β-adrenergic involvement in classical conditioning and extinction was investigated. Five groups of rabbits (saline, 1, 3, 5 or 10 mg kg-1 of the β-adrenergic antagonist propranolol) were trained with a tone conditioned stimulus (CS) paired with a corneal air puff unconditioned stimulus (US). Both 5 mg kg-1 and 10 mg kg-1 propranolol delayed acquisition of conditioned responses but all groups were able to learn the task to criterion. Consistent changes were not seen during extinction.
All Science Journal Classification (ASJC) codes
- Molecular Biology
- Clinical Neurology
- Developmental Biology