IMAGING ALZHEIMER'S PATIENTS VS. CONTROLS

Project: Research project

Description

The purpose of this study is to determine whether the magnetic resonance
image will differentiate healthy brain from those with Alzheimer's
Disease. The study will compare brain images from 15 patients diagnosed as
Dementia Alzheimer's Type (DSM III) and Probable Alzheimer's to those of a
group of age and sex matched healthy controls. The brain slices to be
imaged will allow examination of portions of gray and white matter in
samples of the frontal, posterior-frontal/anterior-parietal, parietal,
temporal and occipital lobes, as well as the caudate and thalamus. The
coronal slice will allow examination of the diencephalic structures and the
temporal lobe. A second objective is to determine which slices are the
most useful in detecting differences between the two groups. In addition,
the images for the control subjects will be compared to a group of younger
healthy controls (subjects in a schizophrenic study at this Institute) to
detect differences attributable to normal imaging.
StatusActive
Effective start/end date8/1/85 → …

Funding

  • National Institutes of Health
  • National Institutes of Health: $28,600.00

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Lipid Metabolism
Brain
Occipital Lobe
Parietal Lobe
Temporal Lobe
Thalamus
Diagnostic and Statistical Manual of Mental Disorders
Control Groups