Project Narrative The proposed work focuses on the design and synthesis of fluoroalkyl group-carrying analogs of S- adenosylmethionine, and their use in performing regio- and stereoselective enzymatic fluoroalkylation. The work provides a novel approach for late stage fluoroalkylation, which enables facile derivatization of a wide range of antibacterial natural products.
|Effective start/end date||3/15/21 → 2/28/23|
- National Institute of Allergy and Infectious Diseases: $189,000.00
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