• 2078 Citations
  • 21 h-Index
20002023
If you made any changes in Pure, your changes will be visible here soon.

Research Output 2000 2019

Filter
Article
2019

Aptamer-Functionalized Fibrin Hydrogel Improves Vascular Endothelial Growth Factor Release Kinetics and Enhances Angiogenesis and Osteogenesis in Critically Sized Cranial Defects

Juhl, O., Zhao, N., Merife, A. B., Cohen, D., Friedman, M., Zhang, Y., Schwartz, Z., Wang, Y. & Donahue, H., Nov 11 2019, In : ACS Biomaterials Science and Engineering. 5, 11, p. 6152-6160 9 p.

Research output: Contribution to journalArticle

Hydrogel
Fibrin
Hydrogels
Vascular Endothelial Growth Factor A
Defects
5 Citations (Scopus)

Assembly of Bifunctional Aptamer-Fibrinogen Macromer for VEGF Delivery and Skin Wound Healing

Zhao, N., Coyne, J., Xu, M., Zhang, X., Suzuki, A., Shi, P., Lai, J., Fong, G. H., Xiong, N. & Wang, Y., Feb 12 2019, In : Chemistry of Materials. 31, 3, p. 1006-1015 10 p.

Research output: Contribution to journalArticle

Hydrogels
Fibrinogen
Vascular Endothelial Growth Factor A
Skin
Molecular recognition
3 Citations (Scopus)

Dual Aptamer-Functionalized in Situ Injectable Fibrin Hydrogel for Promotion of Angiogenesis via Codelivery of Vascular Endothelial Growth Factor and Platelet-Derived Growth Factor-BB

Zhao, N., Suzuki, A., Zhang, X., Shi, P., Abune, L., Coyne, J., Jia, H., Xiong, N., Zhang, G. & Wang, Y., May 22 2019, In : ACS Applied Materials and Interfaces. 11, 20, p. 18123-18132 10 p.

Research output: Contribution to journalArticle

Hydrogels
Hydrogel
Platelets
Fibrin
Vascular Endothelial Growth Factor A
3 Citations (Scopus)
Hydrogels
Nucleic acids
Fibroblast Growth Factor 2
Fibroblasts
Nucleic Acids

Programmed Degradation of Hydrogels with a Double-Locked Domain

Lai, J., Abune, L., Zhao, N. & Wang, Y., Feb 25 2019, In : Angewandte Chemie - International Edition. 58, 9, p. 2820-2825 6 p.

Research output: Contribution to journalArticle

Hydrogels
Degradation
Acids
Irradiation
Strategic materials
2018
5 Citations (Scopus)

Polyvalent Display of Biomolecules on Live Cells

Shi, P., Zhao, N., Lai, J., Coyne, J., Gaddes, E. R. & Wang, Y., Jun 4 2018, In : Angewandte Chemie - International Edition. 57, 23, p. 6800-6804 5 p.

Research output: Contribution to journalArticle

Biomolecules
Display devices
8 Citations (Scopus)

Programmable hydrogels

Wang, Y., Sep 1 2018, In : Biomaterials. 178, p. 663-680 18 p.

Research output: Contribution to journalArticle

Hydrogels
Physical Stimulation
Chemical Stimulation
Biophysics
Cell Separation
2017
9 Citations (Scopus)

Aptamer-Functionalized Hydrogel for Self-Programmed Protein Release via Sequential Photoreaction and Hybridization

Lai, J., Jiang, P., Gaddes, E. R., Zhao, N., Abune, L. & Wang, Y., Jul 25 2017, In : Chemistry of Materials. 29, 14, p. 5850-5857 8 p.

Research output: Contribution to journalArticle

Hydrogel
Hydrogels
Proteins
8 Citations (Scopus)

Development of a Dual-Functional Hydrogel Using RGD and Anti-VEGF Aptamer

Zhao, N., Battig, M. R., Xu, M., Wang, X., Xiong, N. & Wang, Y., Nov 2017, In : Macromolecular Bioscience. 17, 11, 1700201.

Research output: Contribution to journalArticle

Hydrogel
Biocompatible Materials
Biomaterials
Hydrogels
Vascular Endothelial Growth Factor A
5 Citations (Scopus)

Displacement and hybridization reactions in aptamer-functionalized hydrogels for biomimetic protein release and signal transduction

Lai, J., Li, S., Shi, X., Coyne, J., Zhao, N., Dong, F., Mao, Y. & Wang, Y., Jan 1 2017, In : Chemical Science. 8, 11, p. 7306-7311 6 p.

Research output: Contribution to journalArticle

Signal transduction
Hydrogels
Biomimetics
Molecules
Hydrogel
2 Citations (Scopus)

Nanoparticle-Programmed Surface for Drug Release and Cell Regulation via Reversible Hybridization Reaction

Jiang, P., Li, S., Lai, J., Zheng, H., Lin, C., Shi, P. & Wang, Y., Feb 8 2017, In : ACS Applied Materials and Interfaces. 9, 5, p. 4467-4474 8 p.

Research output: Contribution to journalArticle

Nanoparticles
Pharmaceutical Preparations
Stents
Oligonucleotides
Drug delivery
5 Citations (Scopus)

Polymer Microneedle Mediated Local Aptamer Delivery for Blocking the Function of Vascular Endothelial Growth Factor

Coyne, J., Davis, B., Kauffman, D., Zhao, N. & Wang, Y., Dec 11 2017, In : ACS Biomaterials Science and Engineering. 3, 12, p. 3395-3403 9 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Polymers
Proteins
Nucleotide Aptamers
Nucleic acids
2016
19 Citations (Scopus)

Chimeric Aptamer-Gelatin Hydrogels as an Extracellular Matrix Mimic for Loading Cells and Growth Factors

Zhang, X., Battig, M. R., Chen, N., Gaddes, E. R., Duncan, K. L. & Wang, Y., Mar 14 2016, In : Biomacromolecules. 17, 3, p. 778-787 10 p.

Research output: Contribution to journalArticle

Hydrogels
Hydrogel
Gelatin
Intercellular Signaling Peptides and Proteins
Bioactivity
4 Citations (Scopus)

Molecularly Regulated Reversible DNA Polymerization

Chen, N., Shi, X. & Wang, Y., Jun 1 2016, In : Angewandte Chemie - International Edition. 55, 23, p. 6657-6661 5 p.

Research output: Contribution to journalArticle

Polymers
DNA
Polymerization
Natural polymers
Nucleic acids
11 Citations (Scopus)

The morphology of self-assembled lipid-based nanoparticles affects their uptake by cancer cells

Aresh, W., Liu, Y., Sine, J., Thayer, D., Puri, A., Huang, Y., Wang, Y. & Nieh, M. P., Oct 1 2016, In : Journal of Biomedical Nanotechnology. 12, 10, p. 1852-1863 12 p.

Research output: Contribution to journalArticle

Nanoparticles
Lipids
Cells
Small Angle Scattering
Caveolae
2015
15 Citations (Scopus)

A Drosera-bioinspired hydrogel for catching and killing cancer cells

Li, S., Chen, N., Gaddes, E. R., Zhang, X., Dong, C. & Wang, Y., Sep 23 2015, In : Scientific reports. 5, 14297.

Research output: Contribution to journalArticle

Drosera
Hydrogel
Neoplasms
Doxorubicin
Circulating Neoplastic Cells
15 Citations (Scopus)

Aptamer-Based Polyvalent Ligands for Regulated Cell Attachment on the Hydrogel Surface

Gaddes, E. R., Gydush, G., Li, S., Chen, N., Dong, C. & Wang, Y., Apr 13 2015, In : Biomacromolecules. 16, 4, p. 1382-1389 8 p.

Research output: Contribution to journalArticle

Hydrogel
Hydrogels
Ligands
Biomolecules
Shear stress
13 Citations (Scopus)

Molecular encryption and reconfiguration for remodeling of dynamic hydrogels

Li, S., Gaddes, E. R., Chen, N. & Wang, Y., May 11 2015, In : Angewandte Chemie - International Edition. 54, 20, p. 5957-5961 5 p.

Research output: Contribution to journalArticle

Hydrogels
Cryptography
Ligands
Cell adhesion
Hydrogel
2 Citations (Scopus)

Perspectives: Interplay Between Melanoma Regulated Fibrin and Receptor Mediated Adhesion Under Shear Flow

Ozdemir, T., Gaddes, E., Wang, Y. & Dong, C., Jan 1 2015, In : Cellular and Molecular Bioengineering. 8, 1, p. 86-95 10 p.

Research output: Contribution to journalArticle

Melanoma
Shear flow
Shear Flow
Adhesion
Receptor
3 Citations (Scopus)

Regulation of fibrin-mediated tumor cell adhesion to the endothelium using anti-thrombin aptamer

Gaddes, E. R., Lee, D., Gydush, G., Wang, Y. & Dong, C., Dec 1 2015, In : Experimental Cell Research. 339, 2, p. 417-426 10 p.

Research output: Contribution to journalArticle

Fibrin
Cell Adhesion
Endothelium
Thrombin
Fibrinogen
2014
34 Citations (Scopus)

Aptamer-functionalized superporous hydrogels for sequestration and release of growth factors regulated via molecular recognition

Battig, M. R., Huang, Y., Chen, N. & Wang, Y., Sep 2014, In : Biomaterials. 35, 27, p. 8040-8048 9 p.

Research output: Contribution to journalArticle

Molecular recognition
Hydrogels
Biological Products
Intercellular Signaling Peptides and Proteins
Hydrogel
12 Citations (Scopus)

Bioinspired affinity DNA polymers on nanoparticles for drug sequestration and detoxification

Chen, N., Huang, Y. & Wang, Y., Jan 1 2014, In : Biomaterials. 35, 36, p. 9709-9718 10 p.

Research output: Contribution to journalArticle

Detoxification
Nanostructures
Nanostructured materials
Nanoparticles
Polymers
8 Citations (Scopus)

Polymerization of affinity ligands on a surface for enhanced ligand display and cell binding

Richards, E., Li, S., Chen, N., Battig, M. R. & Wang, Y., Dec 8 2014, In : Biomacromolecules. 15, 12, p. 4561-4569 9 p.

Research output: Contribution to journalArticle

Display devices
Ligands
Polymerization
Surface reactions
Polymers
2013
11 Citations (Scopus)

DNA gold nanoparticle nanocomposite films for chemiresistive vapor sensing

Fu, K., Li, S., Jiang, X., Wang, Y. & Willis, B. G., Nov 19 2013, In : Langmuir. 29, 46, p. 14335-14343 9 p.

Research output: Contribution to journalArticle

Nanocomposite films
Gold
humidity
Atmospheric humidity
nanocomposites
47 Citations (Scopus)

Endonuclease-responsive aptamer-functionalized hydrogel coating for sequential catch and release of cancer cells

Li, S., Chen, N., Zhang, Z. & Wang, Y., Jan 1 2013, In : Biomaterials. 34, 2, p. 460-469 10 p.

Research output: Contribution to journalArticle

Hydrogel
Endonucleases
Hydrogels
Cells
Circulating Neoplastic Cells
11 Citations (Scopus)

Programmable display of DNA-protein chimeras for controlling cell-hydrogel interactions via reversible intermolecular hybridization

Zhang, Z., Li, S., Chen, N., Yang, C. & Wang, Y., Apr 8 2013, In : Biomacromolecules. 14, 4, p. 1174-1180 7 p.

Research output: Contribution to journalArticle

Hydrogel
Hydrogels
DNA
Display devices
Proteins
6 Citations (Scopus)

Programmable hydrogels for the controlled release of therapeutic nucleic acid aptamers via reversible DNA hybridization

Zhang, X., Battig, M. R. & Wang, Y., Oct 25 2013, In : Chemical Communications. 49, 83, p. 9600-9602 3 p.

Research output: Contribution to journalArticle

Hydrogels
Oligonucleotides
Nucleic acids
Nucleic Acids
DNA
7 Citations (Scopus)

Programmable imaging amplification via nanoparticle-initiated DNA polymerization

Chen, N., Li, S., Battig, M. R. & Wang, Y., Dec 9 2013, In : Small. 9, 23, p. 3944-3949 6 p.

Research output: Contribution to journalArticle

Polymerization
Nanoparticles
Amplification
DNA
Imaging techniques
2012
50 Citations (Scopus)

Cell adhesion on an artificial extracellular matrix using aptamer-functionalized PEG hydrogels

Chen, N., Zhang, Z., Soontornworajit, B., Zhou, J. & Wang, Y., Feb 1 2012, In : Biomaterials. 33, 5, p. 1353-1362 10 p.

Research output: Contribution to journalArticle

Hydrogels
Cell adhesion
Cell Adhesion
Polyethylene glycols
Extracellular Matrix
20 Citations (Scopus)

Enhanced loading and controlled release of antibiotics using nucleic acids as an antibiotic-binding effector in hydrogels

Zhang, X., Soontornworajit, B., Zhang, Z., Chen, N. & Wang, Y., Jul 9 2012, In : Biomacromolecules. 13, 7, p. 2202-2210 9 p.

Research output: Contribution to journalArticle

Hydrogels
Oligonucleotides
Nucleic acids
Antibiotics
Nucleic Acids
89 Citations (Scopus)

Programmable hydrogels for controlled cell catch and release using hybridized aptamers and complementary sequences

Zhang, Z., Chen, N., Li, S., Battig, M. R. & Wang, Y., Sep 26 2012, In : Journal of the American Chemical Society. 134, 38, p. 15716-15719 4 p.

Research output: Contribution to journalArticle

Hydrogels
Hydrogel
Regenerative Medicine
Cell Separation
Cell Communication
79 Citations (Scopus)

Programmable release of multiple protein drugs from aptamer-functionalized hydrogels via nucleic acid hybridization

Battig, M. R., Soontornworajit, B. & Wang, Y., Aug 1 2012, In : Journal of the American Chemical Society. 134, 30, p. 12410-12413 4 p.

Research output: Contribution to journalArticle

Nucleic Acid Hybridization
Hydrogels
Nucleic acids
Nucleic Acids
Proteins
2011
37 Citations (Scopus)

Affinity hydrogels for controlled protein release using nucleic acid aptamers and complementary oligonucleotides

Soontornworajit, B., Zhou, J., Snipes, M. P., Battig, M. R. & Wang, Y., Oct 1 2011, In : Biomaterials. 32, 28, p. 6839-6849 11 p.

Research output: Contribution to journalArticle

Hydrogels
Oligonucleotides
Nucleic acids
Nucleic Acids
Proteins
5 Citations (Scopus)

An aptamer-functionalized hydrogel for controlled protein release: A modeling study

Fan, T. H., Soontornworajit, B., Karzar-Jeddi, M., Zhang, X. & Wang, Y., Oct 7 2011, In : Soft Matter. 7, 19, p. 9326-9334 9 p.

Research output: Contribution to journalArticle

Hydrogel
proteins
Kinetics
kinetics
Proteins
68 Citations (Scopus)

Folate-functionalized unimolecular micelles based on a degradable amphiphilic dendrimer-like star polymer for cancer cell-targeted drug delivery

Cao, W., Zhou, J., Mann, A., Wang, Y. & Zhu, L., Jul 11 2011, In : Biomacromolecules. 12, 7, p. 2697-2707 11 p.

Research output: Contribution to journalArticle

Dendrimers
Micelles
Folic Acid
Stars
Polymers
12 Citations (Scopus)

Structural prediction and binding analysis of hybridized aptamers

Zhou, J., Soontornworajit, B., Snipes, M. P. & Wang, Y., Jan 1 2011, In : Journal of Molecular Recognition. 24, 1, p. 119-126 8 p.

Research output: Contribution to journalArticle

Research
2010
35 Citations (Scopus)

A hybrid particle-hydrogel composite for oligonucleotide-mediated pulsatile protein release

Soontornworajit, B., Zhou, J. & Wang, Y., Sep 7 2010, In : Soft Matter. 6, 17, p. 4255-4261 7 p.

Research output: Contribution to journalArticle

oligonucleotides
Hydrogel
Oligonucleotides
proteins
composite materials
53 Citations (Scopus)

Aptamer-functionalized in situ injectable hydrogel for controlled protein release

Soontornworajit, B., Zhou, J., Zhang, Z. & Wang, Y., Oct 11 2010, In : Biomacromolecules. 11, 10, p. 2724-2730 7 p.

Research output: Contribution to journalArticle

Hydrogel
Hydrogels
Proteins
Nucleotides
Nucleic Acids
18 Citations (Scopus)

A temperature-responsive antibody-like nanostructure

Zhou, J., Soontornworajit, B. & Wang, Y., Aug 9 2010, In : Biomacromolecules. 11, 8, p. 2087-2093 7 p.

Research output: Contribution to journalArticle

Antibodies
Nanostructures
Dendrimers
Temperature
Antigens
76 Citations (Scopus)

Hydrogel functionalization with DNA aptamers for sustained PDGF-BB release

Soontornworajit, B., Zhou, J., Shaw, M. T., Fan, T. H. & Wang, Y., Mar 19 2010, In : Chemical Communications. 46, 11, p. 1857-1859 3 p.

Research output: Contribution to journalArticle

Nucleotide Aptamers
Hydrogel
Hydrogels
DNA
platelet-derived growth factor BB
39 Citations (Scopus)

Synthesis and in vitro cancer cell targeting of folate-functionalized biodegradable amphiphilic dendrimer-like star polymers

Cao, W., Zhou, J., Wang, Y. & Zhu, L., Dec 13 2010, In : Biomacromolecules. 11, 12, p. 3680-3687 8 p.

Research output: Contribution to journalArticle

Dendrimers
Folic Acid
Stars
Polymers
Cells
2009
30 Citations (Scopus)

A hybrid DNA aptamer-dendrimer nanomaterial for targeted cell labeling

Zhou, J., Soontornworajit, B., Martin, J., Sullenger, B. A., Gilboa, E. & Wang, Y., Sep 9 2009, In : Macromolecular Bioscience. 9, 9, p. 831-835 5 p.

Research output: Contribution to journalArticle

Nucleotide Aptamers
Dendrimers
Nanostructures
Nanostructured materials
Labeling
10 Citations (Scopus)

Development of a novel pretargeting system with bifunctional nucleic acid molecules

Zhou, J., Soontornworajit, B., Snipes, M. P. & Wang, Y., Aug 28 2009, In : Biochemical and Biophysical Research Communications. 386, 3, p. 521-525 5 p.

Research output: Contribution to journalArticle

Nucleic Acids
Molecules
Oligonucleotides
Labeling
1 Citation (Scopus)

Nanoporous membrane-encapsulated feeder cells for culture of human embryonic stem cells

Zhou, J., Xu, R. H. & Wang, Y., Jan 1 2009, In : International Journal of Functional Informatics and Personalised Medicine. 2, 1, p. 77-88 12 p.

Research output: Contribution to journalArticle

Feeder Cells
Cell Culture Techniques
Membranes
Coculture Techniques
Conditioned Culture Medium
2007
14 Citations (Scopus)

Transscleral diffusion of ethacrynic acid and sodium fluorescein

Lin, C. W., Wang, Y., Challa, P., Epstein, D. L. & Yuan, F., Feb 22 2007, In : Molecular vision. 13, p. 243-251 9 p.

Research output: Contribution to journalArticle

Ethacrynic Acid
Fluorescein
Sclera
Trabecular Meshwork
Pharmaceutical Preparations
2006
745 Citations (Scopus)

Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

McNamara, J. O., Andrechek, E. R., Wang, Y., Viles, K. D., Rempel, R. E., Gilboa, E., Sullenger, B. A. & Giangrande, P. H., Aug 1 2006, In : Nature Biotechnology. 24, 8, p. 1005-1015 11 p.

Research output: Contribution to journalArticle

Nucleotide Aptamers
RNA
Small Interfering RNA
Tumors
Cells
54 Citations (Scopus)
Tumors
Cells
Genes
Tissue
Proteins
25 Citations (Scopus)

Effects of rate, volume, and dose of intratumoral infusion on virus dissemination in local gene delivery

Wang, Y., Wang, H., Li, C. Y. & Yuan, F., Feb 1 2006, In : Molecular cancer therapeutics. 5, 2, p. 362-366 5 p.

Research output: Contribution to journalArticle

Luciferases
Viruses
Genes
Neoplasms
Transgenes
2005
4 Citations (Scopus)

Alginate encapsulation is a highly reproducible method for tumor cell implantation in dorsal skinfold chambers

Wang, Y., Chen, Q. & Yuan, F., Dec 1 2005, In : BioTechniques. 39, 6, p. 834-838 5 p.

Research output: Contribution to journalArticle

Hexuronic Acids
Alginates
Glucuronic Acid
Encapsulation
Tumors
45 Citations (Scopus)

A novel method for viral gene delivery in solid tumors

Wang, Y., Liu, S., Li, C. Y. & Yuan, F., Sep 1 2005, In : Cancer Research. 65, 17, p. 7541-7545 5 p.

Research output: Contribution to journalArticle

Viral Genes
Poloxamer
Neoplasms
Oncogenic Viruses
Convection