CANCER AND LEUKEMIA GROUP B

Project: Research project

Project Details

Description

DESCRIPTION (adapted from the applicant's abstract): The purpose of WRAMC
research is the investigation of multi modal treatment and cancer biology in
adult patients with neoplastic diseases in collaboration with other member
institutions in the CALGB. In the past five years protocol accrual had
slowly drifted down from an average of 125/year in the prior five years to
109/year in the last five years with a nadir accrual of 77 in 1995. It
became clear that reorganization and renewed commitment of WRAMC
investigators was essential to our continued success. Multiple
investigators were enlisted to spearhead the WRAMC effort in the different
disease and modality arenas, based on their individual expertise. CALGB
protocol activation rose dramatically from a nadir of 5 in 1995 to 18 in
1996 (260 percent increase). CALGB accrual concomitantly soared from 77 in
1995 to 146 in 1996 (90 percent increase). Attendance at group meetings
rose 76 percent this last five years over the previous similar time period.
Co-Investigators are taking increased leadership roles. Dr. Diehl is the
Study Chair of the next phase III intergroup trial in stage I/II Hodgkin
Disease. Dr. Byrd is chairing the next CALGB phase II/III trial in chronic
lymphocytic leukemia. Furthermore, calling on military alliances, WRAMC
added its first two affiliates, the National Naval Medical Center in
Bethesda, Maryland and the Naval Medical Center in Portsmouth, Virginia, two
of the top three Navy Medical Centers. These affiliations will not only
increase accrual to CALGB studies, but compliment WRAMC's expertise by
adding cutting-edge cancer research in colon, lung and breast cancer, in
particular, as well as providing the oncologic care for the Navy and the
NCI, opens a tremendous potential avenue for extramural-intramural
scientific collaboration. The commitment by the Molecular Pathology Branch
of the AFIP to serve as a designated laboratory for the next CLL correlative
science study further expands WRAMC's potential group contributions. As
WRAMC expands its clinical research program, it is critical that it
continues to emphasize quality data management, which in 1996 was labeled
"excellent". As accrual is expected to steadily increase, due to new
affiliates and increased investigator involvement, enhanced support for
additional clinical research associates becomes essential to success.
StatusFinished
Effective start/end date4/1/013/31/02

Funding

  • National Cancer Institute: $23,247.00

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