Emotion regulation of children exposed to cocaine

Project: Research project

Project Details


DESCRIPTION: (provided by applicant)
Previous research with children prenatally exposed to cocaine has suggested a
relation between prenatal cocaine exposure and children's emotion regulation
and affect before age 2 years. This study will compare the impacts of
contextual risk, maternal psychiatric status, and maternal prenatal, postnatal,
and current cocaine use on children's emotion regulation and negative and
positive affect at age 9 years. Child gender will be used as a moderator.
Further, the ability of children's emotion regulation and negative and positive
affect to mediate the relations between the predictors of contextual risk,
mother's psychiatric status, mother's cocaine use, and the outcomes of
children's attention, behavior and language development will be explored. This
study is a secondary data analysis of ongoing research examining the impact of
prenatal cocaine exposure on children's cognitive, behavioral, and attentional
development. Additionally, emotion regulation and affect data will be coded
using previously recorded videotapes and will provide the central variable for
these analyses. The data set to be analyzed includes data collected from
prenatally exposed 9-year-old children and their biological mothers (n=60), and
from a retrospectively recruited contrast group (n=60). Maternal cocaine use
for the prenatally exposed group was determined using hair and urine samples at
child's delivery, at infant ages 4, 8, 12, 16, 20, and 24 months, and again
from hair samples when the children were 9 years of age. Maternal cocaine use
for the contrast group was determined using maternal self-report of prenatal
and postnatal use, and from hair samples when the children were 9 years of age.
A single contextual risk variable will be calculated, based on the work of
Sameroff (1993), using the following risks: maternal occupation a I or 2 on the
Hollingshead index; mother not a high school graduate; four or more children
living in the home; no father figure in the home; high financial stress;
stressful life events; negative neighborhood events; maternal endorsement of
harsh parenting. Principal components analysis of the scores on the Millon
Clinical Multiaxial Inventory II (MCMI-11) scales most often associated with
substance use will be combined to form a single psychiatric risk score.
Children's attention will be measured using the Conners' Teacher Rating Scales;
behavior, using the Child Behavior Checklist (CBCL); and language, using the
Clinical Evaluation of Language Functioning (CELF). Analyses will include
stepwise and hierarchical regressions and a mediational analysis. Results from
this study will be disseminated via conferences and though submission of a
manuscript to a peer-reviewed journal, and will also be used as pilot data for
an R01 submission by the principal investigator.
Effective start/end date4/1/029/30/03


  • National Institute on Drug Abuse: $75,385.00


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