3D segmentation of rodent brain structures using Active Volume Model with shape priors

Shaoting Zhang, Junzhou Huang, Mustafa Uzunbas, Tian Shen, Foteini Delis, Sharon Xiaolei Huang, Nora Volkow, Panayotis Thanos, Dimitris Metaxas

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

Object boundary extraction is an important task in brain image analysis. Acquiring detailed 3D representations of the brain structures could improve the detection rate of diseases at earlier stages. Deformable model based segmentation methods have been widely used with considerable success. Recently, 3D Active Volume Model (AVM) was proposed, which incorporates both gradient and region information for robustness. However, the segmentation performance of this model depends on the position, size and shape of the initialization, especially for data with complex texture. Furthermore, there is no shape prior information integrated. In this paper, we present an approach combining AVM and Active Shape Model (ASM). Our method uses shape information from training data to constrain the deformation of AVM. Experiments have been made on the segmentation of complex structures of the rodent brain from MR images, and the proposed method performed better than the original AVM.

Original languageEnglish (US)
Title of host publication2011 8th IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro, ISBI'11
Pages433-436
Number of pages4
DOIs
StatePublished - Nov 2 2011
Event2011 8th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI'11 - Chicago, IL, United States
Duration: Mar 30 2011Apr 2 2011

Publication series

NameProceedings - International Symposium on Biomedical Imaging
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452

Other

Other2011 8th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI'11
CountryUnited States
CityChicago, IL
Period3/30/114/2/11

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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    Zhang, S., Huang, J., Uzunbas, M., Shen, T., Delis, F., Huang, S. X., Volkow, N., Thanos, P., & Metaxas, D. (2011). 3D segmentation of rodent brain structures using Active Volume Model with shape priors. In 2011 8th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI'11 (pp. 433-436). [5872439] (Proceedings - International Symposium on Biomedical Imaging). https://doi.org/10.1109/ISBI.2011.5872439