Projects per year
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Research interests
Dr. Wei Li’s laboratory is interested in studying intercellular interactions during tissue homeostasis and determining how de-regulated interactions among cells promote cell transformation and tumor progression. His research integrates molecular, cellular and biochemical approaches in combination with mouse tumorigenesis models. Currently, Dr. Li’s laboratory focuses on elucidating the regulation and function of the Hippo tumor suppressor pathway in brain tumors. The goal of Dr. Li’s research is to find molecular targets and biomarkers for cancer therapy.
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THE ROLE OF NONO IN TAZ-DRIVEN GLIOMA MALIGNANT TRANSFORMATION
9/1/18 → 7/31/23
Project: Research project
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The mechanism and function of cell competition in tumors
Li, W. & Li, W.
8/19/15 → 7/31/18
Project: Research project
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Tumor necrosis: A synergistic consequence of metabolic stress and inflammation
Yee, P. P. & Li, W., Jul 2021, In: BioEssays. 43, 7, 2100029.Research output: Contribution to journal › Article › peer-review
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L-type Ca2+ channel blockers promote vascular remodeling through activation of STIM proteins
Johnson, M. T., Gudlur, A., Zhang, X., Xin, P., Emrich, S. M., Yoast, R. E., Courjaret, R., Nwokonko, R. M., Li, W., Hempel, N., Machaca, K., Gill, D. L., Hogan, P. G. & Trebak, M., Jul 21 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 29, p. 17369-17380 12 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
NEDD4L-mediated Merlin ubiquitination facilitates Hippo pathway activation
Wei, Y., Yee, P. P., Liu, Z., Zhang, L., Guo, H., Zheng, H., Anderson, B., Gulley, M. & Li, W., Dec 3 2020, In: EMBO Reports. 21, 12, e50642.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression
Yee, P. P., Wei, Y., Kim, S. Y., Lu, T., Chih, S. Y., Lawson, C., Tang, M., Liu, Z., Anderson, B., Thamburaj, K., Young, M. M., Aregawi, D. G., Glantz, M. J., Zacharia, B. E., Specht, C. S., Wang, H. G. & Li, W., Dec 1 2020, In: Nature communications. 11, 1, 5424.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis
Liu, Z., Yee, P. P., Wei, Y., Liu, Z., Imamura, Y. & Li, W., Mar 1 2019, In: Journal of Cell Science. 132, 5, jcs225714.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations