Projects per year
Personal profile
Research interests
Dr. Yang Yang's research interest is to understand neural mechanism of cognition via tools of behavior, electrophysiology and pharmacology. Diseases of interest include neurological and neurodegenerative disorders and addiction. Key disciplines include neuroscience, electrophysiology, behavior and addiction, physiology, pharmacology, drug development and discovery and translational medicine.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Biophysics, PhD, Chinese Academy of Sciences
… → 2008
Biomedical Engineering, BA, Capital Medical University
… → 2003
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Discovery of functionally selective dopamine ligands for age-related cognitive decline
Yang, Y., Mailman, R. & Dokholyan, N.
6/1/21 → 5/31/24
Project: Research project
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Dopamine D1-KCNQ Channel Influences on Dorsolateral Prefrontal Cortical Network Physiology in Primates
Brain and Behavior Research Foundation
1/1/13 → 1/1/16
Project: Research project
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Nicotinic Restoration of Prefrontal Cortex Physiology in Aged Monkeys
American Federation for Aging Research
1/1/10 → 6/30/11
Project: Research project
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A Dopamine D1 Agonist Versus Methylphenidate in Modulating Prefrontal Cortical Working Memory
Yang, Y., Lewis, M. M., Kong, L. & Mailman, R. B., Aug 1 2022, In: Journal of Pharmacology and Experimental Therapeutics. 382, 2, p. 88-99 12 p.Research output: Contribution to journal › Article › peer-review
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Dopamine D1 receptor-mediated β-arrestin signaling: Insight from pharmacology, biology, behavior, and neurophysiology
Yang, Y., Lewis, M. M., Huang, X., Dokholyan, N. V. & Mailman, R. B., Jul 2022, In: International Journal of Biochemistry and Cell Biology. 148, 106235.Research output: Contribution to journal › Short survey › peer-review
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Dose-Dependent Regulation on Prefrontal Neuronal Working Memory by Dopamine D1 Agonists: Evidence of Receptor Functional Selectivity-Related Mechanisms
Yang, Y., Kocher, S. D., Lewis, M. & Mailman, R. B., Jun 16 2022, In: Frontiers in Neuroscience. 16, 898051.Research output: Contribution to journal › Article › peer-review
Open Access -
D1, not D2, dopamine receptor activation dramatically improves MPTP-induced parkinsonism unresponsive to levodopa
Mailman, R. B., Yang, Y. & Huang, X., Feb 5 2021, In: European Journal of Pharmacology. 892, 173760.Research output: Contribution to journal › Article › peer-review
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D1 dopamine receptors intrinsic activity and functional selectivity affect working memory in prefrontal cortex
Yang, Y., Lee, S. M., Imamura, F., Gowda, K., Amin, S. & Mailman, R. B., Feb 2021, In: Molecular Psychiatry. 26, 2, p. 645-655 11 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations