Xuemei Huang, MD, PhD

    • 5306 Citations
    • 38 h-Index
    1974 …2022
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    Research Output 1990 2019

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    Article
    2019
    Open Access
    dopamine beta-monooxygenase
    Dopamine beta-Hydroxylase
    inflammatory bowel disease
    Polymorphism
    Inflammatory Bowel Diseases
    2 Citations (Scopus)

    Brain cholesterol metabolism and Parkinson's disease

    Huang, X., Sterling, N. W., Du, G., Sun, D., Stetter, C., Kong, L., Zhu, Y., Neighbors, J., Lewis, M., Chen, H., Hohl, R. & Mailman, R., Mar 1 2019, In : Movement Disorders. 34, 3, p. 386-395 10 p.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Cholesterol
    Brain
    Odds Ratio
    Logistic Models

    Higher Hippocampal Mean Diffusivity Values in Asymptomatic Welders

    Lee, E. Y., Flynn, M. R., Du, G., Lewis, M., Kong, L., Yanosky, J., Mailman, R. & Huang, X., Apr 1 2019, In : Toxicological Sciences. 168, 2, p. 486-496 11 p.

    Research output: Contribution to journalArticle

    Manganese
    Alzheimer Disease
    Hippocampus
    Brain
    Diffusion tensor imaging

    Individual preferences in motor coordination seen across the two hands: relations to movement stability and optimality

    de Freitas, P. B., Freitas, S. M. S. F., Lewis, M., Huang, X. & Latash, M., Jan 31 2019, In : Experimental Brain Research. 237, 1

    Research output: Contribution to journalArticle

    Hand
    Fingers
    Sensory Feedback
    Social Adjustment
    Task Performance and Analysis
    4 Citations (Scopus)

    Magnetic resonance T1w/T2w ratio: A parsimonious marker for Parkinson disease

    Du, G., Lewis, M., Sica, C., Kong, L. & Huang, X., Jan 1 2019, In : Annals of Neurology. 85, 1, p. 96-104 9 p.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Magnetic Resonance Spectroscopy
    Sensitivity and Specificity
    Area Under Curve
    Magnetic Resonance Imaging
    3 Citations (Scopus)

    Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells

    Sarkar, S., Rokad, D., Malovic, E., Luo, J., Harischandra, D. S., Jin, H., Anantharam, V., Huang, X., Lewis, M., Kanthasamy, A. & Kanthasamy, A. G., Jan 8 2019, In : Science Signaling. 12, 563, aat9900.

    Research output: Contribution to journalArticle

    Inflammasomes
    Manganese
    Exosomes
    Interleukin-1
    Neurodegenerative diseases
    5 Citations (Scopus)

    Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein

    Harischandra, D. S., Rokad, D., Neal, M. L., Ghaisas, S., Manne, S., Sarkar, S., Panicker, N., Zenitsky, G., Jin, H., Lewis, M., Huang, X., Anantharam, V., Kanthasamy, A. & Kanthasamy, A. G., Jan 1 2019, In : Science signaling. 12, 572, eaau4543.

    Research output: Contribution to journalArticle

    Synucleins
    Prions
    Manganese
    Agglomeration
    Exosomes

    Multimodal MRI evaluation of parkinsonian limbic pathologies

    Wang, E. W., Du, G., Lewis, M., Lee, E. Y., De Jesus, S., Kanekar, S., Kong, L. & Huang, X., Apr 1 2019, In : Neurobiology of Aging. 76, p. 194-200 7 p.

    Research output: Contribution to journalArticle

    Hippocampus
    Nucleus Accumbens
    Amygdala
    Magnetic Resonance Imaging
    Pathology
    1 Citation (Scopus)

    Quantitative analysis of multi-element synergy stabilizing performance: comparison of three methods with respect to their use in clinical studies

    Freitas, S. M. S. F., de Freitas, P. B., Lewis, M., Huang, X. & Latash, M., Feb 4 2019, In : Experimental Brain Research. 237, 2, p. 453-465 13 p.

    Research output: Contribution to journalArticle

    Analysis of Variance
    Computer Security
    Sensory Feedback
    Advisory Committees
    Fingers

    Ultrasensitive Detection of Aggregated α-Synuclein in Glial Cells, Human Cerebrospinal Fluid, and Brain Tissue Using the RT-QuIC Assay: New High-Throughput Neuroimmune Biomarker Assay for Parkinsonian Disorders

    Manne, S., Kondru, N., Hepker, M., Jin, H., Anantharam, V., Lewis, M., Huang, X., Kanthasamy, A. & Kanthasamy, A. G., Sep 15 2019, In : Journal of Neuroimmune Pharmacology. 14, 3, p. 423-435 13 p.

    Research output: Contribution to journalArticle

    Synucleins
    Parkinsonian Disorders
    Neuroglia
    Parkinson Disease
    Cerebrospinal Fluid
    2018
    11 Citations (Scopus)

    Distinct progression pattern of susceptibility MRI in the substantia nigra of Parkinson's patients

    Du, G., Lewis, M., Sica, C., He, L., Connor, J., Kong, L., Mailman, R. & Huang, X., Sep 1 2018, In : Movement Disorders. 33, 9, p. 1423-1431 9 p.

    Research output: Contribution to journalArticle

    Substantia Nigra
    Control Groups
    Parkinson Disease
    Longitudinal Studies
    Pars Reticulata
    1 Citation (Scopus)

    HFE Genotype Restricts the Response to Paraquat in a Mouse Model of Neurotoxicity

    Nixon, A. M., Meadowcroft, M., Neely, E. B., Snyder, A., Purnell, C. J., Wright, J., Lamendella, R., Nandar, W., Huang, X. & Connor, J., May 1 2018, In : Journal of neurochemistry. 145, 4, p. 299-311 13 p.

    Research output: Contribution to journalArticle

    Paraquat
    Genotype
    Substantia Nigra
    Tyrosine 3-Monooxygenase
    Iron
    Open Access
    Inflammatory Bowel Diseases
    Phenotype
    Voltage-Gated Sodium Channels
    Abdominal Pain
    Single Nucleotide Polymorphism
    17 Citations (Scopus)

    Projection of the prevalence of Parkinson's disease in the coming decades: Revisited

    Rossi, A., Berger, K., Chen, H., Leslie, D., Mailman, R. & Huang, X., Jan 1 2018, In : Movement Disorders. 33, 1, p. 156-159 4 p.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Smoking
    Resource Allocation
    Censuses
    Population
    4 Citations (Scopus)

    Stability of steady hand force production explored across spaces and methods of analysis

    de Freitas, P. B., Freitas, S. M. S. F., Lewis, M., Huang, X. & Latash, M., Jun 1 2018, In : Experimental Brain Research. 236, 6, p. 1545-1562 18 p.

    Research output: Contribution to journalArticle

    Fingers
    Hand
    Advisory Committees
    Young Adult
    Equipment and Supplies
    11 Citations (Scopus)

    Susceptibility MRI captures nigral pathology in patients with parkinsonian syndromes

    Lewis, M., Du, G., Baccon, J., Snyder, A., Murie, B., Cooper, F., Stetter, C., Kong, L., Sica, C., Mailman, R., Connor, J. & Huang, X., Sep 1 2018, In : Movement Disorders. 33, 9, p. 1432-1439 8 p.

    Research output: Contribution to journalArticle

    Synucleins
    Parkinsonian Disorders
    Substantia Nigra
    Pathology
    Iron
    4 Citations (Scopus)

    Systemic effects of deep brain stimulation on synergic control in Parkinson's disease

    Falaki, A., Jo, H. J., Lewis, M., O'Connell, B., De Jesus, S., McInerney, J., Huang, X. & Latash, M., Jun 1 2018, In : Clinical Neurophysiology. 129, 6, p. 1320-1332 13 p.

    Research output: Contribution to journalArticle

    Deep Brain Stimulation
    Fingers
    Parkinson Disease
    Muscles
    Advisory Committees
    1 Citation (Scopus)

    Welding-related brain and functional changes in welders with chronic and low-level exposure

    Lee, E. Y., Flynn, M. R., Lewis, M., Mailman, R. & Huang, X., Jan 1 2018, In : NeuroToxicology. 64, p. 50-59 10 p.

    Research output: Contribution to journalArticle

    Welding
    Manganese
    Brain
    Basal Ganglia
    Magnetic resonance imaging
    2017
    6 Citations (Scopus)

    Association of neurobehavioral performance with R2* in the caudate nucleus of asymptomatic welders

    Lee, E. Y., Eslinger, P., Flynn, M. R., Wagner, D., Du, G., Lewis, M., Kong, L., Mailman, R. & Huang, X., Jan 1 2017, In : NeuroToxicology. 58, p. 66-74 9 p.

    Research output: Contribution to journalArticle

    Welding
    Caudate Nucleus
    Manganese
    Brain
    Neuropsychological Tests
    9 Citations (Scopus)

    Changes in Multidigit Synergies and Their Feed-Forward Adjustments in Multiple Sclerosis

    Jo, H. J., Mattos, D., Lucassen, E., Huang, X. & Latash, M., Mar 4 2017, In : Journal of motor behavior. 49, 2, p. 218-228 11 p.

    Research output: Contribution to journalArticle

    Multiple Sclerosis
    Fingers
    Advisory Committees
    2 Citations (Scopus)

    Circulating cholesterol levels may link to the factors influencing Parkinson's Risk

    Zhang, L., Wang, X., Wang, M., Sterling, N. W., Du, G., Lewis, M., Yao, T., Mailman, R., Li, R. & Huang, X., Sep 27 2017, In : Frontiers in Neurology. 8, SEP, 501.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Cholesterol
    LDL Cholesterol
    Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Propensity Score
    5 Citations (Scopus)
    Progressive Supranuclear Palsy
    Multiple System Atrophy
    Diffusion Tensor Imaging
    Parkinsonian Disorders
    Parkinson Disease
    4 Citations (Scopus)

    Cortical gray and subcortical white matter associations in Parkinson's disease

    Sterling, N. W., Du, G., Lewis, M., Swavely, S., Kong, L., Styner, M. & Huang, X., Jan 1 2017, In : Neurobiology of Aging. 49, p. 100-108 9 p.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Anisotropy
    Atrophy
    White Matter
    26 Citations (Scopus)

    Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing

    International Parkinson's Disease Genetics Consortium (IPGDC), Jan 30 2017, In : Genome biology. 18, 1, 22.

    Research output: Contribution to journalArticle

    Exome
    prioritization
    Parkinson disease
    Parkinson Disease
    gene
    9 Citations (Scopus)
    Parkinson Disease
    Muscles
    Dopamine Agents
    Pressure
    Pharmaceutical Preparations

    Evaluating the cost-effectiveness of an early detection of Parkinson's disease through innovative technology

    Muñoz, D. A., Kilinc, M. S., Nembhard, H. B., Tucker, C. S. & Huang, X., Apr 3 2017, In : Engineering Economist. 62, 2, p. 180-196 17 p.

    Research output: Contribution to journalArticle

    Cost effectiveness
    Disease
    costs
    Health
    Costs
    45 Citations (Scopus)

    Excessive burden of lysosomal storage disorder gene variants in Parkinson's disease

    Robak, L. A., Jansen, I. E., Rooij, J. V., Uitterlinden, A. G., Kraaij, R., Jankovic, J., Heutink, P., Shulman, J. M., Nalls, M. A., Plagnol, V., Hernandez, D. G., Sharma, M., Sheerin, U. M., Saad, M., Simón-Sánchez, J., Schulte, C., Lesage, S., Sveinbjörnsdóttir, S., Arepalli, S., Barker, R. & 120 others, Ben, Y., Berendse, H. W., Berg, D., Bhatia, K., de Bie, R. M. A., Biffi, A., Bloem, B., Bochdanovits, Z., Bonin, M., Bras, J. M., Brockmann, K., Brooks, J., Burn, D. J., Majounie, E., Charlesworth, G., Lungu, C., Chen, H., Chinnery, P. F., Chong, S., Clarke, C. E., Cookson, M. R., Cooper, J. M., Corvol, J. C., Counsell, C., Damier, P., Dartigues, J. F., Deloukas, P., Deuschl, G., Dexter, D. T., van Dijk, K. D., Dillman, A., Durif, F., Dürr, A., Edkins, S., Evans, J. R., Foltynie, T., Dong, J., Gardner, M., Gibbs, J. R., Goate, A., Gray, E., Guerreiro, R., Harris, C., van Hilten, J. J., Hofman, A., Hollenbeck, A., Holton, J., Hu, M., Huang, X., Wurster, I., Mätzler, W., Hudson, G., Hunt, S. E., Huttenlocher, J., Illig, T., Jónsson, P. V., Lambert, J. C., Langford, C., Lees, A., Lichtner, P., Limousin, P., Lopez, G., Lorenz, D., Lungu, C., McNeill, A., Moorby, C., Moore, M., Morris, H. R., Morrison, K. E., Escott-Price, V., Mudanohwo, E., O’sullivan, S. S., Pearson, J., Perlmutter, J. S., Pétursson, H., Pollak, P., Post, B., Potter, S., Ravina, B., Revesz, T., Riess, O., Rivadeneira, F., Rizzu, P., Ryten, M., Sawcer, S., Schapira, A., Scheffer, H., Shaw, K., Shoulson, I., Shulman, J., Sidransky, E., Smith, C., Spencer, C. C. A., Stefánsson, H., Bettella, F., Stockton, J. D., Strange, A., Talbot, K., Tanner, C. M., Tashakkori-Ghanbaria, A., Tison, F., Trabzuni, D., Traynor, B. J., Uitterlinden, A. G., Velseboer, D., Vidailhet, M., Walker, R., Warrenburg, B. V. D., Wickremaratchi, M., Williams, N., Williams-Gray, C. H., Winder-Rhodes, S., Stefánsson, K., Martinez, M., Wood, N. W., Hardy, J., Heutink, P., Brice, A., Gasser, T. & Singleton, A. B., Dec 1 2017, In : Brain. 140, 12, p. 3191-3203 13 p.

    Research output: Contribution to journalArticle

    Open Access
    Parkinson Disease
    Glucosylceramidase
    Genes
    Exome
    Disease Susceptibility
    12 Citations (Scopus)

    Free water improves detection of changes in the substantia nigra in parkinsonism: A multisite study

    Ofori, E., Krismer, F., Burciu, R. G., Pasternak, O., McCracken, J. L., Lewis, M., Du, G., McFarland, N. R., Okun, M. S., Poewe, W., Mueller, C., Gizewski, E. R., Schocke, M., Kremser, C., Li, H., Huang, X., Seppi, K. & Vaillancourt, D. E., Oct 1 2017, In : Movement Disorders. 32, 10, p. 1457-1464 8 p.

    Research output: Contribution to journalArticle

    Parkinsonian Disorders
    Substantia Nigra
    Water
    Anisotropy
    Diffusion Magnetic Resonance Imaging
    2 Citations (Scopus)

    Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans

    Dong, J., Wyss, A., Yang, J., Price, T. R., Nicolas, A., Nalls, M., Tranah, G., Franceschini, N., Xu, Z., Schulte, C., Alonso, A., Cummings, S. R., Fornage, M., Zaykin, D., Li, L., Huang, X., Kritchevsky, S., Liu, Y., Gasser, T., Wilson, R. S. & 9 others, De Jager, P. L., Singleton, A. B., Pinto, J. M., Harris, T., Mosley, T. H., Bennett, D. A., London, S., Yu, L. & Chen, H., Dec 1 2017, In : Molecular Neurobiology. 54, 10, p. 8021-8032 12 p.

    Research output: Contribution to journalArticle

    Smell
    Genome-Wide Association Study
    African Americans
    Neurodegenerative Diseases
    Prodromal Symptoms
    40 Citations (Scopus)

    Genome-wide pleiotropy between Parkinson disease and autoimmune diseases

    for the International Parkinson's Disease Genomics Consortium (IPDGC), United Kingdom Brain Expression Consortium (UKBEC) Investigators, North American Brain Expression Consortium (NABEC), Jul 1 2017, In : JAMA neurology. 74, 7, p. 780-792 13 p.

    Research output: Contribution to journalArticle

    Autoimmune Diseases
    Parkinson Disease
    Genome
    Genome-Wide Association Study
    Phenotype
    2 Citations (Scopus)

    Lateralized basal ganglia vulnerability to pesticide exposure in asymptomatic agricultural workers

    Lewis, M., Sterling, N. W., Du, G., Lee, E. Y., Shyu, G., Goldenberg, M., Allen, T., Stetter, C., Kong, L., Snipes, S. A., Jones, B. C., Chen, H., Mailman, R. & Huang, X., Jan 1 2017, In : Toxicological Sciences. 159, 1, p. 170-178 9 p.

    Research output: Contribution to journalArticle

    Diffusion tensor imaging
    Basal Ganglia
    Pesticides
    Corpus Striatum
    Globus Pallidus
    9 Citations (Scopus)

    Motor equivalence and structure of variance: multi-muscle postural synergies in Parkinson’s disease

    Falaki, A., Huang, X., Lewis, M. & Latash, M., Jul 1 2017, In : Experimental Brain Research. 235, 7, p. 2243-2258 16 p.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Muscles
    Analysis of Variance
    Posture
    Pharmaceutical Preparations
    5 Citations (Scopus)

    No genetic association between attention-deficit/hyperactivity disorder (ADHD) and Parkinson’s disease in nine ADHD candidate SNPs

    International Parkinson Disease Genomics Consortium members, Jun 1 2017, In : ADHD Attention Deficit and Hyperactivity Disorders. 9, 2, p. 121-127 7 p.

    Research output: Contribution to journalArticle

    Attention Deficit Disorder with Hyperactivity
    Single Nucleotide Polymorphism
    Parkinson Disease
    Norepinephrine Plasma Membrane Transport Proteins
    Receptor, Serotonin, 5-HT1B
    13 Citations (Scopus)

    Olfaction and incident Parkinson disease in US white and black older adults

    Chen, H., Shrestha, S., Huang, X., Jain, S., Guo, X., Tranah, G. J., Garcia, M. E., Satterfield, S., Phillips, C. & Harris, T. B., Oct 3 2017, In : Neurology. 89, 14, p. 1441-1447 7 p.

    Research output: Contribution to journalArticle

    Smell
    Parkinson Disease
    Confidence Intervals
    hydroquinone
    Information Storage and Retrieval
    4 Citations (Scopus)

    Positive association between Toxoplasma gondii IgG serointensity and current dysphoria/hopelessness scores in the Old Order Amish: A preliminary study

    Wadhawan, A., Dagdag, A., Duffy, A., Daue, M. L., Ryan, K. A., Brenner, L. A., Stiller, J. W., Pollin, T. I., Groer, M. W., Huang, X., Lowry, C. A., Mitchell, B. D. & Postolache, T. T., Dec 20 2017, In : Pteridines. 28, 3-4, p. 185-194 10 p.

    Research output: Contribution to journalArticle

    Amish
    Toxoplasma
    Immunoglobulin G
    Association reactions
    Anhedonia

    Predicting the multi-domain progression of Parkinson's disease: A Bayesian multivariate generalized linear mixed-effect model

    Wang, M., Li, Z., Lee, E. Y., Lewis, M., Zhang, L., Sterling, N. W., Wagner, D., Eslinger, P., Du, G. & Huang, X., Sep 25 2017, In : BMC Medical Research Methodology. 17, 1, 147.

    Research output: Contribution to journalArticle

    Parkinson Disease
    National Institute of Neurological Disorders and Stroke
    Organized Financing
    Statistical Models
    ROC Curve
    18 Citations (Scopus)

    Statins may facilitate Parkinson's disease: Insight gained from a large, national claims database

    Liu, G., Sterling, N. W., Kong, L., Lewis, M., Mailman, R., Chen, H., Leslie, D. & Huang, X., Jun 1 2017, In : Movement Disorders. 32, 6, p. 913-917 5 p.

    Research output: Contribution to journalArticle

    Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Parkinson Disease
    Databases
    Odds Ratio
    Prescriptions
    8 Citations (Scopus)

    The Prevalence of Anosmia and Associated Factors among U.S. Black and White Older Adults

    Dong, J., Pinto, J. M., Guo, X., Alonso, A., Tranah, G., Cauley, J. A., Garcia, M., Satterfield, S., Huang, X., Harris, T., Mosley, T. H. & Chen, H., Aug 1 2017, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 72, 8, p. 1080-1086 7 p.

    Research output: Contribution to journalArticle

    Olfaction Disorders
    Odds Ratio
    Confidence Intervals
    hydroquinone
    Health
    2016
    21 Citations (Scopus)

    Default mode network differences between rigidity- and tremor-predominant Parkinson's disease

    Karunanayaka, P., Lee, E. Y., Lewis, M., Sen, S., Eslinger, P., Yang, Q. & Huang, X., Aug 1 2016, In : Cortex. 81, p. 239-250 12 p.

    Research output: Contribution to journalArticle

    Tremor
    Parkinson Disease
    Parietal Lobe
    Gyrus Cinguli
    Hypokinesia
    18 Citations (Scopus)

    Effects of unilateral stroke on multi-finger synergies and their feed-forward adjustments

    Jo, H. J., Maenza, C., Good, D., Huang, X., Park, J., Sainburg, R. L. & Latash, M., Apr 5 2016, In : Neuroscience. 319, p. 194-205 12 p.

    Research output: Contribution to journalArticle

    Fingers
    Stroke
    Advisory Committees
    Hand
    14 Citations (Scopus)

    Finger force changes in the absence of visual feedback in patients with Parkinson's disease

    Jo, H. J., Ambike, S., Lewis, M., Huang, X. & Latash, M., Jan 1 2016, In : Clinical Neurophysiology. 127, 1, p. 684-692 9 p.

    Research output: Contribution to journalArticle

    Sensory Feedback
    Fingers
    Parkinson Disease
    Advisory Committees
    5 Citations (Scopus)

    Folded concave penalized learning in identifying multimodal MRI marker for Parkinson's disease

    Liu, H., Du, G., Zhang, L., Lewis, M., Wang, X., Yao, T., Li, R. & Huang, X., Aug 1 2016, In : Journal of Neuroscience Methods. 268, p. 1-6 6 p.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Learning
    Biomarkers
    Passive Cutaneous Anaphylaxis
    Logistic Models
    7 Citations (Scopus)

    Higher plasma LDL-cholesterol is associated with preserved executive and fine motor functions in Parkinson’s disease

    Sterling, N. W., Lichtenstein, M., Lee, E. Y., Lewis, M., Evans, A., Eslinger, P., Du, G., Gao, X., Chen, H., Kong, L. & Huang, X., Jan 1 2016, In : Aging and Disease. 7, 3, p. 237-245 9 p.

    Research output: Contribution to journalArticle

    Open Access
    LDL Cholesterol
    Parkinson Disease
    Cholesterol
    Executive Function
    Cognition
    20 Citations (Scopus)

    Impaired synergic control of posture in Parkinson's patients without postural instability

    Falaki, A., Huang, X., Lewis, M. & Latash, M., Feb 1 2016, In : Gait and Posture. 44, p. 209-215 7 p.

    Research output: Contribution to journalArticle

    Posture
    Parkinson Disease
    Muscles
    Electromyography
    Biomarkers
    10 Citations (Scopus)

    Increased R2* in the caudate nucleus of asymptomatic welders

    Lee, E. Y., Flynn, M. R., Du, G., Li, Y., Lewis, M., Herring, A. H., Buren, E. V., Buren, S. V., Kong, L., Fry, R. C., Snyder, A., Connor, J., Yang, Q., Mailman, R. & Huang, X., Apr 1 2016, In : Toxicological Sciences. 150, 2, p. 369-377 9 p., kfv331.

    Research output: Contribution to journalArticle

    Welding
    Caudate Nucleus
    Manganese
    Basal Ganglia
    Blood
    6 Citations (Scopus)

    Longitudinal T1 relaxation rate (R1) captures changes in short-term Mn exposure in welders

    Lewis, M., Flynn, M. R., Lee, E. Y., Van Buren, S., Van Buren, E., Du, G., Fry, R. C., Herring, A. H., Kong, L., Mailman, R. & Huang, X., Dec 1 2016, In : NeuroToxicology. 57, p. 39-44 6 p.

    Research output: Contribution to journalArticle

    Welding
    Blood
    Globus Pallidus
    Biomarkers
    Brain
    89 Citations (Scopus)

    Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy

    Lesage, S., Drouet, V., Majounie, E., Deramecourt, V., Jacoupy, M., Nicolas, A., Cormier-Dequaire, F., Hassoun, S. M., Pujol, C., Ciura, S., Erpapazoglou, Z., Usenko, T., Maurage, C. A., Sahbatou, M., Liebau, S., Ding, J., Bilgic, B., Emre, M., Erginel-Unaltuna, N., Guven, G. & 177 others, Tison, F., Tranchant, C., Vidailhet, M., Corvol, J. C., Krack, P., Leutenegger, A. L., Nalls, M. A., Hernandez, D. G., Heutink, P., Gibbs, J. R., Hardy, J., Wood, N. W., Gasser, T., Durr, A., Deleuze, J. F., Tazir, M., Destée, A., Lohmann, E., Kabashi, E., Singleton, A., Corti, O., Brice, A., Tison, F., Vidailhet, M., Corvol, J. C., Agid, Y., Anheim, M., Bonnet, A. M., Borg, M., Broussolle, E., Damier, P., Destée, A., Dürr, A., Durif, F., Krack, P., Klebe, S., Lohmann, E., Martinez, M., Pollak, P., Rascol, O., Tranchant, C., Vérin, M., Viallet, F., Lesage, S., Majounie, E., Tison, F., Vidailhet, M., Corvol, J. C., Nalls, M. A., Hernandez, D. G., Gibbs, J. R., Dürr, A., Arepalli, S., Barker, R. A., Ben-Shlomo, Y., Berg, D., Bettella, F., Bhatia, K., de Bie, R. M. A., Biffi, A., Bloem, B. R., Bochdanovits, Z., Bonin, M., Bras, J. M., Brockmann, K., Brooks, J., Burn, D. J., Charlesworth, G., Chen, H., Chinnery, P. F., Chong, S., Clarke, C. E., Cookson, M. R., Counsell, C., Damier, P., Dartigues, J. F., Deloukas, P., Deuschl, G., Dexter, D. T., van Dijk, K. D., Dillman, A., Dong, J., Durif, F., Edkins, S., Escott-Price, V., Evans, J. R., Foltynie, T., Gao, J., Gardner, M., Goate, A., Gray, E., Guerreiro, R., Harris, C., van Hilten, J. J., Hofman, A., Hollenbeck, A., Holmans, P., Holton, J., Hu, M., Huang, X., Huber, H., Hudson, G., Hunt, S. E., Huttenlocher, J., Illig, T., Jónsson, P. V., Kilarski, L. L., Jansen, I. E., Lambert, J. C., Langford, C., Lees, A., Lichtner, P., Limousin, P., Lopez, G., Lorenz, D., Lubbe, S., Lungu, C., Martinez, M., Mätzler, W., McNeill, A., Moorby, C., Moore, M., Morrison, K. E., Mudanohwo, E., O’sullivan, S. S., Owen, M. J., Pearson, J., Perlmutter, J. S., Pétursson, H., Plagnol, V., Pollak, P., Post, B., Potter, S., Ravina, B., Revesz, T., Riess, O., Rivadeneira, F., Rizzu, P., Ryten, M., Saad, M., Simón-Sánchez, J., Sawcer, S., Schapira, A., Scheffer, H., Schulte, C., Sharma, M., Shaw, K., Sheerin, U. M., Shoulson, I., Shulman, J., Sidransky, E., Spencer, C. C. A., Stefánsson, H., Stefánsson, K., Stockton, J. D., Strange, A., Talbot, K., Tanner, C. M., Tashakkori-Ghanbaria, A., Trabzuni, D., Traynor, B. J., Uitterlinden, A. G., Velseboer, D., Walker, R., Warrenburg, B. V. D., Wickremaratchi, M., Williams-Gray, C. H., Winder-Rhodes, S., Wurster, I., Williams, N., Morris, H. R., Heutink, P., Hardy, J., Wood, N. W., Gasser, T., Singleton, A. B. & Brice, A., Mar 3 2016, In : American Journal of Human Genetics. 98, 3, p. 500-513 14 p.

    Research output: Contribution to journalArticle

    Open Access
    Mitochondrial Degradation
    Parkinsonian Disorders
    Protein Transport
    Exome
    Consanguinity
    7 Citations (Scopus)

    Lower fractional anisotropy in the globus pallidus of asymptomatic welders, a marker for long-term welding exposure

    Lee, E. Y., Flynn, M. R., Du, G., Lewis, M., Herring, A. H., Van Buren, E., Van Buren, S., Kong, L., Mailman, R. & Huang, X., Sep 1 2016, In : Toxicological Sciences. 153, 1, p. 165-173 9 p., kfw116.

    Research output: Contribution to journalArticle

    Welding
    Globus Pallidus
    Anisotropy
    Manganese
    Basal Ganglia
    6 Citations (Scopus)

    Parkinson's disease biomarkers program brain imaging repository

    Ofori, E., Du, G., Babcock, D., Huang, X. & Vaillancourt, D. E., Jan 1 2016, In : NeuroImage. 124, p. 1120-1124 5 p.

    Research output: Contribution to journalArticle

    Neuroimaging
    Parkinson Disease
    Biomarkers
    Essential Tremor
    Information Dissemination
    66 Citations (Scopus)

    Quantitative susceptibility mapping of the midbrain in Parkinson's disease

    Du, G., Liu, T., Lewis, M., Kong, L., Wang, Y., Connor, J., Mailman, R. & Huang, X., Mar 1 2016, In : Movement Disorders. 31, 3, p. 317-324 8 p.

    Research output: Contribution to journalArticle

    Mesencephalon
    Parkinson Disease
    Iron
    Levodopa
    Magnetic Resonance Imaging