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Personal profile

Research interests

Dr. Wei Li’s laboratory is interested in studying intercellular interactions during tissue homeostasis and determining how de-regulated interactions among cells promote cell transformation and tumor progression. His research integrates molecular, cellular and biochemical approaches in combination with mouse tumorigenesis models. Currently, Dr. Li’s laboratory focuses on elucidating the regulation and function of the Hippo tumor suppressor pathway in brain tumors. The goal of Dr. Li’s research is to find molecular targets and biomarkers for cancer therapy.

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  • 4 Similar Profiles
Neurofibromin 2 Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Neurofibromatosis 2 Medicine & Life Sciences
Genes Chemical Compounds
Tumors Chemical Compounds
Cells Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2018 2023

Research Output 2006 2019

  • 905 Citations
  • 12 h-Index
  • 15 Article
  • 4 Review article
5 Citations (Scopus)

Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis

Liu, Z., Yee, P. P., Wei, Y., Liu, Z., Imamura, Y. & Li, W., Mar 1 2019, In : Journal of Cell Science. 132, 5, jcs225714.

Research output: Contribution to journalArticle

Open Access
Glioma
Carcinogenesis
Neoplasms
Glioblastoma
Growth
8 Citations (Scopus)

Induction of store-operated calcium entry (SOCE) suppresses glioblastoma growth by inhibiting the Hippo pathway transcriptional coactivators YAP/TAZ

Liu, Z., Wei, Y., Zhang, L., Yee, P. P., Johnson, M., Zhang, X., Gulley, M., Atkinson, J. M., Trebak, M., Wang, H-G. & Li, W., Jan 3 2019, In : Oncogene. 38, 1, p. 120-139 20 p.

Research output: Contribution to journalArticle

Protein Kinase C beta
Glioblastoma
Amlodipine
Calcium
Growth
4 Citations (Scopus)

Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells

Zhang, L., Cheng, F., Wei, Y., Zhang, L., Guo, D., Wang, B. & Li, W., Apr 11 2019, In : Oncogene. 38, 15, p. 2788-2799 12 p.

Research output: Contribution to journalArticle

Glioma
Radiation
Catenins
Growth
Glioblastoma

YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis

Pajtler, K. W., Wei, Y., Okonechnikov, K., Silva, P. B. G., Vouri, M., Zhang, L., Brabetz, S., Sieber, L., Gulley, M., Mauermann, M., Wedig, T., Mack, N., Imamura Kawasawa, Y., Sharma, T., Zuckermann, M., Andreiuolo, F., Holland, E., Maass, K., Körkel-Qu, H., Liu, H. K. & 13 others, Sahm, F., Capper, D., Bunt, J., Richards, L. J., Jones, D. T. W., Korshunov, A., Chavez, L., Lichter, P., Hoshino, M., Pfister, S. M., Kool, M., Li, W. & Kawauchi, D., Dec 1 2019, In : Nature communications. 10, 1, 3914.

Research output: Contribution to journalArticle

Open Access
NFI Transcription Factors
Ependymoma
subgroups
Carcinogenesis
Fusion reactions
2 Citations (Scopus)

2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis

Fisher, M. J., Belzberg, A. J., de Blank, P., De Raedt, T., Elefteriou, F., Ferner, R. E., Giovannini, M., Harris, G. J., Kalamarides, M., Karajannis, M. A., Kim, A. R., Lázaro, C., Le, L. Q., Li, W., Listernick, R., Martin, S., Morrison, H., Pasmant, E., Ratner, N., Schorry, E. & 7 others, Ullrich, N. J., Viskochil, D., Weiss, B., Widemann, B. C., Zhu, Y., Bakker, A. & Serra, E., May 2018, In : American Journal of Medical Genetics, Part A. 176, 5, p. 1258-1269 12 p.

Research output: Contribution to journalArticle

Neurofibromatosis 2
Neurofibromatosis 1
Neurofibromatoses
Neurilemmoma
Plexiform Neurofibroma