, G., Moore, R. A., Mose, L. E., Mungall, A. J., Murray, B. A., Nikiforov, Y. E., Noble, M. S., Ojesina, A. I., Owonikoko, T. K., Ozenberger, B. A., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Paull, E. O., Pedamallu, C. S., Perou, C. M., Prins, J. F., Protopopov, A., Ramalingam, S. S., Ramirez, N. C., Ramirez, R., Raphael, B. J., Rathmell, W. K., Ren, X., Reynolds, S. M., Rheinbay, E., Ringel, M. D., Rivera, M., Roach, J., Robertson, A. G., Rosenberg, M. W., Rosenthal, M., Sadeghi, S., Saksena, G., Sander, C., Santoso, N., Schein, J. E., Schultz, N., Schumacher, S. E., Seethala, R. R., Seidman, J., Senbabaoglu, Y., Seth, S., Sharpe, S., Shaw, K. R. M., Shen, J. P., Shen, R., Sherman, S., Sheth, M., Shi, Y., Shmulevich, I., Sica, G. L., Simons, J. V., Sinha, R., Sipahimalani, P., Smallridge, R. C., Sofia, H. J., Soloway, M. G., Song, X., Sougnez, C., Stewart, C., Stojanov, P., Stuart, J. M., Sumer, S. O., Sun, Y., Tabak, B., Tam, A., Tan, D., Tang, J., Tarnuzzer, R., Taylor, B. S., Thiessen, N., Thorne, L., Thorsson, V., Tuttle, R. M., Umbricht, C. B., Van Den Berg, D. J., Vandin, F., Veluvolu, U., Verhaak, R. G. W., Vinco, M., Voet, D., Walter, V., Wang, Z., Waring, S., Weinberger, P. M., Weinhold, N., Weinstein, J. N., Weisenberger, D. J., Wheeler, D., Wilkerson, M. D., Wilson, J., Williams, M., Winer, D. A., Wise, L., Wu, J., Xi, L., Xu, A. W., Yang, L., Yang, L., Zack, T. I., Zeiger, M. A., Zeng, D., Zenklusen, J. C., Zhao, N., Zhang, H., Zhang, J., Zhang, J., Zhang, W., Zmuda, E. & Zou, L., Oct 23 2014, In : Cell. 159, 3, p. 676-690 15 p.

Research output: Contribution to journalArticle

Thyroid Neoplasms
Factor IX
Methylation
Pathology
Gene expression
46 Citations (Scopus)

Integrated RNA and DNA sequencing improves mutation detection in low purity tumors

Wilkerson, M. D., Cabanski, C. R., Sun, W., Hoadley, K. A., Walter, V., Mose, L. E., Troester, M. A., Hammerman, P. S., Parker, J. S., Perou, C. M. & Hayes, D. N., 2014, In : Nucleic acids research. 42, 13, p. e107

Research output: Contribution to journalArticle

RNA Sequence Analysis
Exome
DNA Sequence Analysis
Mutation
DNA
2013
134 Citations (Scopus)

Molecular Subtypes in Head and Neck Cancer Exhibit Distinct Patterns of Chromosomal Gain and Loss of Canonical Cancer Genes

Walter, V., Yin, X., Wilkerson, M. D., Cabanski, C. R., Zhao, N., Du, Y., Ang, M. K., Hayward, M. C., Salazar, A. H., Hoadley, K. A., Fritchie, K., Sailey, C. G., Weissler, M. C., Shockley, W. W., Zanation, A. M., Hackman, T., Thorne, L. B., Funkhouser, W. D., Muldrew, K. L., Olshan, A. F. & 4 others, Randell, S. H., Wright, F. A., Shores, C. G. & Hayes, D. N., Feb 22 2013, In : PloS one. 8, 2, e56823.

Research output: Contribution to journalArticle

Papillomaviridae
papilloma
Neoplasm Genes
squamous cell carcinoma
Head and Neck Neoplasms
2012
2015 Citations (Scopus)

Comprehensive genomic characterization of squamous cell lung cancers

Hammerman, P. S., Voet, D., Lawrence, M. S., Voet, D., Jing, R., Cibulskis, K., Sivachenko, A., Stojanov, P., McKenna, A., Lander, E. S., Gabriel, S., Getz, G., Imielinski, M., Helman, E., Hernandez, B., Pho, N. H., Meyerson, M., Chu, A., Hye-Chun, J. E., Mungall, A. J. & 316 others, Pleasance, E., Robertson, A. G., Sipahimalani, P., Stoll, D., Balasundaram, M., Birol, I., Butterfield, Y. S. N., Chuah, E., Coope, R. J. N., Corbett, R., Dhalla, N., Guin, R., He, A., Hirst, C., Hirst, M., Holt, R. A., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Mungall, K., Nip, K. M., Olshen, A., Schein, J. E., Slobodan, J. R., Tam, A., Thiessen, N., Varhol, R., Zeng, T., Zhao, Y., Jones, S. J. M., Marra, M. A., Saksena, G., Cherniack, A. D., Schumacher, S. E., Tabak, B., Carter, S. L., Nguyen, H., Onofrio, R. C., Crenshaw, A., Ardlie, K., Beroukhim, R., Winckler, W., Protopopov, A., Zhang, J., Hadjipanayis, A., Lee, S., Xi, R., Yang, L., Ren, X., Zhang, H., Shukla, S., Chen, P. C., Haseley, P., Lee, E., Chin, L., Park, P. J., Kucherlapati, R., Socci, N. D., Liang, Y., Schultz, N., Borsu, L., Lash, A. E., Viale, A., Sander, C., Ladanyi, M., Auman, J. T., Hoadley, K. A., Wilkerson, M. D., Shi, Y., Liquori, C., Meng, S., Li, L., Turman, Y. J., Topal, M. D., Tan, D., Waring, S., Buda, E., Walsh, J., Jones, C. D., Mieczkowski, P. A., Singh, D., Wu, J., Gulabani, A., Dolina, P., Bodenheimer, T., Hoyle, A. P., Simons, J. V., Soloway, M. G., Stuart, J., Mose, L. E., Jefferys, S. R., Balu, S., O'Connor, B. D., Chiang, D., Liu, J., Chiang, D. Y., Hayes, D. N., Perou, C. M., Cope, L., Weisenberger, D., Danilova, L., Weisenberger, D. J., Maglinte, D. T., Pan, F., Van Den Berg, D. J., Triche, T., Herman, J. G., Baylin, S. B., Laird, P. W., Noble, M., Gehlenborg, N., DiCara, D., Zhang, J., Wu, C. J., Liu, S. Y., Zou, L., Lin, P., Cho, J., Nazaire, M. D., Robinson, J., Thorvaldsdottir, H., Mesirov, J., Sinha, R., Ciriello, G., Cerami, E., Gross, B., Jacobsen, A., Gao, J., Aksoy, B. A., Weinhold, N., Ramirez, R., Taylor, B. S., Antipin, Y., Reva, B., Mo, Q., Seshan, V., Paik, P. K., Akbani, R., Zhang, N., Broom, B. M., Casasent, T., Unruh, A., Wakefield, C., Cason, R. C., Baggerly, K. A., Weinstein, J. N., Haussler, D., Benz, C. C., Stuart, J. M., Zhu, J., Szeto, C., Scott, G. K., Yau, C., Ng, S., Goldstein, T., Waltman, P., Sokolov, A., Collisson, E., Ellrott, K., Collisson, E. A., Zerbino, D., Ma, S., Craft, B., Du, Y., Cabanski, C., Walter, V., Marron, J. S., Liu, Y., Wang, K., Prins, J. F., Creighton, C. J., Zhang, Y., Travis, W. D., Rekhtman, N., Yi, J., Aubry, M. C., Cheney, R., Dacic, S., Flieder, D., Funkhouser, W., Illei, P., Myers, J., Tsao, M. S., Penny, R., Mallery, D., Shelton, T., Hatfield, M., Morris, S., Yena, P., Shelton, C., Sherman, M., Paulauskis, J., Govindan, R., Azodo, I., Beer, D., Bose, R., Byers, L. A., Carbone, D., Chang, L. W., Chun, E., Ding, L., Heymach, J., Ida, C., Johnson, B., Jurisica, I., Kaufman, J., Kosari, F., Kwiatkowski, D., Maher, C. A., Pao, W., Peifer, M., Robertson, G., Rusch, V., Siegfried, J., Sougnez, C., Thomas, R. K., Tomaszek, S., Vaske, C., Wheeler, D., Wigle, D. A., Wilks, C., Zhang, J. J., Jensen, M. A., Sfeir, R., Kahn, A. B., Chu, A. L., Kothiyal, P., Wang, Z., Snyder, E. E., Pontius, J., Pihl, T. D., Backus, M., Walton, J., Baboud, J., Berton, D. L., Nicholls, M. C., Srinivasan, D., Raman, R., Girshik, S., Kigonya, P. A., Alonso, S., Sanbhadti, R. N., Barletta, S. P., Greene, J. M., Pot, D. A., Bandarchi-Chamkhaleh, B., Boyd, J., Weaver, J., Azodo, I. A., Tomaszek, S. C., Yang, P., Brock, M. V., Rogers, K., Rutledge, M., Brown, T., Lee, B., Shin, J., Trusty, D., Dhir, R., Siegfried, J. M., Potapova, O., Fedosenko, K. V., Zakowski, M., Nemirovich-Danchenko, E., Iacocca, M. V., Brown, J., Rabeno, B., Czerwinski, C., Petrelli, N., Fan, Z., Todaro, N., Eckman, J., Rathmell, W. K., Thorne, L. B., Huang, M., Boice, L., Hill, A., Curley, E., Morrison, C., Gaudioso, C., Bartlett, J. M. S., Kodeeswaran, S., Zanke, B., Sekhon, H., David, K., Juhl, H., Le, X. V., Kohl, B., Thorp, R., Tien, N. V., Bang, N. V., Sussman, H., Phu, B. D., Hajek, R., Hung, N. P., Khan, K. Z., Muley, T., Mills Shaw, K. R., Sheth, M., Yang, L., Demchok, J. A., Davidsen, T., Buetow, K., Eley, G., Ferguson, M., Dillon, L. A. L., Schaefer, C., Guyer, M. S., Ozenberger, B. A., Palchik, J. D., Peterson, J., Sofia, H. J., Thomson, E., Johnson, B. E. & Shen, R., Sep 27 2012, In : Nature. 489, 7417, p. 519-525 7 p.

Research output: Contribution to journalArticle

Squamous Cell Neoplasms
Lung Neoplasms
Mutation
Neoplasms
Genes
96 Citations (Scopus)

Differential pathogenesis of lung adenocarcinoma subtypes involving sequence mutations, copy number, chromosomal instability, and methylation

Wilkerson, M. D., Yin, X., Walter, V., Zhao, N., Cabanski, C. R., Hayward, M. C., Miller, C. R., Socinski, M. A., Parsons, A. M., Thorne, L. B., Haithcock, B. E., Veeramachaneni, N. K., Funkhouser, W. K., Randell, S. H., Bernard, P. S., Perou, C. M. & Hayes, D. N., May 10 2012, In : PloS one. 7, 5, e36530.

Research output: Contribution to journalArticle

Chromosomal Instability
Methylation
adenocarcinoma
methylation
Tumors
2011
24 Citations (Scopus)

DiNAMIC: A method to identify recurrent DNA copy number aberrations in tumors

Walter, V., Nobel, A. B. & Wright, F. A., Mar 1 2011, In : Bioinformatics. 27, 5, p. 678-685 8 p., btq717.

Research output: Contribution to journalArticle

Aberrations
Aberration
Tumors
Tumor
Cancer
29 Citations (Scopus)

High XRCC1 protein expression is associated with poorer survival in patients with head and neck squamous cell carcinoma

Ang, M. K., Patel, M. R., Yin, X. Y., Sundaram, S., Fritchie, K., Zhao, N., Liu, Y., Freemerman, A. J., Wilkerson, M. D., Walter, V., Weissler, M. C., Shockley, W. W., Couch, M. E., Zanation, A. M., Hackman, T., Chera, B. S., Harris, S. L., Miller, C. R., Thorne, L. B., Hayward, M. C. & 5 others, Funkhouser, W. K., Olshan, A. F., Shores, C. G., Makowski, L. & Hayes, D. N., Oct 15 2011, In : Clinical Cancer Research. 17, 20, p. 6542-6552 11 p.

Research output: Contribution to journalArticle

Survival
Proteins
Carcinoma, squamous cell of head and neck
Radiation
Cricetulus
13 Citations (Scopus)

Metabolic control of resting hemispheric cerebral blood flow is oxidative, not glycolytic

Powers, W. J., Videen, T. O., Markham, J., Walter, V. & Perlmutter, J. S., May 1 2011, In : Journal of Cerebral Blood Flow and Metabolism. 31, 5, p. 1223-1228 6 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Glucose
Oxygen
Brain
Multivariate Analysis