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Activation of the Ah receptor and epithelial integrity

Perdew, G. H.

National Institutes of Health

9/15/175/31/25

Project: Research projectOutstanding Investigator Award

Ligands
Artificial Receptors
Skin
Chronic Disease
Diet

Pathways to Health from Adolescence through Young Adulthood

Feinberg, M. E. & Fosco, G.

National Institutes of Health

9/12/176/30/22

Project: Research projectResearch Project

Social Adjustment
Health
House Calls
Family Relations
Mental Competency
Tight Junctions
Autophagy
Inflammation
Inflammatory Bowel Diseases
Tight Junction Proteins
Gingiva
Mesenchymal Stromal Cells
Arthritis
Cartilage
Rheumatoid Arthritis
Aryl Hydrocarbon Receptors
Microbiota
Ligands
3,4,5,3',4'-pentachlorobiphenyl
Ceramides

Autophagy, Inflammation and Metabolism (AIM) in Disease Center

Nighot, P., Sklar, L. A., Mandell, M. A., Yang, X., Prossnitz, E., Meilian, L. & Deretic, V.

National Institutes of Health

9/1/178/31/22

Project: Research projectExploratory Grants

Tight Junctions
Autophagy
Inflammation
Inflammatory Bowel Diseases
Claudin-2
Epigenomics
Genome
Cell Line
Gene Expression
Inborn Genetic Diseases
Homeostasis
Lymphocytes
Inflammation
Skin
Chemokine Receptors

Physiology of ribosome rescue in bacteria

Keiler, K. C.

National Institutes of Health

8/1/174/30/21

Project: Research projectResearch Project

Ribosomes
Bacteria
Bacterial Physiological Phenomena
Francisella tularensis
Anti-Bacterial Agents
Dissection
Magnetic Resonance Imaging
Electrophysiology
Optogenetics
Photometry

Ribozyme Guided CRISPRi in Human- and Rodent-Infectious Plasmodium species

Lindner, S. E.

National Institutes of Health

7/12/176/30/19

Project: Research projectExploratory/Developmental Grants

Catalytic RNA
Plasmodium
Rodentia
Parasites
Genes
Dietary Fiber
Hepatocellular Carcinoma
Toll-Like Receptor 5
Inulin
Dysbiosis
Neurogenesis
Olfactory Bulb
Olfactory Receptor Neurons
Automatic Data Processing
Neurons

A simple, genetically tractable model for axon initial segment function

Jegla, T. J. & Rolls, M.

National Institutes of Health

7/1/176/30/19

Project: Research projectExploratory/Developmental Grants

Ion Channels
Drosophila
Vertebrates
Sensory Receptor Cells
Axons

Tuning big data analysis infrastructure for HIV research

Nekrutenko, A., Taylor, J. P. & Pond, S. L. K.

National Institutes of Health

6/26/175/31/22

Project: Research projectResearch Project

Tuning
Genes
Big data
Costs
Breast Neoplasms
Oncogenes
Breast
Neoplasm Genes
Genetic Association Studies

Resistance Training to Reduce Chemotoxicity in Colon Cancer

Schmitz, K., Caan, B. & Meyerhardt, J.

National Institutes of Health

6/15/175/31/22

Project: Research projectResearch Project

Resistance Training
Colonic Neoplasms
Muscles
Drug Therapy
Sarcopenia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Drug Resistance
Leukemia
B-Lymphocytes
Folic Acid

Interferon-independent STAT1-mediated protective antiviral immunity

Norbury, C.

National Institutes of Health

6/5/175/31/19

Project: Research projectExploratory/Developmental Grants

Interferons
Antiviral Agents
Immunity
Vaccinia virus
Interferon Receptors

Cationic Bolaamphiphiles (CAB) and Phosphorothioate Gapmers as Antisense Therapy for C. difficile

Sharma, A. & Stewart, D. B.

National Institutes of Health

6/5/175/31/19

Project: Research projectExploratory/Developmental Grants

Infection
Anti-Bacterial Agents
Therapeutics
Bacteria
bolaamphiphile

Coparenting, Infant Sleep, and Infant Development

Teti, D. M.

National Institutes of Health

6/1/172/28/22

Project: Research projectResearch Project

Child Development
Sleep
Parenting
Social Adjustment
Mothers

Dissecting RNA Regulation During Malaria Parasite Sexual Development

Llinas, M.

National Institutes of Health

6/1/175/31/19

Project: Research projectExploratory/Developmental Grants

Sexual Development
RNA-Binding Proteins
Malaria
Parasites
RNA

Midwest Consortium for High Resolution Cryoelectron Microscopy

Hafenstein, S., Parent, K., Stowell, M. H. B., Taylor, D. J., Bullitt, E., Ruiz, T., Samso, M., White, T. A., Dai, W. E. I., Tang, L., Dokland, T. & Jiang, W. E. N.

National Institutes of Health

6/1/175/31/22

Project: Research projectResource-Related Research Projects--Cooperative Agreements

electron microscopy
microscopy
high resolution
electron counters
resources
Toll-Like Receptors
MicroRNAs
Autoimmunity
B-Lymphocytes
Systemic Lupus Erythematosus
Biosynthesis
Biological Products
Oxazoles
Anti-Bacterial Agents
Thiazoles
nutrition situation
food
assistance
parents
homeless family

Gene delivery for Anopheles mosquitoes

Rasgon, J. L.

National Institutes of Health

5/10/174/30/22

Project: Research projectResearch Project

Anopheles
Anopheles gambiae
Culicidae
Malaria
Densovirus
Alzheimer Disease
Affective Symptoms
Memory Disorders
Reproducibility of Results

Engineering allostery for in vivo protein control

Dokholyan, N.

National Institutes of Health

5/1/173/31/21

Project: Research projectResearch Project

Allosteric Regulation
Protein Interaction Maps
Guanine
Proteins
Guanosine Triphosphate

Radical Mechanisms of Iron-Sulfur Proteins

Booker, S. J.

National Institutes of Health

4/1/173/31/22

Project: Research projectOutstanding Investigator Award

Iron-Sulfur Proteins
S-Adenosylmethionine
Biosynthesis
Sulfur
Enzymes

Examining the Impact of Students' Motives on Comorbid Alcohol and Drug Use

Mallett, K. A.

National Institutes of Health

4/1/173/31/19

Project: Research projectExploratory/Developmental Grants

Alcohols
Students
Pharmaceutical Preparations
Risk-Taking
Public Health
Major Depressive Disorder
Depression
Nitric Oxide
Cardiovascular Diseases
Blood Vessels

Multimotor Mechanisms in Microtubule-based Transport

Hancock, W. O.

National Institutes of Health

4/1/171/31/21

Project: Research projectResearch Project

Kinesin
Microtubules
Dyneins
Cytoplasmic Dyneins
Axonal Transport

Environmental Ah Receptor Ligand Impact on the Host-Microbiome Metabolic Axis

Patterson, A. D.

National Institutes of Health

3/1/172/28/19

Project: Research projectHigh Priority, Short Term Project Award

Aryl Hydrocarbon Receptors
Microbiota
Ligands
Ceramides
Germ-Free Life

Production of a humanized Ah receptor mouse line

Perdew, G. H.

National Institutes of Health

3/1/172/28/19

Project: Research projectSmall Research Grants

Aryl Hydrocarbon Receptors
Citrobacter rodentium
Homeostasis
Complementary DNA
Ligands
Homeostasis
Lymphocytes
Skin
Dermatitis
Psoriasis

Acute and Chronic Afferent Engagement: Sympathetic and End Organ Responses

Li, J., Ruiz-Velasco, V., Kaufman, M. & Sinoway, L.

National Institutes of Health

2/1/171/31/22

Project: Research projectResearch Program Projects

Peripheral Arterial Disease
Reflex
Muscles
Femoral Artery
Exercise

Study of Anti-Malarials in Incomplete Lupus Erythematosus (SMILE)

Olsen, N. & Karp, D.

National Institutes of Health

2/1/171/31/22

Project: Research projectResearch Project--Cooperative Agreements

Hydroxychloroquine
Antimalarials
Systemic Lupus Erythematosus
Health Services Needs and Demand
Antinuclear Antibodies
Modifier Genes
Inborn Genetic Diseases
Autistic Disorder
Xenopus
Drosophila melanogaster

Regulation of TAL1/SCL in T-Cell Leukemia

Huang, S.

National Institutes of Health

2/1/171/31/22

Project: Research projectResearch Project

T-Cell Leukemia
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Oncogenes
Hematopoiesis
Leukemia

Genomic analysis of HSV-1 in the niche of genital infection

Szpara, M. L.

National Institutes of Health

1/16/1712/31/18

Project: Research projectExploratory/Developmental Grants

Human Herpesvirus 1
Infection
Herpes Genitalis
Genome
Viral Genome
Alcohols
Hispanic Americans
Public Health
Research
Aptitude

Mechanistic study of pioneer factors

Bai, L.

National Institutes of Health

1/1/1712/31/20

Project: Research projectResearch Project

Nucleosomes
Transcription Factors
Regulator Genes
Chromosomes
Binding Sites
Vision Disorders
Veterans
Rehabilitation
Parietal Lobe
Imagery (Psychotherapy)

Molecular Mechanisms of Artemisinin Resistance

Cui, L.

National Institutes of Health

12/13/1611/30/21

Project: Research projectResearch Project

Plasmodium falciparum
Myanmar
China
Southeastern Asia
Parasites

Nitric oxide and microvessel permeability in vivo

He, P.

National Institutes of Health

12/12/1611/30/20

Project: Research projectResearch Project

Microvessels
Permeability
Reactive Oxygen Species
Nitric Oxide
Peroxynitrous Acid
Plasmodium
Parasites
Sporozoites
Messenger RNA
Proteins

The Early Growth and Development Study Pediatric Cohort

Neiderhiser, J. M., Leve, L. D. & Ganiban, J. M.

National Institutes of Health

9/21/168/31/23

Project: Research projectExploratory/Developmental Cooperative Agreement Phase II

Growth and Development
Cohort Studies
Pediatrics
Siblings
Social Environment

Mucosal Macrophages and Post-Infectious IBD

Bogunovic, M.

National Institutes of Health

9/16/168/31/21

Project: Research projectResearch Project

Inflammatory Bowel Diseases
Antigen-Presenting Cells
Macrophages
T-Lymphocytes
Anti-Inflammatory Agents

Penn State Clinical and Translational Science Institute

Sinoway, L.

National Institutes of Health

9/15/165/31/20

Project: Research projectLinked Specialized Center Cooperative Agreement

Health
Ethics
Suburban Population
Research
Research Personnel