3D Printing Artificial Blood Vessel Constructs Using PCL/Chitosan/Hydrogel Biocomposites

Songul Ulag, Cevriye Kalkandelen, Faik Nuzhet Oktar, Muhammet Uzun, Yesim Muge Sahin, Betul Karademir, Sema Arslan, Ibrahim Tarik Ozbolat, Mahir Mahirogullari, Oguzhan Gunduz

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Abstract

The present paper aims to overcome the problems related to previous use of autologous grafts using available synthetic grafts. To examine the optimum of the ideal vessel-like constructs parameters are produced at 230 °C. At this production temperature, the elastic modulus values of the constructs ranges from 56 MPa to 174 MPa. The maximum cell proliferation is obtained from PCL/7wt.%CS/5wt.%H that is tested by mitochondrial dehydrogenase activity. The structures are visualized with all constructs after cell fixation by making use of the HUVEC cell line.

Original languageEnglish (US)
Pages (from-to)2387-2391
Number of pages5
JournalChemistrySelect
Volume4
Issue number8
DOIs
StatePublished - Feb 28 2019

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All Science Journal Classification (ASJC) codes

  • Chemistry(all)

Cite this

Ulag, S., Kalkandelen, C., Oktar, F. N., Uzun, M., Sahin, Y. M., Karademir, B., Arslan, S., Ozbolat, I. T., Mahirogullari, M., & Gunduz, O. (2019). 3D Printing Artificial Blood Vessel Constructs Using PCL/Chitosan/Hydrogel Biocomposites. ChemistrySelect, 4(8), 2387-2391. https://doi.org/10.1002/slct.201803740