• 832 Citations
  • 14 h-Index
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Personal profile

Research interests

The main interest of Dr. Yongsoo Kim’s lab is to understand structural and functional organization of the mammalian brain using mice as an animal model. Particularly, Dr. Kim is interested in understanding the neural circuit basis of social behavior and its dysfunction in brain disorders. Social behavior is complex, requiring the integration of multiple sensory modalities, internal state information and memories of prior experience in order to generate highly nuanced responses to diverse environmental scenarios. Impairment of social behavior occurs often in many neurodevelopmental and psychiatric disorders.

Thus, the Kim lab’s goal is to understand how local and brain-wide neural network operate to generate normal social behavior and how such processes are altered in pathological conditions. Toward that goal, Dr. Kim’s lab uses an automated 3D microscopy system called serial two-photon tomography to image whole mouse brains with cellular resolution. Dr. Kim used this imaging method with sophisticated data processing pipeline to systematically analyze target signals in the entire mouse brain. Previously, he used this method to perform cFos-based neural activity mapping, quantitative cell type mapping and brain-wide axonal projection mapping.

Currently, Dr. Kim’s lab is developing three-dimensional digital mouse brain atlases across different ages to establish a bioinformatics solution to register detected signals. Using the digital map, he is working on mapping oxytocin and oxytocin receptor-expressing neurons that play an essential role in generating and regulating social behavior. Moreover, he is also working on generating a detailed three-dimensional structure of microvaculature in the whole mouse brain.

Education/Academic qualification

Postdoctoral Training, Cold Spring Harbor Laboratory


Visiting Student, University of Oxford


PhD, Northwestern University


BS, Seoul National University


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Stem Cells Medicine & Life Sciences
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GABAergic Neurons Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2007 2019

  • 832 Citations
  • 14 h-Index
  • 17 Article
  • 1 Comment/debate
  • 1 Review article

Enhanced and unified anatomical labeling for a common mouse brain atlas

Chon, U., Vanselow, D. J., Cheng, K. C. & Kim, Y., Dec 1 2019, In : Nature communications. 10, 1, 5067.

Research output: Contribution to journalArticle

Open Access

The A30P α-synuclein mutation decreases subventricular zone proliferation

Zhang, X. M., Anwar, S., Kim, Y., Brown, J., Comte, I., Cai, H., Cai, N. N., Wade-Martins, R. & Szele, F. G., Jul 15 2019, In : Human Molecular Genetics. 28, 14, p. 2283-2294 12 p., ddz057.

Research output: Contribution to journalArticle

Lateral Ventricles
Olfactory Bulb
Parkinson Disease
6 Citations (Scopus)

Radial Glial Lineage Progression and Differential Intermediate Progenitor Amplification Underlie Striatal Compartments and Circuit Organization

Kelly, S. M., Raudales, R., He, M., Lee, J. H., Kim, Y., Gibb, L. G., Wu, P., Matho, K., Osten, P., Graybiel, A. M. & Huang, Z. J., Jul 25 2018, In : Neuron. 99, 2, p. 345-361.e4

Research output: Contribution to journalArticle

Corpus Striatum
Basal Ganglia
21 Citations (Scopus)

Subset of cortical layer 6b neurons selectively innervates higher order thalamic nuclei in mice

Hoerder-Suabedissen, A., Hayashi, S., Upton, L., Nolan, Z., Casas-Torremocha, D., Grant, E., Viswanathan, S., Kanold, P. O., Clasca, F., Kim, Y. & Molnár, Z., Jan 1 2018, In : Cerebral Cortex. 28, 5, p. 1882-1897 16 p.

Research output: Contribution to journalArticle

Thalamic Nuclei
Somatosensory Cortex
Posterior Thalamic Nuclei
33 Citations (Scopus)

Brain-wide Maps Reveal Stereotyped Cell-Type-Based Cortical Architecture and Subcortical Sexual Dimorphism

Kim, Y., Yang, G. R., Pradhan, K., Venkataraju, K. U., Bota, M., García del Molino, L. C., Fitzgerald, G., Ram, K., He, M., Levine, J. M., Mitra, P., Huang, Z. J., Wang, X. J. & Osten, P., Oct 5 2017, In : Cell. 171, 2, p. 456-469.e22

Research output: Contribution to journalArticle

Sex Characteristics
Brain Mapping


Junior Faculty Research Scholar Award

Yongsoo Kim (Recipient), 2018

Prize: Honorary award

Korean Government Overseas Scholarship

Yongsoo Kim (Recipient), 2004

Prize: Honorary award

NARSAD Young Investigator Award

Yongsoo Kim (Recipient), 2013

Prize: Honorary award