Abstract
When 2-[(1S,2S)-1,2-diamino-2(2-hydroxyphenyl)ethyl]phenol (I) was reacted with 2 mole equivalents of trimethyl acetic (pivalic) anhydride in tetrahydrofuran at room temperature, 1-[(1S,2S)-1,2-bis(2-hydroxyphenyl)-2-pivaloylaminoethylamino]-2,2-dimethyl-1-propanone (II) was obtained quantitatively as the only product. The structure of the product was determined using 1 Hand 13 C-NMR. The COSY spectrum indicated that the single -NH was coupled to the single benzylic proton, -CH. The versality of the transformation could be used to generate additional compounds for use in various research areas.
| Original language | English (US) |
|---|---|
| Article number | M1054 |
| Journal | MolBank |
| Volume | 2019 |
| Issue number | 1 |
| DOIs | |
| State | Published - Mar 1 2019 |
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All Science Journal Classification (ASJC) codes
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
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1-[(1S,2S)-1,2-Bis(2-hydroxyphenyl)-2- pivaloylaminoethylamino]-2,2-dimethyl-1-propanone. / Lugemwa, Fulgentius Nelson.
In: MolBank, Vol. 2019, No. 1, M1054, 01.03.2019.Research output: Contribution to journal › Article
TY - JOUR
T1 - 1-[(1S,2S)-1,2-Bis(2-hydroxyphenyl)-2- pivaloylaminoethylamino]-2,2-dimethyl-1-propanone
AU - Lugemwa, Fulgentius Nelson
PY - 2019/3/1
Y1 - 2019/3/1
N2 - When 2-[(1S,2S)-1,2-diamino-2(2-hydroxyphenyl)ethyl]phenol (I) was reacted with 2 mole equivalents of trimethyl acetic (pivalic) anhydride in tetrahydrofuran at room temperature, 1-[(1S,2S)-1,2-bis(2-hydroxyphenyl)-2-pivaloylaminoethylamino]-2,2-dimethyl-1-propanone (II) was obtained quantitatively as the only product. The structure of the product was determined using 1 Hand 13 C-NMR. The COSY spectrum indicated that the single -NH was coupled to the single benzylic proton, -CH. The versality of the transformation could be used to generate additional compounds for use in various research areas.
AB - When 2-[(1S,2S)-1,2-diamino-2(2-hydroxyphenyl)ethyl]phenol (I) was reacted with 2 mole equivalents of trimethyl acetic (pivalic) anhydride in tetrahydrofuran at room temperature, 1-[(1S,2S)-1,2-bis(2-hydroxyphenyl)-2-pivaloylaminoethylamino]-2,2-dimethyl-1-propanone (II) was obtained quantitatively as the only product. The structure of the product was determined using 1 Hand 13 C-NMR. The COSY spectrum indicated that the single -NH was coupled to the single benzylic proton, -CH. The versality of the transformation could be used to generate additional compounds for use in various research areas.
UR - http://www.scopus.com/inward/record.url?scp=85064441573&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85064441573&partnerID=8YFLogxK
U2 - 10.3390/M1054
DO - 10.3390/M1054
M3 - Article
VL - 2019
JO - MolBank
JF - MolBank
SN - 1422-8599
IS - 1
M1 - M1054
ER -