Targeting trans-translation to kill M. tuberculosis non-replicating persister cells

Project: Research project

Project Details

Description

NARRATIVE
Drug-resistant strains of Mycobacterium tuberculosis present a critical challenge to world health, and new
antibiotic targets must be identified to limit the toll of tuberculosis. This project will establish whether trans-
translation can be targeted in M. tuberculosis and test the efficacy of lead compounds in vivo. New antibiotics
are expected to be developed from the results of the proposed experiments.
StatusActive
Effective start/end date11/1/2110/31/22

Funding

  • National Institute of Allergy and Infectious Diseases: $691,652.00

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