• 2570 Citations
  • 19 h-Index
19992019

Research output per year

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Research Output

  • 2570 Citations
  • 19 h-Index
  • 22 Article
Article

2-Anilino-4-aryl-1,3-thiazole inhibitors of valosin-containing protein (VCP or p97)

Bursavich, M. G., Parker, D. P., Willardsen, J. A., Gao, Z., Davis, T., Ostanin, K., Robinson, R., Peterson, A., Cimbora, D. M., Zhu, J. F. & Richards, B., Mar 1 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 5, p. 1677-1679 3 p.

Research output: Contribution to journalArticle

46 Scopus citations

A dimeric Smac/Diablo peptide directly relieves caspase-3 inhibition by XIAP: Dynamic and cooperative regulation of XIAP by Smac/Diablo

Gao, Z., Tian, Y., Wang, J., Yin, Q., Wu, H., Li, Y. M. & Jiang, X., Oct 19 2007, In : Journal of Biological Chemistry. 282, 42, p. 30718-30727 10 p.

Research output: Contribution to journalArticle

81 Scopus citations

Analogues of 4-[(7-Bromo-2-methyl-4-oxo-3 H -quinazolin-6-yl)methylprop-2- ynylamino]- N -(3-pyridylmethyl)benzamide (CB-30865) as potent inhibitors of nicotinamide phosphoribosyltransferase (Nampt)

Lockman, J. W., Murphy, B. R., Zigar, D. F., Judd, W. R., Slattum, P. M., Gao, Z. H., Ostanin, K., Green, J., McKinnon, R., Terry-Lorenzo, R. T., Fleischer, T. C., Boniface, J. J., Shenderovich, M. & Willardsen, J. A., Dec 23 2010, In : Journal of Medicinal Chemistry. 53, 24, p. 8734-8746 13 p.

Research output: Contribution to journalArticle

23 Scopus citations

An AUTS2-Polycomb complex activates gene expression in the CNS

Gao, Z., Lee, P., Stafford, J. M., Schimmelmann, M. V., Schaefer, A. & Reinberg, D., Dec 18 2014, In : Nature. 516, 7531, p. 349-354 6 p.

Research output: Contribution to journalArticle

107 Scopus citations

Apoptotic and autophagic cell death induced by histone deacetylase inhibitors

Shao, Y., Gao, Z., Marks, P. A. & Jiang, X., Dec 28 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 52, p. 18030-18035 6 p.

Research output: Contribution to journalArticle

471 Scopus citations

A Wnt-CKIε-Rap1 Pathway Regulates Gastrulation by Modulating SIPA1L1, a Rap GTPase Activating Protein

Tsai, I. C., Amack, J. D., Gao, Z. H., Band, V., Yost, H. J. & Virshup, D. M., Mar 1 2007, In : Developmental Cell. 12, 3, p. 335-347 13 p.

Research output: Contribution to journalArticle

54 Scopus citations

Calcineurin B- and calmodulin-binding preferences identified with phage- displayed peptide libraries

Gao, Z. & Zhong, G., Mar 4 1999, In : Gene. 228, 1-2, p. 51-59 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Casein kinase I phosphorylates and destabilizes the β-catenin degradation complex

Gao, Z. H., Seeling, J. M., Hill, V., Yochum, A. & Virshup, D. M., Feb 5 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 3, p. 1182-1187 6 p.

Research output: Contribution to journalArticle

176 Scopus citations

Chemical Proteomics Identifies Nampt as the Target of CB30865, An Orphan Cytotoxic Compound

Fleischer, T. C., Murphy, B. R., Flick, J. S., Terry-Lorenzo, R. T., Gao, Z. H., Davis, T., McKinnon, R., Ostanin, K., Willardsen, J. A. & Boniface, J. J., Jun 25 2010, In : Chemistry and Biology. 17, 6, p. 659-664 6 p.

Research output: Contribution to journalArticle

43 Scopus citations

Essential roles of the Bcl-2 family of proteins in caspase-2-induced apoptosis

Gao, Z., Shao, Y. & Jiang, X., Dec 1 2005, In : Journal of Biological Chemistry. 280, 46, p. 38271-38275 5 p.

Research output: Contribution to journalArticle

62 Scopus citations

Identification of casein kinase I substrates by in vitro expression cloning screening

Gao, Z. H., Metherall, J. & Virshup, D. M., Feb 16 2000, In : Biochemical and Biophysical Research Communications. 268, 2, p. 562-566 5 p.

Research output: Contribution to journalArticle

24 Scopus citations

L3MBTL2 Protein Acts in Concert with PcG Protein-Mediated Monoubiquitination of H2A to Establish a Repressive Chromatin Structure

Trojer, P., Cao, A. R., Gao, Z., Li, Y., Zhang, J., Xu, X., Li, G., Losson, R., Erdjument-Bromage, H., Tempst, P., Farnham, P. J. & Reinberg, D., May 20 2011, In : Molecular cell. 42, 4, p. 438-450 13 p.

Research output: Contribution to journalArticle

82 Scopus citations

Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway

Chen, S., Wang, Q., Yu, H., Capitano, M. L., Vemula, S., Nabinger, S. C., Gao, R., Yao, C., Kobayashi, M., Geng, Z., Fahey, A., Henley, D., Liu, S. Z., Barajas, S., Cai, W., Wolf, E. R., Ramdas, B., Cai, Z., Gao, H., Luo, N. & 12 others, Sun, Y., Wong, T. N., Link, D. C., Liu, Y., Boswell, H. S., Mayo, L. D., Huang, G., Kapur, R., Yoder, M. C., Broxmeyer, H. E., Gao, Z. & Liu, Y., Dec 1 2019, In : Nature communications. 10, 1, 5649.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

NEDD4-1 Is a Proto-Oncogenic Ubiquitin Ligase for PTEN

Wang, X., Trotman, L. C., Koppie, T., Alimonti, A., Chen, Z., Gao, Z., Wang, J., Erdjument-Bromage, H., Tempst, P., Cordon-Cardo, C., Pandolfi, P. P. & Jiang, X., Jan 12 2007, In : Cell. 128, 1, p. 129-139 11 p.

Research output: Contribution to journalArticle

463 Scopus citations

Nuclear entry of the circadian regulator MPER1 is controlled by mammalian casein kinase I ε

Vielhaber, E., Eide, E., Rivers, A., Gao, Z. H. & Virshup, D. M., Jul 1 2000, In : Molecular and cellular biology. 20, 13, p. 4888-4899 12 p.

Research output: Contribution to journalArticle

225 Scopus citations

PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes

Gao, Z., Zhang, J., Bonasio, R., Strino, F., Sawai, A., Parisi, F., Kluger, Y. & Reinberg, D., Feb 10 2012, In : Molecular cell. 45, 3, p. 344-356 13 p.

Research output: Contribution to journalArticle

427 Scopus citations

Processing of autophagic protein LC3 by the 20S proteasome

Gao, Z., Gammoh, N., Wong, P. M., Erdjument-Bromage, H., Tempst, P. & Jiang, X., Jan 1 2010, In : Autophagy. 6, 1, p. 126-137 12 p.

Research output: Contribution to journalArticle

64 Scopus citations

Regulation of Kir Channels by Intracellular pH and Extracellular K+: Mechanisms of Coupling

Dahlmann, A., Li, M., Gao, Z. H., McGarrigle, D., Sackin, H. & Palmer, L. G., Apr 1 2004, In : Journal of General Physiology. 123, 4, p. 441-454 14 p.

Research output: Contribution to journalArticle

28 Scopus citations

Stimulation of ATG12-ATG5 conjugation by ribonucleic acid

Shao, Y., Gao, Z., Feldman, T. & Jiang, X., Jan 1 2007, In : Autophagy. 3, 1, p. 10-16 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

The program for processing newly synthesized histones H3.1 and H4

Campos, E. I., Fillingham, J., Li, G., Zheng, H., Voigt, P., Kuo, W. H. W., Seepany, H., Gao, Z., Day, L. A., Greenblatt, J. F. & Reinberg, D., Nov 1 2010, In : Nature Structural and Molecular Biology. 17, 11, p. 1343-1351 9 p.

Research output: Contribution to journalArticle

134 Scopus citations

There is communication between all four Ca2+-bindings sites of calcineurin B

Gallagher, S. C., Gao, Z. H., Li, S., Dyer, R. B., Trewhella, J. & Klee, C. B., Oct 9 2001, In : Biochemistry. 40, 40, p. 12094-12102 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

WDR68 is essential for the transcriptional activation of the PRC1-AUTS2 complex and neuronal differentiation of mouse embryonic stem cells

Wang, Q., Geng, Z., Gong, Y., Warren, K., Zheng, H., Imamura, Y. & Gao, Z., Dec 2018, In : Stem Cell Research. 33, p. 206-214 9 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations