Yan Zhuang, MD

    • 1378 Citations
    • 14 h-Index
    20032018
    If you made any changes in Pure, your changes will be visible here soon.

    Fingerprint Dive into the research topics where Yan Zhuang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

    • 2 Similar Profiles
    Neoplasms Medicine & Life Sciences
    P-Glycoprotein Medicine & Life Sciences
    Lipoylation Medicine & Life Sciences
    Cyclin-Dependent Kinase 9 Medicine & Life Sciences
    Ceramidases Medicine & Life Sciences
    Multiple Drug Resistance Medicine & Life Sciences
    Ceramides Medicine & Life Sciences
    Acyltransferases Medicine & Life Sciences

    Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Research Output 2003 2018

    • 1378 Citations
    • 14 h-Index
    • 15 Article
    1 Citation (Scopus)

    In vitro and in vivo antitumor and anti-inflammatory capabilities of the novel GSK3 and CDK9 inhibitor ABC1183s

    Schrecengost, R. S., Green, C. L., Zhuang, Y., Keller, S. N., Smith, R. A., Maines, L. W. & Smith, C., Apr 1 2018, In : Journal of Pharmacology and Experimental Therapeutics. 365, 1, p. 107-116 10 p.

    Research output: Contribution to journalArticle

    Cyclin-Dependent Kinase 9
    Anti-Inflammatory Agents
    Inflammation
    Peptide Elongation Factors
    Glycogen Synthase Kinases
    27 Citations (Scopus)

    A phase I study of ABC294640, a first-in-class sphingosine kinase-2 inhibitor, in patients with advanced solid tumors

    Britten, C. D., Garrett-Mayer, E., Chin, S. H., Shirai, K., Ogretmen, B., Bentz, T. A., Brisendine, A., Anderton, K., Cusack, S. L., Maines, L. W., Zhuang, Y., Smith, C. & Thomas, M. B., Aug 15 2017, In : Clinical Cancer Research. 23, 16, p. 4642-4650 9 p.

    Research output: Contribution to journalArticle

    Neoplasms
    Sphingolipids
    Drug-Related Side Effects and Adverse Reactions
    Nausea
    Vomiting
    28 Citations (Scopus)

    Attenuation of arthritis in rodents by a novel orally-available inhibitor of sphingosine kinase

    Fitzpatrick, L. R., Green, C., Frauenhoffer, E., French, K. J., Zhuang, Y., Maines, L. W., Upson, J. J., Paul, E., Donahue, H., Mosher, T. & Smith, C., Apr 1 2011, In : Inflammopharmacology. 19, 2, p. 75-87 13 p.

    Research output: Contribution to journalArticle

    Experimental Arthritis
    Arthritis
    Rodentia
    Methotrexate
    Indomethacin
    43 Citations (Scopus)

    Combined anticancer effects of sphingosine kinase inhibitors and sorafenib

    Beljanski, V., Knaak, C., Zhuang, Y. & Smith, C., Dec 1 2011, In : Investigational New Drugs. 29, 6, p. 1132-1142 11 p.

    Research output: Contribution to journalArticle

    Growth
    Neoplasms
    Adenocarcinoma
    Caspase 7
    Lipids
    32 Citations (Scopus)

    Discovery and evaluation of inhibitors of human ceramidase

    Draper, J. M., Xia, Z., Smith, R. A., Zhuang, Y., Wang, W. & Smith, C., Nov 1 2011, In : Molecular cancer therapeutics. 10, 11, p. 2052-2061 10 p.

    Research output: Contribution to journalArticle

    Ceramidases
    Ceramides
    Sphingosine
    Small Molecule Libraries
    Neoplasms