William Lai

    • 431 Citations
    • 11 h-Index
    20052020

    Research output per year

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    Research Output

    • 431 Citations
    • 11 h-Index
    • 16 Article
    • 1 Conference contribution
    • 1 Letter
    • 1 Review article
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    Article
    2020

    Universal promoter scanning by Pol II during transcription initiation in Saccharomyces cerevisiae

    Qiu, C., Qiu, C., Jin, H., Vvedenskaya, I., Vvedenskaya, I., Llenas, J. A., Llenas, J. A., Zhao, T., Malik, I., Malik, I., Visbisky, A. M., Schwartz, S. L., Cui, P., Čabart, P., Čabart, P., Han, K. H., Lai, W. K. M., Lai, W. K. M., Metz, R. P., Johnson, C. D. & 7 others, Sze, S. H., Sze, S. H., Pugh, B. F., Pugh, B. F., Nickels, B. E., Nickels, B. E. & Kaplan, C. D., Jun 2 2020, In : Genome biology. 21, 1, 132.

    Research output: Contribution to journalArticle

    Open Access
    2019

    Characterizing protein-DNA binding event subtypes in ChIP-exo data

    Yamada, N., Lai, W. K. M., Farrell, N., Pugh, B. F. & Mahony, S., Mar 15 2019, In : Bioinformatics. 35, 6, p. 903-913 11 p.

    Research output: Contribution to journalArticle

    6 Scopus citations
    2018

    Genome-wide determinants of sequence-specific DNA binding of general regulatory factors

    Rossi, M. J., Lai, W. K. M. & Pugh, B. F., Apr 2018, In : Genome research. 28, 4, p. 497-508 12 p.

    Research output: Contribution to journalArticle

    9 Scopus citations

    Simplified ChIP-exo assays

    Rossi, M. J., Lai, W. K. M. & Pugh, B. F., Dec 1 2018, In : Nature communications. 9, 1, 2842.

    Research output: Contribution to journalArticle

    12 Scopus citations
    2017

    Genome-wide uniformity of human 'open' pre-initiation complexes

    Lai, W. K. M. & Pugh, B. F., Jan 2017, In : Genome research. 27, 1, p. 15-26 12 p.

    Research output: Contribution to journalArticle

    11 Scopus citations
    2015

    Chromatin mediation of a transcriptional memory effect in yeast

    Paul, E., Tirosh, I., Lai, W., Buck, M. J., Palumbo, M. J. & Morse, R. H., Jan 1 2015, In : G3: Genes, Genomes, Genetics. 5, 5, p. 829-838 10 p.

    Research output: Contribution to journalArticle

    Open Access
    7 Scopus citations
    2014

    Iron-responsive chromatin remodelling and MAPK signalling enhance adhesion in Candida albicans

    Puri, S., Lai, W. K. M., Rizzo, J. M., Buck, M. J. & Edgerton, M., Jul 2014, In : Molecular Microbiology. 93, 2, p. 291-305 15 p.

    Research output: Contribution to journalArticle

    11 Scopus citations
    2013

    An integrative approach to understanding the combinatorial histone code at functional elements

    Lai, W. K. M. & Buck, M. J., Sep 15 2013, In : Bioinformatics. 29, 18, p. 2231-2237 7 p.

    Research output: Contribution to journalArticle

    Open Access
    5 Scopus citations
    2012

    ArchTEx: Accurate extraction and visualization of next-generation sequence data

    Lai, W. K. M., Bard, J. E. & Buck, M. J., Apr 1 2012, In : Bioinformatics. 28, 7, p. 1021-1023 3 p., bts063.

    Research output: Contribution to journalArticle

    Open Access
    13 Scopus citations

    Chromatin architectures at fission yeast transcriptional promoters and replication origins

    Givens, R. M., Lai, W. K. M., Rizzo, J. M., Bard, J. E., Mieczkowski, P. A., Leatherwood, J., Huberman, J. A. & Buck, M. J., Aug 1 2012, In : Nucleic acids research. 40, 15, p. 7176-7189 14 p.

    Research output: Contribution to journalArticle

    Open Access
    28 Scopus citations
    2010

    ArchAlign: Coordinate-free chromatin alignment reveals novel architectures

    Lai, W. K. M. & Buck, M. J., Dec 23 2010, In : Genome biology. 11, 12, R126.

    Research output: Contribution to journalArticle

    Open Access
    11 Scopus citations

    Genome-wide search identifies Ccnd2 as a direct transcriptional target of Elf5 in mouse mammary gland

    Escamilla-Hernandez, R., Chakrabarti, R., Romano, R. A., Smalley, K., Zhu, Q., Lai, W., Halfon, M. S., Buck, M. J. & Sinha, S., Sep 10 2010, In : BMC Molecular Biology. 11, 68.

    Research output: Contribution to journalArticle

    Open Access
    12 Scopus citations
    2009

    Gene expression analysis of hepatic roles in cause and development of diabetes in Goto-Kakizaki rats

    Almon, R. R., DuBois, D. C., Lai, W., Xue, B., Nie, J. & Jusko, W. J., Jun 24 2009, In : Journal of Endocrinology. 200, 3, p. 331-346 16 p.

    Research output: Contribution to journalArticle

    Open Access
    46 Scopus citations
    2008

    Circadian variations in rat liver gene expression: Relationships to drug actions

    Almon, R. R., Yang, E., Lai, W., Androulakis, I. P., Dubois, D. C. & Jusko, W. J., Sep 2008, In : Journal of Pharmacology and Experimental Therapeutics. 326, 3, p. 700-716 17 p.

    Research output: Contribution to journalArticle

    Open Access
    47 Scopus citations

    Relationships between circadian rhythms and modulation of gene expression by glucocorticoids in skeletal muscle

    Almon, R. R., Yang, E., Lai, W., Androulakis, I. P., Ghimbovschi, S., Hoffman, E. P., Jusko, W. J. & DuBois, D. C., Oct 2008, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 295, 4, p. R1031-R1047

    Research output: Contribution to journalArticle

    48 Scopus citations
    2005

    Corticosteroid-regulated genes in rat kidney: Mining time series array data

    Almon, R. R., Lai, W., DuBois, D. C. & Jusko, W. J., Nov 1 2005, In : American Journal of Physiology - Endocrinology and Metabolism. 289, 5 52-5, p. E870-E882

    Research output: Contribution to journalArticle

    40 Scopus citations