3D Printing Artificial Blood Vessel Constructs Using PCL/Chitosan/Hydrogel Biocomposites

Songul Ulag, Cevriye Kalkandelen, Faik Nuzhet Oktar, Muhammet Uzun, Yesim Muge Sahin, Betul Karademir, Sema Arslan, Ibrahim Tarik Ozbolat, Mahir Mahirogullari, Oguzhan Gunduz

Research output: Contribution to journalArticle

Abstract

The present paper aims to overcome the problems related to previous use of autologous grafts using available synthetic grafts. To examine the optimum of the ideal vessel-like constructs parameters are produced at 230 °C. At this production temperature, the elastic modulus values of the constructs ranges from 56 MPa to 174 MPa. The maximum cell proliferation is obtained from PCL/7wt.%CS/5wt.%H that is tested by mitochondrial dehydrogenase activity. The structures are visualized with all constructs after cell fixation by making use of the HUVEC cell line.

Original languageEnglish (US)
Pages (from-to)2387-2391
Number of pages5
JournalChemistrySelect
Volume4
Issue number8
DOIs
StatePublished - Feb 28 2019

Fingerprint

Blood vessel prostheses
Hydrogel
Chitosan
Grafts
Printing
Cell proliferation
Oxidoreductases
Elastic moduli
Cells
Temperature

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

Cite this

Ulag, S., Kalkandelen, C., Oktar, F. N., Uzun, M., Sahin, Y. M., Karademir, B., ... Gunduz, O. (2019). 3D Printing Artificial Blood Vessel Constructs Using PCL/Chitosan/Hydrogel Biocomposites. ChemistrySelect, 4(8), 2387-2391. https://doi.org/10.1002/slct.201803740
Ulag, Songul ; Kalkandelen, Cevriye ; Oktar, Faik Nuzhet ; Uzun, Muhammet ; Sahin, Yesim Muge ; Karademir, Betul ; Arslan, Sema ; Ozbolat, Ibrahim Tarik ; Mahirogullari, Mahir ; Gunduz, Oguzhan. / 3D Printing Artificial Blood Vessel Constructs Using PCL/Chitosan/Hydrogel Biocomposites. In: ChemistrySelect. 2019 ; Vol. 4, No. 8. pp. 2387-2391.
@article{776c40f528604eb4a44b0e4b6a6bf670,
title = "3D Printing Artificial Blood Vessel Constructs Using PCL/Chitosan/Hydrogel Biocomposites",
abstract = "The present paper aims to overcome the problems related to previous use of autologous grafts using available synthetic grafts. To examine the optimum of the ideal vessel-like constructs parameters are produced at 230 °C. At this production temperature, the elastic modulus values of the constructs ranges from 56 MPa to 174 MPa. The maximum cell proliferation is obtained from PCL/7wt.{\%}CS/5wt.{\%}H that is tested by mitochondrial dehydrogenase activity. The structures are visualized with all constructs after cell fixation by making use of the HUVEC cell line.",
author = "Songul Ulag and Cevriye Kalkandelen and Oktar, {Faik Nuzhet} and Muhammet Uzun and Sahin, {Yesim Muge} and Betul Karademir and Sema Arslan and Ozbolat, {Ibrahim Tarik} and Mahir Mahirogullari and Oguzhan Gunduz",
year = "2019",
month = "2",
day = "28",
doi = "10.1002/slct.201803740",
language = "English (US)",
volume = "4",
pages = "2387--2391",
journal = "ChemistrySelect",
issn = "2365-6549",
publisher = "Wiley-Blackwell Publishing Ltd",
number = "8",

}

Ulag, S, Kalkandelen, C, Oktar, FN, Uzun, M, Sahin, YM, Karademir, B, Arslan, S, Ozbolat, IT, Mahirogullari, M & Gunduz, O 2019, '3D Printing Artificial Blood Vessel Constructs Using PCL/Chitosan/Hydrogel Biocomposites', ChemistrySelect, vol. 4, no. 8, pp. 2387-2391. https://doi.org/10.1002/slct.201803740

3D Printing Artificial Blood Vessel Constructs Using PCL/Chitosan/Hydrogel Biocomposites. / Ulag, Songul; Kalkandelen, Cevriye; Oktar, Faik Nuzhet; Uzun, Muhammet; Sahin, Yesim Muge; Karademir, Betul; Arslan, Sema; Ozbolat, Ibrahim Tarik; Mahirogullari, Mahir; Gunduz, Oguzhan.

In: ChemistrySelect, Vol. 4, No. 8, 28.02.2019, p. 2387-2391.

Research output: Contribution to journalArticle

TY - JOUR

T1 - 3D Printing Artificial Blood Vessel Constructs Using PCL/Chitosan/Hydrogel Biocomposites

AU - Ulag, Songul

AU - Kalkandelen, Cevriye

AU - Oktar, Faik Nuzhet

AU - Uzun, Muhammet

AU - Sahin, Yesim Muge

AU - Karademir, Betul

AU - Arslan, Sema

AU - Ozbolat, Ibrahim Tarik

AU - Mahirogullari, Mahir

AU - Gunduz, Oguzhan

PY - 2019/2/28

Y1 - 2019/2/28

N2 - The present paper aims to overcome the problems related to previous use of autologous grafts using available synthetic grafts. To examine the optimum of the ideal vessel-like constructs parameters are produced at 230 °C. At this production temperature, the elastic modulus values of the constructs ranges from 56 MPa to 174 MPa. The maximum cell proliferation is obtained from PCL/7wt.%CS/5wt.%H that is tested by mitochondrial dehydrogenase activity. The structures are visualized with all constructs after cell fixation by making use of the HUVEC cell line.

AB - The present paper aims to overcome the problems related to previous use of autologous grafts using available synthetic grafts. To examine the optimum of the ideal vessel-like constructs parameters are produced at 230 °C. At this production temperature, the elastic modulus values of the constructs ranges from 56 MPa to 174 MPa. The maximum cell proliferation is obtained from PCL/7wt.%CS/5wt.%H that is tested by mitochondrial dehydrogenase activity. The structures are visualized with all constructs after cell fixation by making use of the HUVEC cell line.

UR - http://www.scopus.com/inward/record.url?scp=85062239600&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85062239600&partnerID=8YFLogxK

U2 - 10.1002/slct.201803740

DO - 10.1002/slct.201803740

M3 - Article

VL - 4

SP - 2387

EP - 2391

JO - ChemistrySelect

JF - ChemistrySelect

SN - 2365-6549

IS - 8

ER -

Ulag S, Kalkandelen C, Oktar FN, Uzun M, Sahin YM, Karademir B et al. 3D Printing Artificial Blood Vessel Constructs Using PCL/Chitosan/Hydrogel Biocomposites. ChemistrySelect. 2019 Feb 28;4(8):2387-2391. https://doi.org/10.1002/slct.201803740