Xuemei Huang, MD, PhD

    • 5356 Citations
    • 38 h-Index
    1974 …2022
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    Research Output 1990 2019

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    Article
    2016
    66 Citations (Scopus)

    Quantitative susceptibility mapping of the midbrain in Parkinson's disease

    Du, G., Liu, T., Lewis, M., Kong, L., Wang, Y., Connor, J., Mailman, R. & Huang, X., Mar 1 2016, In : Movement Disorders. 31, 3, p. 317-324 8 p.

    Research output: Contribution to journalArticle

    Mesencephalon
    Parkinson Disease
    Iron
    Levodopa
    Magnetic Resonance Imaging
    20 Citations (Scopus)

    Serum 25-hydroxyvitamin D concentrations in Mid-adulthood and Parkinson's disease risk

    Shrestha, S., Lutsey, P. L., Alonso, A., Huang, X., Mosley, T. H. & Chen, H., Jul 1 2016, In : Movement Disorders. 31, 7, p. 972-978 7 p.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Serum
    Vitamin D
    Confidence Intervals
    Proportional Hazards Models
    8 Citations (Scopus)

    Stage-dependent loss of cortical gyrification as Parkinson disease "unfolds"

    Sterling, N. W., Wang, M., Zhang, L., Lee, E. Y., Du, G., Lewis, M., Styner, M. & Huang, X., Mar 22 2016, In : Neurology. 86, 12, p. 1143-1151 9 p.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Dementia
    Disease Progression
    Linear Models
    Pathology
    12 Citations (Scopus)

    Synergy as a new and sensitive marker of basal ganglia dysfunction: A study of asymptomatic welders

    Lewis, M., Lee, E. Y., Jo, H. J., Du, G., Park, J., Flynn, M. R., Kong, L., Latash, M. & Huang, X., Sep 1 2016, In : NeuroToxicology. 56, p. 76-85 10 p.

    Research output: Contribution to journalArticle

    Manganese
    Basal Ganglia
    Iron
    Anisotropy
    Neurodegenerative diseases
    8 Citations (Scopus)

    The key determinants to quality of life in Parkinson's disease patients: Results from the Parkinson's disease biomarker program (PDBP)

    He, L., Lee, E. Y., Sterling, N. W., Kong, L., Lewis, M., Du, G., Eslinger, P. & Huang, X., Jan 1 2016, In : Journal of Parkinson's Disease. 6, 3, p. 523-532 10 p.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Biomarkers
    Quality of Life
    Linear Models
    Regression Analysis
    30 Citations (Scopus)

    The NINDS Parkinson's disease biomarkers program

    Rosenthal, L. S., Drake, D., Alcalay, R. N., Babcock, D., Bowman, F. D., Chen-Plotkin, A., Dawson, T. M., Dewey, R. B., German, D. C., Huang, X., Landin, B., Mcauliffe, M., Petyuk, V. A., Scherzer, C. R., Hillaire-Clarke, C. S., Sieber, B. A., Sutherland, M., Tarn, C., West, A., Vaillancourt, D. & 2 others, Zhang, J. & Gwinn, K., Jun 1 2016, In : Movement Disorders. 31, 6, p. 915-923 9 p.

    Research output: Contribution to journalArticle

    National Institute of Neurological Disorders and Stroke
    Parkinson Disease
    Biomarkers
    Cerebrospinal Fluid
    Essential Tremor
    18 Citations (Scopus)

    The pattern of gray matter atrophy in Parkinson’s disease differs in cortical and subcortical regions

    Lewis, M., Du, G., Lee, E. Y., Nasralah, Z., Sterling, N. W., Zhang, L., Wagner, D., Kong, L., Tröster, A. I., Styner, M., Eslinger, P., Mailman, R. & Huang, X., Jan 1 2016, In : Journal of Neurology. 263, 1, p. 68-75 8 p.

    Research output: Contribution to journalArticle

    Atrophy
    Parkinson Disease
    Corpus Striatum
    Putamen
    Gray Matter
    Tyrosine 3-Monooxygenase
    Gait
    Freezing
    Parkinson Disease
    Catecholamines
    2015
    6 Citations (Scopus)

    A data mining methodology for predicting early stage Parkinson's disease using non-invasive, high-dimensional gait sensor data

    Tucker, C. S., Han, Y., Black Nembhard, H., Lee, W., Lewis, M., Sterling, N. & Huang, X., Oct 2 2015, In : IIE Transactions on Healthcare Systems Engineering. 5, 4, p. 238-254 17 p.

    Research output: Contribution to journalArticle

    Data Mining
    Gait
    Parkinson Disease
    Data mining
    Disease
    9 Citations (Scopus)

    Dopaminergic modulation of arm swing during gait among Parkinson's disease patients

    Sterling, N. W., Cusumano, J. P., Shaham, N., Piazza, S. J., Liu, G., Kong, L., Du, G., Lewis, M. & Huang, X., Jan 1 2015, In : Journal of Parkinson's Disease. 5, 1, p. 141-150 10 p.

    Research output: Contribution to journalArticle

    Gait
    Parkinson Disease
    Arm
    Dopamine Agents
    Forearm
    5 Citations (Scopus)

    Genome-wide meta-analysis on the sense of smell among US older adults

    Dong, J., Yang, J., Tranah, G., Franceschini, N., Parimi, N., Alkorta-Aranburu, G., Xu, Z., Alonso, A., Cummings, S. R., Fornage, M., Huang, X., Kritchevsky, S., Liu, Y., London, S., Niu, L., Wilson, R. S., De Jager, P. L., Yu, L., Singleton, A. B., Harris, T. & 4 others, Mosley, T. H., Pinto, J. M., Bennett, D. A. & Chen, H., Nov 1 2015, In : Medicine (United States). 94, 47, p. e1892

    Research output: Contribution to journalArticle

    Smell
    Meta-Analysis
    Genome
    Parkinson Disease
    Genome-Wide Association Study
    10 Citations (Scopus)

    Head injury, potential interaction with genes, and risk for Parkinson's disease

    Gao, J., Liu, R., Zhao, E., Huang, X., Nalls, M. A., Singleton, A. B. & Chen, H., Mar 1 2015, In : Parkinsonism and Related Disorders. 21, 3, p. 292-296 5 p.

    Research output: Contribution to journalArticle

    Craniocerebral Trauma
    Parkinson Disease
    Genes
    Confidence Intervals
    Genome-Wide Association Study
    33 Citations (Scopus)

    Heart rate variability and the risk of Parkinson disease: The Atherosclerosis Risk in Communities study

    Alonso, A., Huang, X., Mosley, T. H., Heiss, G. & Chen, H., May 1 2015, In : Annals of Neurology. 77, 5, p. 877-883 7 p.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Atherosclerosis
    Heart Rate
    Proportional Hazards Models
    Confidence Intervals
    17 Citations (Scopus)

    Machine learning classification of medication adherence in patients with movement disorders using non-wearable sensors

    Tucker, C. S., Behoora, I., Nembhard, H. B., Lewis, M., Sterling, N. W. & Huang, X., Nov 1 2015, In : Computers in Biology and Medicine. 66, p. 120-134 15 p.

    Research output: Contribution to journalArticle

    Medication Adherence
    Movement Disorders
    Learning systems
    Sensors
    Data mining
    40 Citations (Scopus)

    Meta-analyses on prevalence of selected Parkinson's nonmotor symptoms before and after diagnosis

    Chen, H., Zhao, E. J., Zhang, W., Lu, Y., Liu, R., Huang, X., Ciesielski-Jones, A. J., Justice, M. A., Cousins, D. S. & Peddada, S., Jan 8 2015, In : Translational Neurodegeneration. 4, 1, 1.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Meta-Analysis
    REM Sleep Behavior Disorder
    Constipation
    Publications
    35 Citations (Scopus)

    Potential sex differences in nonmotor symptoms in early drug-naive Parkinson disease

    Liu, R., Umbach, D. M., Peddada, S. D., Xu, Z., Tröster, A. I., Huang, X. & Chen, H., May 26 2015, In : Neurology. 84, 21, p. 2107-2115 9 p.

    Research output: Contribution to journalArticle

    Sex Characteristics
    Parkinson Disease
    Smell
    Pharmaceutical Preparations
    Area Under Curve
    11 Citations (Scopus)
    Parkinson Disease
    Parietal Lobe
    Brain
    Neurodegenerative Diseases
    Magnetic Resonance Spectroscopy
    57 Citations (Scopus)

    Statins, plasma cholesterol, and risk of Parkinson's disease: A prospective study

    Huang, X., Alonso, A., Guo, X., Umbach, D. M., Lichtenstein, M. L., Ballantyne, C. M., Mailman, R., Mosley, T. H. & Chen, H., Apr 1 2015, In : Movement Disorders. 30, 4, p. 552-559 8 p.

    Research output: Contribution to journalArticle

    Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Parkinson Disease
    Cholesterol
    Prospective Studies
    Lipids
    22 Citations (Scopus)

    T1 relaxation rate (R1) indicates nonlinear mn accumulation in brain tissue of welders with low-level exposure

    Lee, E. Y., Flynn, M. R., Du, G., Lewis, M., Fry, R., Herring, A. H., Van Buren, E., Van Buren, S., Smeester, L., Kong, L., Yang, Q., Mailman, R. & Huang, X., Aug 1 2015, In : Toxicological Sciences. 146, 2, p. 281-289 9 p.

    Research output: Contribution to journalArticle

    Manganese
    Brain
    Tissue
    Welding
    Globus Pallidus
    2014
    13 Citations (Scopus)

    Dietary fat intake and risk for Parkinson's disease

    Dong, J., Beard, J. D., Umbach, D. M., Park, Y., Huang, X., Blair, A., Kamel, F. & Chen, H., Nov 1 2014, In : Movement Disorders. 29, 13, p. 1623-1630 8 p.

    Research output: Contribution to journalArticle

    Dietary Fats
    Parkinson Disease
    Unsaturated Fatty Acids
    Fats
    Confidence Intervals
    22 Citations (Scopus)

    Dopaminergic modulation of motor coordinaton in Parkinson's disease

    Park, J., Lewis, M., Huang, X. & Latash, M., Jan 1 2014, In : Parkinsonism and Related Disorders. 20, 1, p. 64-68 5 p.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Fingers
    Pharmaceutical Preparations
    Social Adjustment
    Hand
    20 Citations (Scopus)

    Female reproductive factors, menopausal hormone use, and Parkinson's disease

    Liu, R., Baird, D., Park, Y., Freedman, N. D., Huang, X., Hollenbeck, A., Blair, A. & Chen, H., Jan 1 2014, In : Movement Disorders. 29, 7, p. 889-896 8 p.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Hormones
    Confidence Intervals
    Odds Ratio
    Menopause
    11 Citations (Scopus)

    History of smoking and olfaction in Parkinson's disease

    Lucassen, E., Sterling, N. W., Lee, E. Y., Chen, H., Lewis, M., Kong, L. & Huang, X., Jan 1 2014, In : Movement Disorders. 29, 8, p. 1069-1074 6 p.

    Research output: Contribution to journalArticle

    Smell
    Parkinson Disease
    Smoking
    Monoamine Oxidase Inhibitors
    Monoamine Oxidase
    11 Citations (Scopus)

    Individual and joint prevalence of three nonmotor symptoms of PD in the US general population

    Chen, H., Huang, X., Guo, X. & Peddada, S., Jan 1 2014, In : Movement Disorders. 29, 10, p. 1316-1319 4 p.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Joints
    Population
    Nutrition Surveys
    13 Citations (Scopus)

    Microstructural changes in the substantia nigra of asymptomatic agricultural workers

    Du, G., Lewis, M., Sterling, N. W., Kong, L., Chen, H., Mailman, R. & Huang, X., Jan 1 2014, In : Neurotoxicology and Teratology. 41, p. 60-64 5 p.

    Research output: Contribution to journalArticle

    Substantia Nigra
    Pesticides
    Parkinson Disease
    Anisotropy
    Magnetic resonance
    39 Citations (Scopus)

    Multi-atlas segmentation of subcortical brain structures via the AutoSeg software pipeline

    Wang, J., Vachet, C., Rumple, A., Gouttard, S., Ouziel, C., Perrot, E., Du, G., Huang, X., Gerig, G. & Styner, M., Feb 6 2014, In : Frontiers in Neuroinformatics. 8, FEB, 7.

    Research output: Contribution to journalArticle

    Atlases
    Brain
    Software
    Pipelines
    Tissue
    23 Citations (Scopus)

    Olfactory-related cortical atrophy is associated with olfactory dysfunction in Parkinson's disease

    Lee, E. Y., Eslinger, P., Du, G., Kong, L., Lewis, M. & Huang, X., Jan 1 2014, In : Movement Disorders. 29, 9, p. 1205-1208 4 p.

    Research output: Contribution to journalArticle

    Atrophy
    Parkinson Disease
    Prefrontal Cortex
    Brain
    Smell
    23 Citations (Scopus)

    Prehension synergies and hand function in early-stage Parkinson’s disease

    Jo, H. J., Park, J., Lewis, M., Huang, X. & Latash, M., Jan 1 2014, In : Experimental Brain Research. 233, 2, p. 425-440 16 p.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Hand
    Glass
    Hand Strength
    Water
    21 Citations (Scopus)

    Susceptibility loci for pigmentation and melanoma in relation to Parkinson's disease

    Dong, J., Gao, J., Nalls, M., Gao, X., Huang, X., Han, J., Singleton, A. B. & Chen, H., Jan 1 2014, In : Neurobiology of Aging. 35, 6, p. 1512.e5-1512.e10

    Research output: Contribution to journalArticle

    Pigmentation
    Parkinson Disease
    Melanoma
    Single Nucleotide Polymorphism
    Genome-Wide Association Study
    10 Citations (Scopus)

    The perplexing paradox of paraquat: The case for host-based susceptibility and postulated neurodegenerative effects

    Jones, B. C., Huang, X., Mailman, R., Lu, L. & Williams, R. W., Jan 1 2014, In : Journal of Biochemical and Molecular Toxicology. 28, 5, p. 191-197 7 p.

    Research output: Contribution to journalArticle

    Paraquat
    Gene-Environment Interaction
    Herbicides
    Biomarkers
    Agriculture
    2013
    19 Citations (Scopus)

    Alcohol Consumption, Types of Alcohol, and Parkinson's Disease

    Liu, R., Guo, X., Park, Y., Wang, J., Huang, X., Hollenbeck, A., Blair, A. & Chen, H., Jun 19 2013, In : PloS one. 8, 6, e66452.

    Research output: Contribution to journalArticle

    Parkinson disease
    Alcohol Drinking
    Parkinson Disease
    alcohols
    Alcohols
    35 Citations (Scopus)

    Early cortical gray matter loss and cognitive correlates in non-demented Parkinson's patients

    Lee, E. Y., Sen, S., Eslinger, P., Wagner, D., Shaffer, M. L., Kong, L., Lewis, M., Du, G. & Huang, X., Dec 1 2013, In : Parkinsonism and Related Disorders. 19, 12, p. 1088-1093 6 p.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Occipital Lobe
    Frontal Lobe
    Gray Matter
    Corpus Striatum
    34 Citations (Scopus)

    Effects of olivo-ponto-cerebellar atrophy (OPCA) on finger interaction and coordination

    Park, J., Lewis, M., Huang, X. & Latash, M., May 1 2013, In : Clinical Neurophysiology. 124, 5, p. 991-998 8 p.

    Research output: Contribution to journalArticle

    Olivopontocerebellar Atrophies
    Fingers
    Advisory Committees
    Ataxia
    Cerebellum
    21 Citations (Scopus)

    Effects of Parkinson's disease on optimization and structure of variance in multi-finger tasks

    Park, J., Jo, H. J., Lewis, M., Huang, X. & Latash, M., Nov 1 2013, In : Experimental Brain Research. 231, 1, p. 51-63 13 p.

    Research output: Contribution to journalArticle

    Fingers
    Parkinson Disease
    Basal Ganglia
    Control Groups
    27 Citations (Scopus)

    Higher iron in the red nucleus marks Parkinson's dyskinesia

    Lewis, M., Du, G., Kidacki, M., Patel, N., Shaffer, M. L., Mailman, R. & Huang, X., May 1 2013, In : Neurobiology of Aging. 34, 5, p. 1497-1503 7 p.

    Research output: Contribution to journalArticle

    Red Nucleus
    Dyskinesias
    Parkinson Disease
    Iron
    Levodopa
    8 Citations (Scopus)

    Short communication: Genetic variations of SLC2A9 in relation to Parkinson's disease

    Gao, J., Xu, H., Huang, X. & Chen, H., Feb 19 2013, In : Translational Neurodegeneration. 2, 1, 5.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Communication
    Single Nucleotide Polymorphism
    Odds Ratio
    Uric Acid
    37 Citations (Scopus)

    Striatal shape in Parkinson's disease

    Sterling, N. W., Du, G., Lewis, M., Dimaio, C., Kong, L., Eslinger, P., Styner, M. & Huang, X., Nov 1 2013, In : Neurobiology of Aging. 34, 11, p. 2510-2516 7 p.

    Research output: Contribution to journalArticle

    Corpus Striatum
    Putamen
    Parkinson Disease
    Atrophy
    Head
    27 Citations (Scopus)

    The Val158Met COMT polymorphism is a modifier of the age at onset in Parkinson's disease with a sexual dimorphism

    Klebe, S., Golmard, J. L., Nalls, M. A., Saad, M., Singleton, A. B., Bras, J. M., Hardy, J., Simon-Sanchez, J., Heutink, P., Kuhlenbäumer, G., Charfi, R., Klein, C., Hagenah, J., Gasser, T., Wurster, I., Lesage, S., Lorenz, D., Deuschl, G., Durif, F., Pollak, P. & 157 others, Damier, P., Tison, F., Durr, A., Amouyel, P., Lambert, J. C., Tzourio, C., Maubaret, C., Charbonnier-Beaupel, F., Tahiri, K., Vidailhet, M., Martinez, M., Brice, A., Corvol, J. C., Agid, Y., Anheim, M., Bonnet, A. M., Borg, M., Brice, A., Broussolle, E., Corvol, J. C., Damier, P., Destée, A., Durif, F., Klebe, S., Lohmann, E., Martinez, M., Penet, C., Pollak, P., Krack, P., Rascol, O., Tison, F., Tranchant, C., Vérin, M., Viallet, F., Vidailhet, M., Nalls, M. A., Plagnol, V., Bras, J. M., Hernandez, D. G., Sharma, M., Sheerin, U. M., Schulte, C., Sveinbjörnsdóttir, S., Arepalli, S., Band, G., Vukcevic, D., Barker, R. A., Bellinguez, C., Ben-Shlomo, Y., Berendse, H. W., Berg, D., Bhatia, K., De Bie, R. M. A., Biffi, A., Bloem, B., Bochdanovits, Z., Bonin, M., Brockmann, K., Brooks, J., Burn, D. J., Charlesworth, G., Chen, H., Chinnery, P. F., Chong, S., Clarke, C. E., Cookson, M. R., Cooper, J. M., Corvol, J. C., Counsell, C., Dartigues, J. F., Deloukas, P., Dexter, D. T., Van Dijk, K. D., Dillman, A., Durif, F., Edkins, S., Evans, J. R., Foltynie, T., Freeman, C., Gao, J., Gardner, M., Gibbs, R., Goate, A., Gray, E., Guerreiro, R., Gústafsson, Ó., Harris, C., Hellenthal, G., Van Hilten, J. J., Hofman, A., Hollenbeck, A., Holton, J., Hu, M., Huang, X., Huber, H., Hudson, G., Hunt, S. E., Huttenlocher, J., Illig, T., Jónsson, P. V., Langford, C., Lees, A., Lichtner, P., Limousin, P., Lopez, G., McNeill, A., Moorby, C., Moore, M., Morris, H., Morrison, K. E., Mudanohwo, E., O'Sullivan, S. S., Pearson, J., Pearson, R., Perlmutter, J. S., Pétursson, H., Pirinen, M., Post, B., Ravina, B., Revesz, T., Riess, O., Rivadeneira, F., Rizzu, P., Ryten, M., Sawcer, S., Schapira, A., Scheffer, H., Shaw, K., Shoulson, I., Sidransky, E., De Silva, R., Smith, C., Spencer, C. C. A., Stefánsson, H., Steinberg, S., Stockton, J. D., Strange, A., Su, Z., Talbot, K., Tanner, C. M., Tashakkori-Ghanbaria, A., Trabzuni, D., Traynor, B. J., Uitterlinden, A. G., Vandrovcova, J., Velseboer, D., Marie Vidailhet, V., Walker, R., Van De Warrenburg, B., Weale, M. E., Wickremaratchi, M., Williams, N., Williams-Gray, C. H., Winder-Rhodes, S., Stefánsson, K., Wood, N. W. & Singleton, A. B., Jun 1 2013, In : Journal of Neurology, Neurosurgery and Psychiatry. 84, 6, p. 666-673 8 p.

    Research output: Contribution to journalArticle

    Sex Characteristics
    Age of Onset
    Parkinson Disease
    Genotype
    Multivariate Analysis
    2012
    19 Citations (Scopus)

    An exploratory analysis on gene-environment interactions for Parkinson disease

    Gao, J., Nalls, M. A., Shi, M., Joubert, B. R., Hernandez, D. G., Huang, X., Hollenbeck, A., Singleton, A. B. & Chen, H., Jan 1 2012, In : Neurobiology of Aging. 33, 10, p. 2528.e1-2528.e6

    Research output: Contribution to journalArticle

    Gene-Environment Interaction
    Parkinson Disease
    Caffeine
    Single Nucleotide Polymorphism
    Smoking

    An exploratory analysis on gene-environment interactions for Parkinson disease.

    Gao, J., Nalls, M. A., Shi, M., Joubert, B. R., Hernandez, D. G., Huang, X., Hollenbeck, A., Singleton, A. B. & Chen, H., Oct 1 2012, In : Neurobiology of Aging. 33, 10

    Research output: Contribution to journalArticle

    Gene-Environment Interaction
    Parkinson Disease
    Caffeine
    Single Nucleotide Polymorphism
    Smoking
    51 Citations (Scopus)

    Both coordination and symmetry of arm swing are reduced in Parkinson's disease

    Huang, X., Mahoney, J. M., Lewis, M. M., Guangwei Du, D., Piazza, S. J. & Cusumano, J. P., Mar 1 2012, In : Gait and Posture. 35, 3, p. 373-377 5 p.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Arm
    Gait
    Tremor
    Forearm
    74 Citations (Scopus)

    Caffeine intake, smoking, and risk of parkinson disease in men and women

    Liu, R., Guo, X., Park, Y., Huang, X., Sinha, R., Freedman, N. D., Hollenbeck, A. R., Blair, A. & Chen, H., Jun 1 2012, In : American journal of epidemiology. 175, 11, p. 1200-1207 8 p.

    Research output: Contribution to journalArticle

    Caffeine
    Parkinson Disease
    Smoking
    Confidence Intervals
    Logistic Models
    71 Citations (Scopus)

    Changes in multifinger interaction and coordination in Parkinson's disease

    Park, J., Wu, Y. H., Lewis, M., Huang, X. & Latash, M., Aug 1 2012, In : Journal of neurophysiology. 108, 3, p. 915-924 10 p.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Fingers
    Social Adjustment
    Hand
    Advisory Committees
    68 Citations (Scopus)

    Imaging nigral pathology and clinical progression in Parkinson's disease

    Du, G., Lewis, M., Sen, S., Wang, J., Shaffer, M. L., Styner, M., Yang, Q. & Huang, X., Nov 1 2012, In : Movement Disorders. 27, 13, p. 1636-1643 8 p.

    Research output: Contribution to journalArticle

    Clinical Pathology
    Substantia Nigra
    Parkinson Disease
    Anisotropy
    Diffusion Tensor Imaging
    9 Citations (Scopus)

    Serum cholesterol and nigrostriatal R2* values in Parkinson's disease

    Du, G., Lewis, M., Shaffer, M. L., Chen, H., Yang, Q., Mailman, R. & Huang, X., Apr 17 2012, In : PloS one. 7, 4, e35397.

    Research output: Contribution to journalArticle

    Parkinson disease
    Parkinson Disease
    Cholesterol
    cholesterol
    Iron
    96 Citations (Scopus)

    Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease

    Keller, M. F., Saad, M., Bras, J., Bettella, F., Nicolaou, N., Simón-Sánchez, J., Mittag, F., Büchel, F., Sharma, M., Gibbs, J. R., Schulte, C., Moskvina, V., Durr, A., Holmans, P., Kilarski, L. L., Guerreiro, R., Hernandez, D. G., Brice, A., Ylikotila, P., Stefánsson, H. & 159 others, Majamaa, K., Morris, H. R., Williams, N., Gasser, T., Heutink, P., Wood, N. W., Hardy, J., Martinez, M., Singleton, A. B., Nalls, M. A., Plagnol, V., Sheerin, U. M., Lesage, S., Sveinbjörnsdóttir, S., Arepalli, S., Barker, R., Ben-Shlomo, Y., Berendse, H. W., Berg, D., Bhatia, K., de Bie, R. M. A., Biffi, A., Bloem, B., Bochdanovits, Z., Bonin, M., Brockmann, K., Brooks, J., Burn, D. J., Charlesworth, G., Chen, H., Chinnery, P. F., Chong, S., Clarke, C. E., Cookson, M. R., Cooper, J. M., Corvol, J. C., Counsell, C., Damier, P., Dartigues, J. F., Deloukas, P., Deuschl, G., Dexter, D. T., van Dijk, K. D., Dillman, A., Durif, F., Dürr, A., Edkins, S., Evans, J. R., Foltynie, T., Gao, J., Gardner, M., Goate, A., Gray, E., Gústafsson, Ó., Harris, C., van Hilten, J. J., Hofman, A., Hollenbeck, A., Holton, J., Hu, M., Huang, X., Huber, H., Hudson, G., Hunt, S. E., Huttenlocher, J., Illig, T., Jónsson, P. V., Lambert, J. C., Langford, C., Lees, A., Lichtner, P., Limousin, P., Lopez, G., Lorenz, D., McNeill, A., Moorby, C., Moore, M., Morrison, K. E., Mudanohwo, E., O'Sullivan, S. S., Pearson, J., Perlmutter, J. S., Pétursson, H., Pollak, P., Post, B., Potter, S. C., Ravina, B., Revesz, T., Riess, O., Rivadeneira, F., Rizzu, P., Ryten, M., Sawcer, S. J., Schapira, A., Scheffer, H., Shaw, K., Shoulson, I., Sidransky, E., Smith, C., Spencer, C. C. A., Steinberg, S., Stockton, J. D., Strange, A., Talbot, K., Tanner, C. M., Tashakkori-Ghanbaria, A., Tison, F., Trabzuni, D., Traynor, B. J., Uitterlinden, A. G., Velseboer, D., Vidailhet, M., Walker, R., van de Warrenburg, B., Wickremaratchi, M., Williams-Gray, C. H., Winder-Rhodes, S., Stefánsson, K., Donnelly, P., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Duncanson, A., Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Plomin, R., Rautanen, A., Trembath, R. C., Viswanathan, A. C., Band, G., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Pirinen, M., Pearson, R., Su, Z., Vukcevic, D., Gwilliam, R., Blackburn, H., Bumpstead, S. J., Dronov, S., Gillman, M., Hammond, N., Jayakumar, A., McCann, O. T., Liddle, J., Ravindrarajah, R., Ricketts, M., Waller, M., Weston, P., Widaa, S., Whittaker, P. & McCarthy, M. I., Jan 1 2012, In : Human Molecular Genetics. 21, 22, p. 4996-5009 14 p.

    Research output: Contribution to journalArticle

    Genome-Wide Association Study
    Parkinson Disease
    Genome
    Single Nucleotide Polymorphism
    Linear Models
    2011
    24 Citations (Scopus)

    An exploratory study on CLU, CR1 and PICALM and Parkinson disease

    Gao, J., Huang, X., Park, Y. Y., Hollenbeck, A. & Chen, H., Sep 6 2011, In : PLoS One. 6, 8, e24211.

    Research output: Contribution to journalArticle

    Parkinson disease
    Parkinson Disease
    odds ratio
    dementia
    confidence interval
    6 Citations (Scopus)

    An exploratory study on the CHRNA3-CHRNA5-CHRNB4 cluster, smoking, and Parkinson's disease

    Gao, J., Xu, H., Weinberg, C., Huang, X., Park, Y., Hollenbeck, A., Blair, A., Schatzkin, A., Burch, L. & Chen, H., Jun 1 2011, In : Neurodegenerative Diseases. 8, 5, p. 296-299 4 p.

    Research output: Contribution to journalArticle

    Parkinson Disease
    Single Nucleotide Polymorphism
    Smoking
    Genome-Wide Association Study
    Tobacco Use Disorder
    25 Citations (Scopus)

    Apolipoprotein E genotypes and the risk of Parkinson disease

    Gao, J., Huang, X., Park, Y., Liu, R., Hollenbeck, A., Schatzkin, A., Mailman, R. & Chen, H., Jan 1 2011, In : Neurobiology of Aging. 32, 11, p. 2106.e1-2106.e6

    Research output: Contribution to journalArticle

    Apolipoproteins E
    Parkinson Disease
    Odds Ratio
    Genotype
    Confidence Intervals
    109 Citations (Scopus)

    Combined R2* and Diffusion Tensor Imaging Changes in the Substantia Nigra in Parkinson's Disease

    Du, G., Lewis, M., Styner, M., Shaffer, M. L., Sen, S., Yang, Q. & Huang, X., Aug 1 2011, In : Movement Disorders. 26, 9, p. 1627-1632 6 p.

    Research output: Contribution to journalArticle

    Diffusion Tensor Imaging
    Anisotropy
    Substantia Nigra
    Parkinson Disease
    Magnetic Resonance Imaging