β-adrenergic involvement in acquisition vs. extinction of a classically conditioned eye blink response in rabbits

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Abstract

β-adrenergic involvement in classical conditioning and extinction was investigated. Five groups of rabbits (saline, 1, 3, 5 or 10 mg kg-1 of the β-adrenergic antagonist propranolol) were trained with a tone conditioned stimulus (CS) paired with a corneal air puff unconditioned stimulus (US). Both 5 mg kg-1 and 10 mg kg-1 propranolol delayed acquisition of conditioned responses but all groups were able to learn the task to criterion. Consistent changes were not seen during extinction.

Original languageEnglish (US)
Pages (from-to)174-177
Number of pages4
JournalBrain research
Volume780
Issue number1
DOIs
StatePublished - Jan 5 1998

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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