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Research interests
Dr. Wei Li’s laboratory is interested in studying intercellular interactions during tissue homeostasis and determining how de-regulated interactions among cells promote cell transformation and tumor progression. His research integrates molecular, cellular and biochemical approaches in combination with mouse tumorigenesis models. Currently, Dr. Li’s laboratory focuses on elucidating the regulation and function of the Hippo tumor suppressor pathway in brain tumors. The goal of Dr. Li’s research is to find molecular targets and biomarkers for cancer therapy.
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Projects 2018 2023
- 1 Active
THE ROLE OF NONO IN TAZ-DRIVEN GLIOMA MALIGNANT TRANSFORMATION
9/1/18 → 7/31/23
Project: Research project
Research Output 2006 2019
Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis
Liu, Z., Yee, P. P., Wei, Y., Liu, Z., Imamura, Y. & Li, W., Mar 1 2019, In : Journal of Cell Science. 132, 5, jcs225714.Research output: Contribution to journal › Article
Induction of store-operated calcium entry (SOCE) suppresses glioblastoma growth by inhibiting the Hippo pathway transcriptional coactivators YAP/TAZ
Liu, Z., Wei, Y., Zhang, L., Yee, P. P., Johnson, M., Zhang, X., Gulley, M., Atkinson, J. M., Trebak, M., Wang, H-G. & Li, W., Jan 3 2019, In : Oncogene. 38, 1, p. 120-139 20 p.Research output: Contribution to journal › Article
Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells
Zhang, L., Cheng, F., Wei, Y., Zhang, L., Guo, D., Wang, B. & Li, W., Apr 11 2019, In : Oncogene. 38, 15, p. 2788-2799 12 p.Research output: Contribution to journal › Article
2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis
Fisher, M. J., Belzberg, A. J., de Blank, P., De Raedt, T., Elefteriou, F., Ferner, R. E., Giovannini, M., Harris, G. J., Kalamarides, M., Karajannis, M. A., Kim, A. R., Lázaro, C., Le, L. Q., Li, W., Listernick, R., Martin, S., Morrison, H., Pasmant, E., Ratner, N., Schorry, E. & 7 others, , May 1 2018, In : American Journal of Medical Genetics, Part A. 176, 5, p. 1258-1269 12 p.Research output: Contribution to journal › Article
Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets
Chen, Y. B., Xu, J., Skanderup, A. J., Dong, Y., Brannon, A. R., Wang, L., Won, H. H., Wang, P. I., Nanjangud, G. J., Jungbluth, A. A., Li, W., Ojeda, V., Hakimi, A. A., Voss, M. H., Schultz, N., Motzer, R. J., Russo, P., Cheng, E. H., Giancotti, F. G., Lee, W. & 4 others, , Oct 7 2016, In : Nature communications. 7, 13131.Research output: Contribution to journal › Article