3D Printing Artificial Blood Vessel Constructs Using PCL/Chitosan/Hydrogel Biocomposites

Songul Ulag, Cevriye Kalkandelen, Faik Nuzhet Oktar, Muhammet Uzun, Yesim Muge Sahin, Betul Karademir, Sema Arslan, Ibrahim Tarik Ozbolat, Mahir Mahirogullari, Oguzhan Gunduz

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

The present paper aims to overcome the problems related to previous use of autologous grafts using available synthetic grafts. To examine the optimum of the ideal vessel-like constructs parameters are produced at 230 °C. At this production temperature, the elastic modulus values of the constructs ranges from 56 MPa to 174 MPa. The maximum cell proliferation is obtained from PCL/7wt.%CS/5wt.%H that is tested by mitochondrial dehydrogenase activity. The structures are visualized with all constructs after cell fixation by making use of the HUVEC cell line.

Original languageEnglish (US)
Pages (from-to)2387-2391
Number of pages5
JournalChemistrySelect
Volume4
Issue number8
DOIs
StatePublished - Feb 28 2019

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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