Yan Zhuang, MD

    • 1391 Citations
    • 14 h-Index
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    Fingerprint Dive into the research topics where Yan Zhuang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

    • 2 Similar Profiles
    Neoplasms Medicine & Life Sciences
    P-Glycoprotein Medicine & Life Sciences
    Lipoylation Medicine & Life Sciences
    Cyclin-Dependent Kinase 9 Medicine & Life Sciences
    Ceramidases Medicine & Life Sciences
    Multiple Drug Resistance Medicine & Life Sciences
    Ceramides Medicine & Life Sciences
    Acyltransferases Medicine & Life Sciences

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    Research Output 2003 2018

    • 1391 Citations
    • 14 h-Index
    • 15 Article
    1 Citation (Scopus)

    In vitro and in vivo antitumor and anti-inflammatory capabilities of the novel GSK3 and CDK9 inhibitor ABC1183s

    Schrecengost, R. S., Green, C. L., Zhuang, Y., Keller, S. N., Smith, R. A., Maines, L. W. & Smith, C., Apr 1 2018, In : Journal of Pharmacology and Experimental Therapeutics. 365, 1, p. 107-116 10 p.

    Research output: Contribution to journalArticle

    Cyclin-Dependent Kinase 9
    Anti-Inflammatory Agents
    Peptide Elongation Factors
    Glycogen Synthase Kinases
    29 Citations (Scopus)

    A phase I study of ABC294640, a first-in-class sphingosine kinase-2 inhibitor, in patients with advanced solid tumors

    Britten, C. D., Garrett-Mayer, E., Chin, S. H., Shirai, K., Ogretmen, B., Bentz, T. A., Brisendine, A., Anderton, K., Cusack, S. L., Maines, L. W., Zhuang, Y., Smith, C. D. & Thomas, M. B., Aug 15 2017, In : Clinical Cancer Research. 23, 16, p. 4642-4650 9 p.

    Research output: Contribution to journalArticle

    Drug-Related Side Effects and Adverse Reactions
    28 Citations (Scopus)

    Attenuation of arthritis in rodents by a novel orally-available inhibitor of sphingosine kinase

    Fitzpatrick, L. R., Green, C., Frauenhoffer, E., French, K. J., Zhuang, Y., Maines, L. W., Upson, J. J., Paul, E., Donahue, H., Mosher, T. & Smith, C., Apr 1 2011, In : Inflammopharmacology. 19, 2, p. 75-87 13 p.

    Research output: Contribution to journalArticle

    Experimental Arthritis
    43 Citations (Scopus)

    Combined anticancer effects of sphingosine kinase inhibitors and sorafenib

    Beljanski, V., Knaak, C., Zhuang, Y. & Smith, C., Dec 1 2011, In : Investigational New Drugs. 29, 6, p. 1132-1142 11 p.

    Research output: Contribution to journalArticle

    Caspase 7
    32 Citations (Scopus)

    Discovery and evaluation of inhibitors of human ceramidase

    Draper, J. M., Xia, Z., Smith, R. A., Zhuang, Y., Wang, W. & Smith, C. D., Nov 1 2011, In : Molecular cancer therapeutics. 10, 11, p. 2052-2061 10 p.

    Research output: Contribution to journalArticle

    Small Molecule Libraries