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Wei Li, PhD

 https://orcid.org/0000-0001-5696-4309
    • 905 Citations
    • 12 h-Index
    20062023
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    Personal profile

    Research interests

    Dr. Wei Li’s laboratory is interested in studying intercellular interactions during tissue homeostasis and determining how de-regulated interactions among cells promote cell transformation and tumor progression. His research integrates molecular, cellular and biochemical approaches in combination with mouse tumorigenesis models. Currently, Dr. Li’s laboratory focuses on elucidating the regulation and function of the Hippo tumor suppressor pathway in brain tumors. The goal of Dr. Li’s research is to find molecular targets and biomarkers for cancer therapy.

    Fingerprint Dive into the research topics where Wei Li is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

    • 4 Similar Profiles
    Neurofibromin 2 Medicine & Life Sciences
    Ubiquitin-Protein Ligases Medicine & Life Sciences
    Carcinogenesis Medicine & Life Sciences
    Neoplasms Medicine & Life Sciences
    Neurofibromatosis 2 Medicine & Life Sciences
    Genes Chemical Compounds
    Tumors Chemical Compounds
    Cells Chemical Compounds

    Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Projects 2018 2023

    THE ROLE OF NONO IN TAZ-DRIVEN GLIOMA MALIGNANT TRANSFORMATION

    Li, W.

    9/1/18 → 7/31/23

    Project: Research project

    Research Output 2006 2019

    • 905 Citations
    • 12 h-Index
    • 15 Article
    • 4 Review article
    5 Citations (Scopus)

    Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis

    Liu, Z., Yee, P. P., Wei, Y., Liu, Z., Imamura, Y. & Li, W., Mar 1 2019, In : Journal of Cell Science. 132, 5, jcs225714.

    Research output: Contribution to journal › Article

    Open Access
    Glioma
    Carcinogenesis
    Neoplasms
    Glioblastoma
    Growth
    8 Citations (Scopus)

    Induction of store-operated calcium entry (SOCE) suppresses glioblastoma growth by inhibiting the Hippo pathway transcriptional coactivators YAP/TAZ

    Liu, Z., Wei, Y., Zhang, L., Yee, P. P., Johnson, M., Zhang, X., Gulley, M., Atkinson, J. M., Trebak, M., Wang, H-G. & Li, W., Jan 3 2019, In : Oncogene. 38, 1, p. 120-139 20 p.

    Research output: Contribution to journal › Article

    Protein Kinase C beta
    Glioblastoma
    Amlodipine
    Calcium
    Growth
    4 Citations (Scopus)

    Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells

    Zhang, L., Cheng, F., Wei, Y., Zhang, L., Guo, D., Wang, B. & Li, W., Apr 11 2019, In : Oncogene. 38, 15, p. 2788-2799 12 p.

    Research output: Contribution to journal › Article

    Glioma
    Radiation
    Catenins
    Growth
    Glioblastoma

    YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis

    Pajtler, K. W., Wei, Y., Okonechnikov, K., Silva, P. B. G., Vouri, M., Zhang, L., Brabetz, S., Sieber, L., Gulley, M., Mauermann, M., Wedig, T., Mack, N., Imamura Kawasawa, Y., Sharma, T., Zuckermann, M., Andreiuolo, F., Holland, E., Maass, K., Körkel-Qu, H., Liu, H. K. & 13 others, Sahm, F., Capper, D., Bunt, J., Richards, L. J., Jones, D. T. W., Korshunov, A., Chavez, L., Lichter, P., Hoshino, M., Pfister, S. M., Kool, M., Li, W. & Kawauchi, D., Dec 1 2019, In : Nature communications. 10, 1, 3914.

    Research output: Contribution to journal › Article

    Open Access
    NFI Transcription Factors
    Ependymoma
    subgroups
    Carcinogenesis
    Fusion reactions
    2 Citations (Scopus)

    2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis

    Fisher, M. J., Belzberg, A. J., de Blank, P., De Raedt, T., Elefteriou, F., Ferner, R. E., Giovannini, M., Harris, G. J., Kalamarides, M., Karajannis, M. A., Kim, A. R., Lázaro, C., Le, L. Q., Li, W., Listernick, R., Martin, S., Morrison, H., Pasmant, E., Ratner, N., Schorry, E. & 7 others, Ullrich, N. J., Viskochil, D., Weiss, B., Widemann, B. C., Zhu, Y., Bakker, A. & Serra, E., May 2018, In : American Journal of Medical Genetics, Part A. 176, 5, p. 1258-1269 12 p.

    Research output: Contribution to journal › Article

    Neurofibromatosis 2
    Neurofibromatosis 1
    Neurofibromatoses
    Neurilemmoma
    Plexiform Neurofibroma