The impact of G-quadruplexes on genome evolution

Project: Research project

Project Details

Description

PROJECT NARRATIVE In this project, we propose to study DNA sequences capable of forming non-canonical DNA conformations called G-quadruplexes. G-quadruplex formation is associated with several diseases, including Amyotrophic Lateral Sclerosis and cancer. Studying G-quadruplexes will advance our understanding of their role in disease etiology and will inform the development of personalized disease treatments.
StatusActive
Effective start/end date1/1/2112/31/22

Funding

  • National Institute of General Medical Sciences: $511,085.00

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