β-carotene uptake from processed versus raw vegetables in women

J. L. Lovalvo, C. L. Rock, Mack Ruffin, C. Emenhiser, W. Disario, S. J. Schwartz

Research output: Contribution to journalArticle

Abstract

Bioavailability of β-carotene is known to be influenced by several dietary factors and characteristics of the food matrix. Tissue uptake from food sources is relevant to both cancer chemoprevention and the eradication of vitamin A inadequacy in undernourished populations. The purpose of this study was to examine the uptake of β-carotene and its isomers from processed versus raw carotenoid-rich vegetables (carrots, spinach). Eight healthy adult females (ages 17-36) participated in the crossover study, comprised of two 4-week treatment periods, in which they were fed approximately 9277 μg β-carotene per day from either processed or raw sources. The amount of β-carotene provided by the food was determined by HPLC methods. Plasma carotenoids, including their isomeric distributions, were measured at baseline and at the end of each treatment period using HPLC. Total plasma βcarotene increased significantly following the processed vegetable feeding period (P = 0.04), and tended to increase following the raw vegetable feeding period (P = 0.07). Average total plasma β-carotene increased by 102% and 33% following the processed and raw feeding periods, respectively. In selected subjects, cervix tissue uptake of β-carotene was also examined in the processed feeding period and a similar average magnitude of increase was observed. Results from this study indicate that daily consumption of carotenoid-rich vegetables, particularly when processed, results in a nromnt and substantial increase in tissue β-carotene concentration.

Original languageEnglish (US)
JournalFASEB Journal
Volume10
Issue number3
StatePublished - Dec 1 1996

Fingerprint

raw vegetables
Vegetables
Carotenoids
carotenes
uptake mechanisms
carotenoids
vegetables
Tissue
Plasmas
Food
chemoprevention
cervix
food matrix
High Pressure Liquid Chromatography
spinach
carrots
vitamin A
isomers
Daucus carota
bioavailability

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biochemistry
  • Molecular Biology
  • Genetics

Cite this

Lovalvo, J. L., Rock, C. L., Ruffin, M., Emenhiser, C., Disario, W., & Schwartz, S. J. (1996). β-carotene uptake from processed versus raw vegetables in women. FASEB Journal, 10(3).
Lovalvo, J. L. ; Rock, C. L. ; Ruffin, Mack ; Emenhiser, C. ; Disario, W. ; Schwartz, S. J. / β-carotene uptake from processed versus raw vegetables in women. In: FASEB Journal. 1996 ; Vol. 10, No. 3.
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Lovalvo, JL, Rock, CL, Ruffin, M, Emenhiser, C, Disario, W & Schwartz, SJ 1996, 'β-carotene uptake from processed versus raw vegetables in women', FASEB Journal, vol. 10, no. 3.

β-carotene uptake from processed versus raw vegetables in women. / Lovalvo, J. L.; Rock, C. L.; Ruffin, Mack; Emenhiser, C.; Disario, W.; Schwartz, S. J.

In: FASEB Journal, Vol. 10, No. 3, 01.12.1996.

Research output: Contribution to journalArticle

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AU - Lovalvo, J. L.

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AU - Schwartz, S. J.

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Lovalvo JL, Rock CL, Ruffin M, Emenhiser C, Disario W, Schwartz SJ. β-carotene uptake from processed versus raw vegetables in women. FASEB Journal. 1996 Dec 1;10(3).