Project: Research project

Project Details


Attention deficit hyperactivity disorder (ADHD) is a serious, common,
and chronic behavioral syndrome characterized by impaired attention,
impulsivity, and excessive motor activity. It is a common reason for
service referrals and is a risk factor for multiple poor outcomes. The
proposed study would examine attentional and related inhibitory
processes in the primarily hyperactive/impulsive (ADD+H) and primarily
inattentive (ADD-H) subtypes at two developmental periods. A secondary
goal of the proposed study, intended to increase the breadth of
research, is to explore genetic contributions involved in the etiology
of the two ADHD subtypes. Children will be recruited from local schools
and pediatric clinics. Young adults will be recruited from the
Disabilities Resource Center located on the Michigan State University
Campus and through newspaper ads/fliers distributed in local
communities. ADHD and comorbid diagnoses will be based on parent/
teacher and self report (questionnaires and a structured interview) for
children and adults, respectively, according to DSM-IV criteria.
Participants will complete a computer-generated attentional orienting
task to measure the automatic and effortful allocation of visual
attention and related inhibitory processes. Check cell samples for
genetic analysis will be collected. The proposed cognitive neuroscience
and genetic approach to understanding ADHD has the potential to better
identify the primary cognitive dysfunction in ADHD as well as inform an
etiologic model of these dysfunctions, and thus improve nosology,
leading to the eventual development of better remedial programs.
Effective start/end date4/30/9910/30/01