Effects of Partner Violence and Mental Health on HIV Disease Progression in Women

Project: Research project

Description

DESCRIPTION (provided by applicant): The proposed mixed-methods study aims to examine the complex relationship between intimate partner violence (IPV) and reproductive coercion, mental health and HIV treatment adherence and disease progression. Pathways including substance abuse, depression and post-traumatic stress disorder will be examined. Women will be recruited from an urban HIV clinic that serves a primarily low income, African American population. African American women are disproportionally affected by the intertwined epidemics of HIV, violence and substance abuse. Phase 1 of the study will include quantitative data regarding past year, IPV, reproductive coercion, PTSD symptoms, depressive symptoms, substance abuse, and HIV medication adherence collected from eligible women. Participant's medical records will be reviewed to obtain biologic markers of disease progression and medication adherence (CD4 count and viral load) as well as covariates related to HIV disease progression (hospitalizations, opportunistic infections) and verification of mental health related diagnoses (PTSD, depression, substance abuse). Prevalence of IPV and reproductive coercion will be estimated, prior to examining the direct and mediated effects of IPV and reproductive coercion on HIV disease progression and treatment adherence (CD4 counts, viral load and missed clinic visits). Following analysis of Phase 1 data, a subsample of women will be purposefully selected for Phase 2 qualitative interviews. The aim of these qualitative interviews is to explore women's perceptions on IPV and reproductive coercion and the role in adherence and disease progression. The findings from the proposed study will be used to inform culturally competent interventions to reduce health disparities among urban, HIV positive women.
StatusFinished
Effective start/end date9/1/138/31/16

Funding

  • National Institutes of Health: $42,676.00
  • National Institutes of Health: $42,822.00
  • National Institutes of Health: $42,232.00

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Violence
Coercion
Disease Progression
Mental Health
HIV
Substance-Related Disorders
Post-Traumatic Stress Disorders
Medication Adherence
Depression
CD4 Lymphocyte Count
Viral Load
African Americans
Interviews
Opportunistic Infections
Ambulatory Care
Medical Records
Hospitalization
Biomarkers
Intimate Partner Violence
Health