• 2125 Citations
  • 22 h-Index
20002023

Research output per year

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Research Output

2019

Aptamer-Functionalized Fibrin Hydrogel Improves Vascular Endothelial Growth Factor Release Kinetics and Enhances Angiogenesis and Osteogenesis in Critically Sized Cranial Defects

Juhl, O., Zhao, N., Merife, A. B., Cohen, D., Friedman, M., Zhang, Y., Schwartz, Z., Wang, Y. & Donahue, H., Nov 11 2019, In : ACS Biomaterials Science and Engineering. 5, 11, p. 6152-6160 9 p.

Research output: Contribution to journalArticle

Assembly of Bifunctional Aptamer-Fibrinogen Macromer for VEGF Delivery and Skin Wound Healing

Zhao, N., Coyne, J., Xu, M., Zhang, X., Suzuki, A., Shi, P., Lai, J., Fong, G. H., Xiong, N. & Wang, Y., Feb 12 2019, In : Chemistry of Materials. 31, 3, p. 1006-1015 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Dual aptamer-functionalized in situ injectable fibrin hydrogel for promotion of angiogenesis via co-delivery of growth factors

Zhao, N., Suzuki, A., Zhang, X. & Wang, Y., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Dual Aptamer-Functionalized in Situ Injectable Fibrin Hydrogel for Promotion of Angiogenesis via Codelivery of Vascular Endothelial Growth Factor and Platelet-Derived Growth Factor-BB

Zhao, N., Suzuki, A., Zhang, X., Shi, P., Abune, L., Coyne, J., Jia, H., Xiong, N., Zhang, G. & Wang, Y., May 22 2019, In : ACS Applied Materials and Interfaces. 11, 20, p. 18123-18132 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
4 Scopus citations

Programmed Degradation of Hydrogels with a Double-Locked Domain

Lai, J., Abune, L., Zhao, N. & Wang, Y., Feb 25 2019, In : Angewandte Chemie - International Edition. 58, 9, p. 2820-2825 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Polyvalent Display of Biomolecules on Live Cells

Shi, P., Zhao, N., Lai, J., Coyne, J., Gaddes, E. R. & Wang, Y., Jun 4 2018, In : Angewandte Chemie - International Edition. 57, 23, p. 6800-6804 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Programmable hydrogels

Wang, Y., Sep 2018, In : Biomaterials. 178, p. 663-680 18 p.

Research output: Contribution to journalArticle

9 Scopus citations
2017

Aptamer-Functionalized Hydrogel for Self-Programmed Protein Release via Sequential Photoreaction and Hybridization

Lai, J., Jiang, P., Gaddes, E. R., Zhao, N., Abune, L. & Wang, Y., Jul 25 2017, In : Chemistry of Materials. 29, 14, p. 5850-5857 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Development of a Dual-Functional Hydrogel Using RGD and Anti-VEGF Aptamer

Zhao, N., Battig, M. R., Xu, M., Wang, X., Xiong, N. & Wang, Y., Nov 2017, In : Macromolecular Bioscience. 17, 11, 1700201.

Research output: Contribution to journalArticle

9 Scopus citations

Displacement and hybridization reactions in aptamer-functionalized hydrogels for biomimetic protein release and signal transduction

Lai, J., Li, S., Shi, X., Coyne, J., Zhao, N., Dong, F., Mao, Y. & Wang, Y., Jan 1 2017, In : Chemical Science. 8, 11, p. 7306-7311 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Nanoparticle-Programmed Surface for Drug Release and Cell Regulation via Reversible Hybridization Reaction

Jiang, P., Li, S., Lai, J., Zheng, H., Lin, C., Shi, P. & Wang, Y., Feb 8 2017, In : ACS Applied Materials and Interfaces. 9, 5, p. 4467-4474 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Polymer Microneedle Mediated Local Aptamer Delivery for Blocking the Function of Vascular Endothelial Growth Factor

Coyne, J., Davis, B., Kauffman, D., Zhao, N. & Wang, Y., Dec 11 2017, In : ACS Biomaterials Science and Engineering. 3, 12, p. 3395-3403 9 p.

Research output: Contribution to journalArticle

5 Scopus citations
2016

Chimeric Aptamer-Gelatin Hydrogels as an Extracellular Matrix Mimic for Loading Cells and Growth Factors

Zhang, X., Battig, M. R., Chen, N., Gaddes, E. R., Duncan, K. L. & Wang, Y., Mar 14 2016, In : Biomacromolecules. 17, 3, p. 778-787 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

Molecularly Regulated Reversible DNA Polymerization

Chen, N., Shi, X. & Wang, Y., Jun 1 2016, In : Angewandte Chemie - International Edition. 55, 23, p. 6657-6661 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

The morphology of self-assembled lipid-based nanoparticles affects their uptake by cancer cells

Aresh, W., Liu, Y., Sine, J., Thayer, D., Puri, A., Huang, Y., Wang, Y. & Nieh, M. P., Oct 1 2016, In : Journal of Biomedical Nanotechnology. 12, 10, p. 1852-1863 12 p.

Research output: Contribution to journalArticle

11 Scopus citations
2015

A Drosera-bioinspired hydrogel for catching and killing cancer cells

Li, S., Chen, N., Gaddes, E. R., Zhang, X., Dong, C. & Wang, Y., Sep 23 2015, In : Scientific reports. 5, 14297.

Research output: Contribution to journalArticle

16 Scopus citations

Aptamer-Based Polyvalent Ligands for Regulated Cell Attachment on the Hydrogel Surface

Gaddes, E. R., Gydush, G., Li, S., Chen, N., Dong, C. & Wang, Y., Apr 13 2015, In : Biomacromolecules. 16, 4, p. 1382-1389 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Molecular encryption and reconfiguration for remodeling of dynamic hydrogels

Li, S., Gaddes, E. R., Chen, N. & Wang, Y., May 11 2015, In : Angewandte Chemie - International Edition. 54, 20, p. 5957-5961 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Perspectives: Interplay Between Melanoma Regulated Fibrin and Receptor Mediated Adhesion Under Shear Flow

Ozdemir, T., Gaddes, E., Wang, Y. & Dong, C., Jan 1 2015, In : Cellular and Molecular Bioengineering. 8, 1, p. 86-95 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Regulation of fibrin-mediated tumor cell adhesion to the endothelium using anti-thrombin aptamer

Gaddes, E. R., Lee, D., Gydush, G., Wang, Y. & Dong, C., Dec 1 2015, In : Experimental Cell Research. 339, 2, p. 417-426 10 p.

Research output: Contribution to journalArticle

4 Scopus citations
2014

Aptamer-functionalized superporous hydrogels for sequestration and release of growth factors regulated via molecular recognition

Battig, M. R., Huang, Y., Chen, N. & Wang, Y., Sep 2014, In : Biomaterials. 35, 27, p. 8040-8048 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

Bioinspired affinity DNA polymers on nanoparticles for drug sequestration and detoxification

Chen, N., Huang, Y. & Wang, Y., Jan 1 2014, In : Biomaterials. 35, 36, p. 9709-9718 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Nucleic Acid Aptamers for Biomaterials Development

Battig, M. R. & Wang, Y., Jan 2014, Natural and Synthetic Biomedical Polymers. Elsevier Inc., p. 287-299 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Polymerization of affinity ligands on a surface for enhanced ligand display and cell binding

Richards, E., Li, S., Chen, N., Battig, M. R. & Wang, Y., Dec 8 2014, In : Biomacromolecules. 15, 12, p. 4561-4569 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
2013

DNA gold nanoparticle nanocomposite films for chemiresistive vapor sensing

Fu, K., Li, S., Jiang, X., Wang, Y. & Willis, B. G., Nov 19 2013, In : Langmuir. 29, 46, p. 14335-14343 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Endonuclease-responsive aptamer-functionalized hydrogel coating for sequential catch and release of cancer cells

Li, S., Chen, N., Zhang, Z. & Wang, Y., Jan 1 2013, In : Biomaterials. 34, 2, p. 460-469 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

Microfluidic platform with hierarchical micro/nanostructures and SELEX nucleic acid aptamer coating for isolation of circulating tumor cells

Swaminathan, V. V., Gannavaram, S., Li, S., Hu, H., Yeom, J., Wang, Y. & Zhu, L., Dec 1 2013, 2013 13th IEEE International Conference on Nanotechnology, IEEE-NANO 2013. p. 370-373 4 p. 6720968. (Proceedings of the IEEE Conference on Nanotechnology).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Polynucleotide-functionalized gold nanoparticles as chemiresistive vapor sensing elements

Fu, K., Pedrick, W., Wang, H., Lamarche, A., Jiang, X., Willis, B. G., Li, S. & Wang, Y., Jan 1 2013, IEEE SENSORS 2013 - Proceedings. IEEE Computer Society, 6688518. (Proceedings of IEEE Sensors).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Programmable display of DNA-protein chimeras for controlling cell-hydrogel interactions via reversible intermolecular hybridization

Zhang, Z., Li, S., Chen, N., Yang, C. & Wang, Y., Apr 8 2013, In : Biomacromolecules. 14, 4, p. 1174-1180 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Programmable hydrogels for the controlled release of therapeutic nucleic acid aptamers via reversible DNA hybridization

Zhang, X., Battig, M. R. & Wang, Y., Oct 25 2013, In : Chemical Communications. 49, 83, p. 9600-9602 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Programmable imaging amplification via nanoparticle-initiated DNA polymerization

Chen, N., Li, S., Battig, M. R. & Wang, Y., Dec 9 2013, In : Small. 9, 23, p. 3944-3949 6 p.

Research output: Contribution to journalArticle

7 Scopus citations
2012

Cell adhesion on an artificial extracellular matrix using aptamer-functionalized PEG hydrogels

Chen, N., Zhang, Z., Soontornworajit, B., Zhou, J. & Wang, Y., Feb 1 2012, In : Biomaterials. 33, 5, p. 1353-1362 10 p.

Research output: Contribution to journalArticle

50 Scopus citations

Enhanced loading and controlled release of antibiotics using nucleic acids as an antibiotic-binding effector in hydrogels

Zhang, X., Soontornworajit, B., Zhang, Z., Chen, N. & Wang, Y., Jul 9 2012, In : Biomacromolecules. 13, 7, p. 2202-2210 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Programmable hydrogels for controlled cell catch and release using hybridized aptamers and complementary sequences

Zhang, Z., Chen, N., Li, S., Battig, M. R. & Wang, Y., Sep 26 2012, In : Journal of the American Chemical Society. 134, 38, p. 15716-15719 4 p.

Research output: Contribution to journalArticle

93 Scopus citations

Programmable release of multiple protein drugs from aptamer-functionalized hydrogels via nucleic acid hybridization

Battig, M. R., Soontornworajit, B. & Wang, Y., Aug 1 2012, In : Journal of the American Chemical Society. 134, 30, p. 12410-12413 4 p.

Research output: Contribution to journalArticle

81 Scopus citations
2011

Affinity hydrogels for controlled protein release using nucleic acid aptamers and complementary oligonucleotides

Soontornworajit, B., Zhou, J., Snipes, M. P., Battig, M. R. & Wang, Y., Oct 1 2011, In : Biomaterials. 32, 28, p. 6839-6849 11 p.

Research output: Contribution to journalArticle

38 Scopus citations

An aptamer-functionalized hydrogel for controlled protein release: A modeling study

Fan, T. H., Soontornworajit, B., Karzar-Jeddi, M., Zhang, X. & Wang, Y., Oct 7 2011, In : Soft Matter. 7, 19, p. 9326-9334 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Folate-functionalized unimolecular micelles based on a degradable amphiphilic dendrimer-like star polymer for cancer cell-targeted drug delivery

Cao, W., Zhou, J., Mann, A., Wang, Y. & Zhu, L., Jul 11 2011, In : Biomacromolecules. 12, 7, p. 2697-2707 11 p.

Research output: Contribution to journalArticle

70 Scopus citations

Nucleic acid aptamers for clinical diagnosis: Cell detection and molecular imaging

Soontornworajit, B. & Wang, Y., Feb 1 2011, In : Analytical and Bioanalytical Chemistry. 399, 4, p. 1591-1599 9 p.

Research output: Contribution to journalReview article

60 Scopus citations

Structural prediction and binding analysis of hybridized aptamers

Zhou, J., Soontornworajit, B., Snipes, M. P. & Wang, Y., Jan 1 2011, In : Journal of Molecular Recognition. 24, 1, p. 119-126 8 p.

Research output: Contribution to journalArticle

12 Scopus citations
2010

A hybrid particle-hydrogel composite for oligonucleotide-mediated pulsatile protein release

Soontornworajit, B., Zhou, J. & Wang, Y., Sep 7 2010, In : Soft Matter. 6, 17, p. 4255-4261 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Aptamer-based molecular recognition for biosensor development

Zhou, J., Battig, M. R. & Wang, Y., Nov 1 2010, In : Analytical and Bioanalytical Chemistry. 398, 6, p. 2471-2480 10 p.

Research output: Contribution to journalReview article

92 Scopus citations

Aptamer-functionalized in situ injectable hydrogel for controlled protein release

Soontornworajit, B., Zhou, J., Zhang, Z. & Wang, Y., Oct 11 2010, In : Biomacromolecules. 11, 10, p. 2724-2730 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

A temperature-responsive antibody-like nanostructure

Zhou, J., Soontornworajit, B. & Wang, Y., Aug 9 2010, In : Biomacromolecules. 11, 8, p. 2087-2093 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Hydrogel functionalization with DNA aptamers for sustained PDGF-BB release

Soontornworajit, B., Zhou, J., Shaw, M. T., Fan, T. H. & Wang, Y., Mar 19 2010, In : Chemical Communications. 46, 11, p. 1857-1859 3 p.

Research output: Contribution to journalArticle

76 Scopus citations

Synthesis and in vitro cancer cell targeting of folate-functionalized biodegradable amphiphilic dendrimer-like star polymers

Cao, W., Zhou, J., Wang, Y. & Zhu, L., Dec 13 2010, In : Biomacromolecules. 11, 12, p. 3680-3687 8 p.

Research output: Contribution to journalArticle

40 Scopus citations
2009

A hybrid DNA aptamer-dendrimer nanomaterial for targeted cell labeling

Zhou, J., Soontornworajit, B., Martin, J., Sullenger, B. A., Gilboa, E. & Wang, Y., Sep 9 2009, In : Macromolecular Bioscience. 9, 9, p. 831-835 5 p.

Research output: Contribution to journalArticle

30 Scopus citations

Development of a novel pretargeting system with bifunctional nucleic acid molecules

Zhou, J., Soontornworajit, B., Snipes, M. P. & Wang, Y., Aug 28 2009, In : Biochemical and Biophysical Research Communications. 386, 3, p. 521-525 5 p.

Research output: Contribution to journalArticle

10 Scopus citations
2 Scopus citations