Training Program in Trauma and Organ Injury

  • Lang, Charles (PI)
  • Cooney, Robert (PI)

Project: Research project

Project Details


DESCRIPTION (provided by applicant): Traumatic injury continues to be a major
public health problem that impacts enormously on individuals and society. An
essential component of the trauma health care system is basic and clinical
research. However, future advancements in trauma research are likely to be
hindered because of the continued decline in the number of well-trained
physician-scientists. The proposed Training Program in Trauma and Organ Injury
is designed primarily for surgical residents to provide them with an intensive
two-year period of research training focused on the mechanisms responsible for
the cellular dysfunction and multiorgan failure associated with injury. It will
complement the ongoing trauma research programs already present in the
Departments of Surgery, and Cellular and Molecular Physiology. The goal of the
training program is to provide highly qualified, motivated individuals with an
in-depth knowledge base and intensive laboratory experience that will
facilitate successful, productive careers in independent academic trauma
research. The specific aims of the training program are to: (1) provide
comprehensive scientific training focused in one of three major disciplines;
Endocrinology/Metabolism, Organ Injury and Tissue Repair, or Neurobiology; and
(2) provide a strong training foundation in all aspects of the investigative
process. The training objectives will emphasize integrating physiology,
biochemistry, endocrinology, and neurobiology with techniques of cellular and
molecular biology. Established investigators (both clinical and basic
scientists) within the Departments of Surgery, Cellular and Molecular
Physiology, Orthopedics, Internal Medicine/Cardiology, Pediatrics, and
Neuroscience and Anatomy will serve as core faculty mentors, and will be
responsible for directing and evaluating the trainee's progress. Trainees will
receive direct supervision regarding all aspects of experimental design,
technical expertise, and scientific writing as well as participate in the
required course on ethical conduct in research. Candidates will be recruited
both locally and nationally, and extensive efforts will be made to recruit
women and minority candidates into the program. Program graduates will be
clinician-scientists who possess sufficient scientific maturity to embark on a
career in independent research and make significant contributions to the
advancement of knowledge concerning the pathophysiology of trauma.
Effective start/end date7/1/026/30/12


  • National Institute of General Medical Sciences: $110,948.00
  • National Institute of General Medical Sciences: $115,484.00


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