2,3,7,8-Tetrachlorodibenzo-p-dioxin Levels in Adipose Tissue of Exposed and Control Persons in Missouri: An Interim Report

Donald George Jr Patterson, Richard E. Hoffman, Larry L. Needham, Daryl W. Roberts, John R. Bagby, James L. Pirkle, Henry Falk, Eric J. Sampson, Vernon N. Houk

Research output: Contribution to journalArticle

84 Citations (Scopus)

Abstract

The compound 2,3,7,8-tetrachlorodibenzo-p-dioxin, commonly known as dioxin, was measured in the adipose tissue of 39 persons with a history of residential, recreational, or occupational exposure in Missouri and in 57 persons in a control group. All participants had detectable levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin in their adipose tissue, but the exposed group had significantly higher levels. Levels of six of the exposed persons were more than five times greater than the level of the highest control. Measuring 2,3,7,8-tetrachlorodibenzo-p-dioxin in adipose tissue provides a much improved index of exposure, an important advance for research studies evaluating the possible health effects of this compound.

Original languageEnglish (US)
Pages (from-to)2683-2686
Number of pages4
JournalJAMA: The Journal of the American Medical Association
Volume256
Issue number19
DOIs
StatePublished - Nov 21 1986

Fingerprint

Adipose Tissue
Dioxins
Occupational Exposure
Control Groups
Health
Research
Polychlorinated Dibenzodioxins

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Patterson, Donald George Jr ; Hoffman, Richard E. ; Needham, Larry L. ; Roberts, Daryl W. ; Bagby, John R. ; Pirkle, James L. ; Falk, Henry ; Sampson, Eric J. ; Houk, Vernon N. / 2,3,7,8-Tetrachlorodibenzo-p-dioxin Levels in Adipose Tissue of Exposed and Control Persons in Missouri : An Interim Report. In: JAMA: The Journal of the American Medical Association. 1986 ; Vol. 256, No. 19. pp. 2683-2686.
@article{4fa7f7dffa6a4753a7a7eed8d5e88e50,
title = "2,3,7,8-Tetrachlorodibenzo-p-dioxin Levels in Adipose Tissue of Exposed and Control Persons in Missouri: An Interim Report",
abstract = "The compound 2,3,7,8-tetrachlorodibenzo-p-dioxin, commonly known as dioxin, was measured in the adipose tissue of 39 persons with a history of residential, recreational, or occupational exposure in Missouri and in 57 persons in a control group. All participants had detectable levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin in their adipose tissue, but the exposed group had significantly higher levels. Levels of six of the exposed persons were more than five times greater than the level of the highest control. Measuring 2,3,7,8-tetrachlorodibenzo-p-dioxin in adipose tissue provides a much improved index of exposure, an important advance for research studies evaluating the possible health effects of this compound.",
author = "Patterson, {Donald George Jr} and Hoffman, {Richard E.} and Needham, {Larry L.} and Roberts, {Daryl W.} and Bagby, {John R.} and Pirkle, {James L.} and Henry Falk and Sampson, {Eric J.} and Houk, {Vernon N.}",
year = "1986",
month = "11",
day = "21",
doi = "10.1001/jama.1986.03380190053024",
language = "English (US)",
volume = "256",
pages = "2683--2686",
journal = "JAMA - Journal of the American Medical Association",
issn = "0002-9955",
publisher = "American Medical Association",
number = "19",

}

Patterson, DGJ, Hoffman, RE, Needham, LL, Roberts, DW, Bagby, JR, Pirkle, JL, Falk, H, Sampson, EJ & Houk, VN 1986, '2,3,7,8-Tetrachlorodibenzo-p-dioxin Levels in Adipose Tissue of Exposed and Control Persons in Missouri: An Interim Report', JAMA: The Journal of the American Medical Association, vol. 256, no. 19, pp. 2683-2686. https://doi.org/10.1001/jama.1986.03380190053024

2,3,7,8-Tetrachlorodibenzo-p-dioxin Levels in Adipose Tissue of Exposed and Control Persons in Missouri : An Interim Report. / Patterson, Donald George Jr; Hoffman, Richard E.; Needham, Larry L.; Roberts, Daryl W.; Bagby, John R.; Pirkle, James L.; Falk, Henry; Sampson, Eric J.; Houk, Vernon N.

In: JAMA: The Journal of the American Medical Association, Vol. 256, No. 19, 21.11.1986, p. 2683-2686.

Research output: Contribution to journalArticle

TY - JOUR

T1 - 2,3,7,8-Tetrachlorodibenzo-p-dioxin Levels in Adipose Tissue of Exposed and Control Persons in Missouri

T2 - An Interim Report

AU - Patterson, Donald George Jr

AU - Hoffman, Richard E.

AU - Needham, Larry L.

AU - Roberts, Daryl W.

AU - Bagby, John R.

AU - Pirkle, James L.

AU - Falk, Henry

AU - Sampson, Eric J.

AU - Houk, Vernon N.

PY - 1986/11/21

Y1 - 1986/11/21

N2 - The compound 2,3,7,8-tetrachlorodibenzo-p-dioxin, commonly known as dioxin, was measured in the adipose tissue of 39 persons with a history of residential, recreational, or occupational exposure in Missouri and in 57 persons in a control group. All participants had detectable levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin in their adipose tissue, but the exposed group had significantly higher levels. Levels of six of the exposed persons were more than five times greater than the level of the highest control. Measuring 2,3,7,8-tetrachlorodibenzo-p-dioxin in adipose tissue provides a much improved index of exposure, an important advance for research studies evaluating the possible health effects of this compound.

AB - The compound 2,3,7,8-tetrachlorodibenzo-p-dioxin, commonly known as dioxin, was measured in the adipose tissue of 39 persons with a history of residential, recreational, or occupational exposure in Missouri and in 57 persons in a control group. All participants had detectable levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin in their adipose tissue, but the exposed group had significantly higher levels. Levels of six of the exposed persons were more than five times greater than the level of the highest control. Measuring 2,3,7,8-tetrachlorodibenzo-p-dioxin in adipose tissue provides a much improved index of exposure, an important advance for research studies evaluating the possible health effects of this compound.

UR - http://www.scopus.com/inward/record.url?scp=84944282890&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84944282890&partnerID=8YFLogxK

U2 - 10.1001/jama.1986.03380190053024

DO - 10.1001/jama.1986.03380190053024

M3 - Article

AN - SCOPUS:84944282890

VL - 256

SP - 2683

EP - 2686

JO - JAMA - Journal of the American Medical Association

JF - JAMA - Journal of the American Medical Association

SN - 0002-9955

IS - 19

ER -