Projects per year
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Research interests
Dr. Wei Li’s laboratory is interested in studying intercellular interactions during tissue homeostasis and determining how de-regulated interactions among cells promote cell transformation and tumor progression. His research integrates molecular, cellular and biochemical approaches in combination with mouse tumorigenesis models. Currently, Dr. Li’s laboratory focuses on elucidating the regulation and function of the Hippo tumor suppressor pathway in brain tumors. The goal of Dr. Li’s research is to find molecular targets and biomarkers for cancer therapy.
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THE ROLE OF NONO IN TAZ-DRIVEN GLIOMA MALIGNANT TRANSFORMATION
9/1/18 → 7/31/23
Project: Research project
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IDENTIFICATION AND CHARACTERIZATION OF A NOVEL POSTTRANSLATIONAL MODIFICATION OF MERLIN IN TUMOR SUPPRESSION
Congressionally Directed Medical Research Programs
7/1/18 → 6/30/21
Project: Research project
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Calcium, an Emerging Intracellular Messenger for the Hippo Pathway Regulation
Wei, Y. & Li, W., Jun 29 2021, In: Frontiers in Cell and Developmental Biology. 9, 694828.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations -
Fascin promotes lung cancer growth and metastasis by enhancing glycolysis and PFKFB3 expression
Lin, S., Li, Y., Wang, D., Huang, C., Marino, D., Bollt, O., Wu, C., Taylor, M. D., Li, W., DeNicola, G. M., Hao, J., Singh, P. K. & Yang, S., Oct 10 2021, In: Cancer Letters. 518, p. 230-242 13 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Paraspeckle Protein NONO Promotes TAZ Phase Separation in the Nucleus to Drive the Oncogenic Transcriptional Program
Wei, Y., Luo, H., Yee, P. P., Zhang, L., Liu, Z., Zheng, H., Zhang, L., Anderson, B., Tang, M., Huang, S. & Li, W., Dec 22 2021, In: Advanced Science. 8, 24, 2102653.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Tumor necrosis: A synergistic consequence of metabolic stress and inflammation
Yee, P. P. & Li, W., Jul 2021, In: BioEssays. 43, 7, 2100029.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
L-type Ca2+ channel blockers promote vascular remodeling through activation of STIM proteins
Johnson, M. T., Gudlur, A., Zhang, X., Xin, P., Emrich, S. M., Yoast, R. E., Courjaret, R., Nwokonko, R. M., Li, W., Hempel, N., Machaca, K., Gill, D. L., Hogan, P. G. & Trebak, M., Jul 21 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 29, p. 17369-17380 12 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations