β-Trimethylsilylethanesulfonyl chloride (SES-Cl): A new reagent for protection of amines

Steven M. Weinreb, Donald M. Demko, Thomas A. Lessen, James P. Demers

Research output: Contribution to journalArticle

160 Scopus citations

Abstract

The title compound, easily prepared in two steps from vinyltrimethylsilane, is a useful reagent for the protection of primary and secondary amines as their sulfonamides, which are cleaved by fluoride ion.

Original languageEnglish (US)
Pages (from-to)2099-2102
Number of pages4
JournalTetrahedron Letters
Volume27
Issue number19
DOIs
StatePublished - 1986

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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