PROJECT NARRATIVE In this project, we propose to study DNA sequences capable of forming non-canonical DNA conformations called G-quadruplexes. G-quadruplex formation is associated with several diseases, including Amyotrophic Lateral Sclerosis and cancer. Studying G-quadruplexes will advance our understanding of their role in disease etiology and will inform the development of personalized disease treatments.
|Effective start/end date||1/1/21 → 12/31/22|
- National Institute of General Medical Sciences: $511,085.00
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