Poly-omic predictors of symptom duration and recovery for adolescent concussion

Project: Research project

Project Details


PROJECT NARRATIVE Mild traumatic brain injury is extremely common among adolescents, who suffer disproportionately from prolonged concussion symptoms – a condition for which no biologic test exists. Emerging evidence suggests non-coding RNA released into saliva by neurons and glia, may provide a biologic window into the brain’s repair response. This study will measure longitudinal brain-related RNA levels in the saliva of adolescents with mild traumatic brain injury to: 1) validate an innovative method that helps clinicians predict the duration and character of concussion symptoms; and 2) define a biologic signature that aids assessment of concussion recovery for return-to-play and return-to-learn decisions.
Effective start/end date1/1/2012/31/22


  • National Institute of Neurological Disorders and Stroke: $609,107.00


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