Zafer Hatahet

Division Head, Division of Engineering and Science (Abington)

2062 Citations
20 h-Index

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Deoxyribonuclease (Pyrimidine Dimer) Medicine & Life Sciences

DNA-Formamidopyrimidine Glycosylase Medicine & Life Sciences

Escherichia coli Medicine & Life Sciences

DNA Medicine & Life Sciences

DNA-Directed DNA Polymerase Medicine & Life Sciences

Endonucleases Medicine & Life Sciences

DNA Glycosylases Medicine & Life Sciences

Nucleotides Medicine & Life Sciences

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Projects 1990 2003

1 Finished
1 Active

SMALL INSTRUMENTATION GRANT

Hatahet, Z. & Ley, R.

National Institutes of Health

7/15/90 → …

Project: Research project

PROCESSING OF OXIDATIVE DNA LESIONS--TRANSIENT KINETICS

Hatahet, Z.

National Institutes of Health

4/1/98 → 9/30/03

Project: Research project

DNA-Directed DNA Polymerase

Kinetics

DNA

Processing

Repair

Research Output 1989 2015

2062 Citations
20 h-Index
25 Article

12 Citations (Scopus)

Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities

Chen, Y. W., Harris, R. A., Hatahet, Z. & Chou, K. M., Aug 18 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 33, p. E4556-E4564

Research output: Contribution to journal › Article

DNA Damage

Adipose Tissue

Adipocytes

Genes

Obesity

44 Citations (Scopus)

Human DNA polymerase η activity and translocation is regulated by phosphorylation

Chen, Y. W., Cleaver, J. E., Hatahet, Z., Honkanen, R. E., Chang, J. Y., Yen, Y. & Chou, K. M., Oct 28 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 43, p. 16578-16583 6 p.

Research output: Contribution to journal › Article

gemcitabine

DNA-Directed DNA Polymerase

Phosphorylation

Cisplatin

Protein Interaction Domains and Motifs

89 Citations (Scopus)

Human DNA polymerase κ bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides

Fischhaber, P. L., Gerlach, V. L., Feaver, W. J., Hatahet, Z., Wallace, S. S. & Friedberg, E. C., Oct 4 2002, In : Journal of Biological Chemistry. 277, 40, p. 37604-37611 8 p.

Research output: Contribution to journal › Article

DNA-Directed DNA Polymerase

Nucleotides

Stereoisomerism

Guanine

Adenine

244 Citations (Scopus)

Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions

Hazra, T. K., Kow, Y. W., Hatahet, Z., Imhoff, B., Boldogh, I., Mokkapati, S. K., Mitra, S. & Izumi, T., Aug 23 2002, In : Journal of Biological Chemistry. 277, 34, p. 30417-30420 4 p.

Research output: Contribution to journal › Article

DNA Glycosylases

Cytosine

DNA Repair

Escherichia coli

Repair

A novel role for Escherichia coli endonuclease VIII in prevention of spontaneous G → T transversions

Blaisdell, J. O., Hatahet, Z. & Wallace, S. S., Oct 1 1999, In : Journal of bacteriology. 181, 20, p. 6396-6402 7 p.

Research output: Contribution to journal › Article

Deoxyribonuclease (Pyrimidine Dimer)

DNA-Formamidopyrimidine Glycosylase

DNA Glycosylases

Escherichia coli

Mutation