Projects per year
Personal profile
Research interests
Dr. Wei Li’s laboratory is interested in studying intercellular interactions during tissue homeostasis and determining how de-regulated interactions among cells promote cell transformation and tumor progression. His research integrates molecular, cellular and biochemical approaches in combination with mouse tumorigenesis models. Currently, Dr. Li’s laboratory focuses on elucidating the regulation and function of the Hippo tumor suppressor pathway in brain tumors. The goal of Dr. Li’s research is to find molecular targets and biomarkers for cancer therapy.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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THE ROLE OF NONO IN TAZ-DRIVEN GLIOMA MALIGNANT TRANSFORMATION
9/1/18 → 7/31/23
Project: Research project
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Temporal radiographic and histological study of necrosis development in a mouse glioblastoma model
Yee, P. P., Wang, J., Chih, S. Y., Aregawi, D. G., Glantz, M. J., Zacharia, B. E., Thamburaj, K. & Li, W., Oct 14 2022, In: Frontiers in Oncology. 12, 993649.Research output: Contribution to journal › Article › peer-review
Open Access -
Calcium, an Emerging Intracellular Messenger for the Hippo Pathway Regulation
Wei, Y. & Li, W., Jun 29 2021, In: Frontiers in Cell and Developmental Biology. 9, 694828.Research output: Contribution to journal › Review article › peer-review
Open Access4 Scopus citations -
Fascin promotes lung cancer growth and metastasis by enhancing glycolysis and PFKFB3 expression
Lin, S., Li, Y., Wang, D., Huang, C., Marino, D., Bollt, O., Wu, C., Taylor, M. D., Li, W., DeNicola, G. M., Hao, J., Singh, P. K. & Yang, S., Oct 10 2021, In: Cancer Letters. 518, p. 230-242 13 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Paraspeckle Protein NONO Promotes TAZ Phase Separation in the Nucleus to Drive the Oncogenic Transcriptional Program
Wei, Y., Luo, H., Yee, P. P., Zhang, L., Liu, Z., Zheng, H., Zhang, L., Anderson, B., Tang, M., Huang, S. & Li, W., Dec 22 2021, In: Advanced Science. 8, 24, 2102653.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Tumor necrosis: A synergistic consequence of metabolic stress and inflammation
Yee, P. P. & Li, W., Jul 2021, In: BioEssays. 43, 7, 2100029.Research output: Contribution to journal › Article › peer-review
8 Scopus citations