TY - JOUR
T1 - 1-[(1S,2S)-1,2-Bis(2-hydroxyphenyl)-2- pivaloylaminoethylamino]-2,2-dimethyl-1-propanone
AU - Lugemwa, Fulgentius Nelson
N1 - Funding Information:
Funding: Funds from †he Pennsylvania State University-York Advisory Board Grant and Smith Funds were used for this work.
Publisher Copyright:
© 2019 by the authors. Licensee MDPI, Basel, Switzerland.
Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2019/3
Y1 - 2019/3
N2 - When 2-[(1S,2S)-1,2-diamino-2(2-hydroxyphenyl)ethyl]phenol (I) was reacted with 2 mole equivalents of trimethyl acetic (pivalic) anhydride in tetrahydrofuran at room temperature, 1-[(1S,2S)-1,2-bis(2-hydroxyphenyl)-2-pivaloylaminoethylamino]-2,2-dimethyl-1-propanone (II) was obtained quantitatively as the only product. The structure of the product was determined using 1 Hand 13 C-NMR. The COSY spectrum indicated that the single -NH was coupled to the single benzylic proton, -CH. The versality of the transformation could be used to generate additional compounds for use in various research areas.
AB - When 2-[(1S,2S)-1,2-diamino-2(2-hydroxyphenyl)ethyl]phenol (I) was reacted with 2 mole equivalents of trimethyl acetic (pivalic) anhydride in tetrahydrofuran at room temperature, 1-[(1S,2S)-1,2-bis(2-hydroxyphenyl)-2-pivaloylaminoethylamino]-2,2-dimethyl-1-propanone (II) was obtained quantitatively as the only product. The structure of the product was determined using 1 Hand 13 C-NMR. The COSY spectrum indicated that the single -NH was coupled to the single benzylic proton, -CH. The versality of the transformation could be used to generate additional compounds for use in various research areas.
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U2 - 10.3390/M1054
DO - 10.3390/M1054
M3 - Article
AN - SCOPUS:85064441573
VL - 2019
JO - MolBank
JF - MolBank
SN - 1422-8599
IS - 1
M1 - M1054
ER -