ANATOMICAL BASIS OF VISION

  • Eslinger, Paul (PI)
  • Eslinger, Paul (PI)
  • DAMASIO, ANTONIO (PI)
  • DAMASIO, ANTONIO (PI)
  • DAMASIO, ANTONIO (PI)
  • Rizzo, Matthew (PI)
  • TRANEL, DANIEL (PI)
  • DAMASIO, ANTONIO (PI)
  • FROMKIN, VICTORIA (PI)
  • VAN HOESEN, GARY (PI)
  • DAMASIO, HANNA (PI)
  • Rizzo, Matthew (PI)
  • TRANEL, DANIEL (PI)
  • FROMKIN, VICTORIA (PI)
  • VAN HOESEN, GARY (PI)
  • Damasio, Hanna C. (PI)
  • Rizzo, Matthew (PI)
  • Rizzo, Matthew (PI)
  • TRANEL, DANIEL (PI)
  • DAMASIO, ANTONIO (PI)
  • DAMASIO, HANNA (PI)
  • VAN HOESEN, GARY (PI)
  • Rizzo, Matthew (PI)
  • TRANEL, DANIEL (PI)
  • VAN HOESEN, GARY (PI)
  • Rizzo, Matthew (PI)
  • Rizzo, Matthew (PI)
  • Adolphs, Ralph (PI)
  • TRANEL, DANIEL (PI)
  • Bechara, Antoine (PI)
  • Adolphs, Ralph (PI)
  • Bechara, Antoine (PI)
  • ANDERSON, STEVEN (PI)
  • VAN HOESEN, GARY (PI)
  • BENTON, ARTHUR (PI)
  • WOOLSON, ROBERT (PI)
  • SPRADLING, JON (PI)
  • DAMASIO, ANTONIO (PI)
  • GRABOWSKI, THOMAS (PI)
  • Bechara, Antoine (PI)
  • ANDERSON, STEVEN (PI)
  • Adolphs, Ralph (PI)
  • TRANEL, DANIEL (PI)
  • DAMASIO, HANNA (PI)
  • DAMASIO, ANTONIO (PI)
  • ANDERSON, STEVEN (PI)
  • Bechara, Antoine (PI)
  • Tranel, Daniel T. (PI)
  • Damasio, Hanna C. (PI)

Project: Research project

Project Details

Description

The study of patients with focal lesions of the central visual system has
shown that certain forms of complex visual disturbance are generally
associated with lesions in the inferior aspect of that system (the inferior
occipital lobe and adjoining temporal lobe), while other disturbances are
more commonly associated with lesions of the superior aspect of that system
(the superior occipital cortices and adjoining parietal lobe). Each of
these systems appears to contain cortical regions specialized in the
processing of salient features such as shape, color, stereopsis and motion,
and in general the dichotomy also relates, respectively to object and
spatial processing. The principal aims of this project are to increase our
knowledge regarding the presumed inferior/superior diversity of human
visual function with respect to a vertical axis about the calcarine
fissure. We also aim to study new aspects of the organization of human
vision beyond the relatively early stages at which processing asymmetries
for basic visual functions are evident. We will test a series of
hypotheses by conducting systematic experiments in a large number of
subjects (newly referred or from the Database/Registry) with damage in
various components of neural systems underlying vision. The anatomical
study is based on a standardized analysis of CT and MR data. The
behavioral study consists of a core of basic neuropsychological tests,
neuro-ophthalmological screening procedures and psychophysical paradigms.
The new experiments are aimed at testing hypotheses on (a) visual search
with eye movements; (b) orienting and sustaining of attention, and the role
of attention in the search for feature conjunctions; (c) reaching and
grasping of external targets; (d) processing of motion, and its combination
with stereopsis to determine the structure of 3-D objects; and (e)
processing of color. The study should contribute to our understanding of
the modular organization of the visual system at a telencephalic level. By
studying vision and its neural substrates revealed in patients with
cognitive impairments due to focal brain lesions, it may be possible to
devise better strategies to diagnose and manage those impairments.
StatusFinished
Effective start/end date1/1/015/31/13

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