2,3,7,8-Tetrachlorodibenzo-p-dioxin levels in adipose tissue of exposed and control persons in Missouri. An interim report

Donald George Jr Patterson, R. E. Hoffman, L. L. Needham, D. W. Roberts, J. R. Bagby, J. L. Pirkle, H. Falk, E. J. Sampson, V. N. Houk

Research output: Contribution to journalArticle

Abstract

The compound 2,3,7,8-tetrachlorodibenzo-p-dioxin, commonly known as dioxin, was measured in the adipose tissue of 39 persons with a history of residential, recreational, or occupational exposure in Missouri and in 57 persons in a control group. All participants had detectable levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin in their adipose tissue, but the exposed group had significantly higher levels. Levels of six of the exposed persons were more than five times greater than the level of the highest control. Measuring 2,3,7,8-tetrachlorodibenzo-p-dioxin in adipose tissue provides a much improved index of exposure, an important advance for research studies evaluating the possible health effects of this compound.

Original languageEnglish (US)
Pages (from-to)2683-2686
Number of pages4
JournalJournal of the American Medical Association
Volume256
Issue number19
DOIs
StatePublished - Dec 1 1986

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Adipose Tissue
Dioxins
Occupational Exposure
Control Groups
Health
Research
Polychlorinated Dibenzodioxins

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Patterson, D. G. J., Hoffman, R. E., Needham, L. L., Roberts, D. W., Bagby, J. R., Pirkle, J. L., ... Houk, V. N. (1986). 2,3,7,8-Tetrachlorodibenzo-p-dioxin levels in adipose tissue of exposed and control persons in Missouri. An interim report. Journal of the American Medical Association, 256(19), 2683-2686. https://doi.org/10.1001/jama.256.19.2683
Patterson, Donald George Jr ; Hoffman, R. E. ; Needham, L. L. ; Roberts, D. W. ; Bagby, J. R. ; Pirkle, J. L. ; Falk, H. ; Sampson, E. J. ; Houk, V. N. / 2,3,7,8-Tetrachlorodibenzo-p-dioxin levels in adipose tissue of exposed and control persons in Missouri. An interim report. In: Journal of the American Medical Association. 1986 ; Vol. 256, No. 19. pp. 2683-2686.
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Patterson, DGJ, Hoffman, RE, Needham, LL, Roberts, DW, Bagby, JR, Pirkle, JL, Falk, H, Sampson, EJ & Houk, VN 1986, '2,3,7,8-Tetrachlorodibenzo-p-dioxin levels in adipose tissue of exposed and control persons in Missouri. An interim report', Journal of the American Medical Association, vol. 256, no. 19, pp. 2683-2686. https://doi.org/10.1001/jama.256.19.2683

2,3,7,8-Tetrachlorodibenzo-p-dioxin levels in adipose tissue of exposed and control persons in Missouri. An interim report. / Patterson, Donald George Jr; Hoffman, R. E.; Needham, L. L.; Roberts, D. W.; Bagby, J. R.; Pirkle, J. L.; Falk, H.; Sampson, E. J.; Houk, V. N.

In: Journal of the American Medical Association, Vol. 256, No. 19, 01.12.1986, p. 2683-2686.

Research output: Contribution to journalArticle

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