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2013
47 Citations (Scopus)
DNA Damage
Cell Survival
Serum
Cell Death
Phosphorylation
77 Citations (Scopus)

Regulation of muscle protein synthesis and the effects of catabolic states

Gordon, B. S., Kelleher, A. R. & Kimball, S. R., Jan 1 2013, In : International Journal of Biochemistry and Cell Biology. 45, 10, p. 2147-2157 11 p.

Research output: Contribution to journalReview article

Muscle Proteins
Muscle
Skeletal Muscle
Protein Biosynthesis
Proteins
22 Citations (Scopus)

SAD-A kinase controls islet β-cell size and function as a mediator of mTORC1 signaling

Nie, J., Liu, X., Lilley, B. N., Zhang, H., Pan, Y. A., Kimball, S. R., Zhang, J., Zhang, W., Wang, L., Jefferson, L. S., Sanes, J. R., Han, X. & Shi, Y., Aug 28 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 34, p. 13857-13862 6 p.

Research output: Contribution to journalArticle

Mediator Complex
Islets of Langerhans
Cell Size
Synapses
Phosphotransferases
61 Citations (Scopus)
70-kDa Ribosomal Protein S6 Kinases
Hindlimb
Leucine
Skeletal Muscle
Phosphorylation
7 Citations (Scopus)

Viscera and muscle protein synthesis in neonatal pigs is increased more by intermittent bolus than by continuous feeding

El-Kadi, S. W., Gazzaneo, M. C., Suryawan, A., Orellana, R. A., Torrazza, R. M., Srivastava, N., Kimball, S. R., Nguyen, H. V., Fiorotto, M. L. & Davis, T. A., Aug 1 2013, In : Pediatric Research. 74, 2, p. 154-162 9 p.

Research output: Contribution to journalArticle

Viscera
Muscle Proteins
Meals
Swine
Skeletal Muscle
2012
9 Citations (Scopus)
Troponin T
RNA Precursors
Alternative Splicing
Sarcomeres
Weights and Measures
17 Citations (Scopus)
Phosphorylation
Endoplasmic Reticulum Stress
Gene expression
Liver
Gene Expression
18 Citations (Scopus)

Post-Translational Processing of Synaptophysin in the Rat Retina Is Disrupted by Diabetes

D'Cruz, T. S., Weibley, B. N., Kimball, S. R. & Barber, A. J., Sep 6 2012, In : PloS one. 7, 9, e44711.

Research output: Contribution to journalArticle

Synaptophysin
Medical problems
retina
diabetes
Retina
75 Citations (Scopus)
70-kDa Ribosomal Protein S6 Kinases
Apoptosis Regulatory Proteins
Phosphorylation
Cell death
Messenger RNA
75 Citations (Scopus)

Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B

Woo, C. W., Kutzler, L., Kimball, S. & Tabas, I., Feb 1 2012, In : Nature Cell Biology. 14, 2, p. 192-200 9 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Toll-Like Receptors
Guanine Nucleotide Exchange Factors
Unfolded Protein Response
Endoplasmic Reticulum
2011
14 Citations (Scopus)
troponin T
Troponin T
alternative splicing
Alternative Splicing
Insects
17 Citations (Scopus)

Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptome

Bixler, G. V., Vanguilder, H. D., Brucklacher, R. M., Kimball, S. R., Bronson, S. K. & Freeman, W. M., May 17 2011, In : BMC Medical Genomics. 4, 40.

Research output: Contribution to journalArticle

Transcriptome
Insulin
Therapeutics
Genes
Diabetic Retinopathy
14 Citations (Scopus)

Differential regulation of protein synthesis and mTOR signaling in skeletal muscle and visceral tissues of neonatal pigs after a meal

Gazzaneo, M. C., Orellana, R. A., Suryawan, A., Tuckow, A. P., Kimball, S. R., Wilson, F. A., Nguyen, H. V., Torrazza, R. M., Fiorotto, M. L. & Davis, T. A., Sep 1 2011, In : Pediatric Research. 70, 3, p. 253-260 8 p.

Research output: Contribution to journalArticle

TOR Serine-Threonine Kinases
Meals
Skeletal Muscle
Swine
Muscles
58 Citations (Scopus)
Tuberous Sclerosis
Phosphotransferases
GTP Phosphohydrolase Activators
Leucine
Sirolimus
16 Citations (Scopus)
Alcoholic Cardiomyopathy
Sex Characteristics
Proteomics
Alcohols
Proteins
15 Citations (Scopus)
Medical problems
Type 1 Diabetes Mellitus
Hyperglycemia
Liver
Phosphorylation
33 Citations (Scopus)

Intermittent bolus feeding has a greater stimulatory effect on protein synthesis in skeletal muscle than continuous feeding in neonatal pigs

Gazzaneo, M. C., Orellana, A. S., Torrazza, R. M., El-Kadi, S. W., Wilson, F. A., Kimball, S. R., Srivastava, N., Nguyen, H. V., Fiorotto, M. L. & Davis, T. A., Dec 1 2011, In : Journal of Nutrition. 141, 12, p. 2152-2158 7 p.

Research output: Contribution to journalArticle

Skeletal Muscle
Swine
Muscle Proteins
Meals
TOR Serine-Threonine Kinases
69 Citations (Scopus)

Mechanisms involved in the coordinate regulation of mTORC1 by insulin and amino acids

Dennis, M. D., Baum, J. I., Kimball, S. R. & Jefferson, L. S., Mar 11 2011, In : Journal of Biological Chemistry. 286, 10, p. 8287-8296 10 p.

Research output: Contribution to journalArticle

Insulin
Amino Acids
Chemical activation
Leucine
Raptors
41 Citations (Scopus)

Molecular characterization of skeletal muscle atrophy in the R6/2 mouse model of Huntington's disease

She, P., Zhang, Z., Marchionini, D., Diaz, W. C., Jetton, T. J., Kimball, S. R., Vary, T. C., Lang, C. H. & Lynch, C. J., Jul 1 2011, In : American Journal of Physiology - Endocrinology and Metabolism. 301, 1, p. E49-E61

Research output: Contribution to journalArticle

Muscular Atrophy
Huntington Disease
Skeletal Muscle
Muscles
Sirolimus
32 Citations (Scopus)

Multi-modal proteomic analysis of retinal protein expression alterations in a rat model of diabetic retinopathy

VanGuilder, H. D., Bixler, G. V., Kutzler, L., Brucklacher, R. M., Bronson, S. K., Kimball, S. R. & Freeman, W. M., Feb 1 2011, In : PloS one. 6, 1, e16271.

Research output: Contribution to journalArticle

diabetic retinopathy
Diabetic Retinopathy
Proteomics
proteomics
Rats
21 Citations (Scopus)
Mifepristone
Glucocorticoid Receptors
Biomarkers
DNA Damage
Muscle
15 Citations (Scopus)
Eukaryotic Initiation Factor-2B
Simvastatin
Cell Line
Muscles
Hydroxymethylglutaryl-CoA Reductase Inhibitors
16 Citations (Scopus)

The alpha subunit of eukaryotic initiation factor 2B (eIF2B) is required for eIF2-mediated translational suppression of vesicular stomatitis virus

Elsby, R., Heiber, J. F., Reid, P., Kimball, S. R., Pavitt, G. D. & Barber, G. N., Oct 1 2011, In : Journal of virology. 85, 19, p. 9716-9725 10 p.

Research output: Contribution to journalArticle

Eukaryotic Initiation Factor-2B
Vesiculovirus
Vesicular Stomatitis
translation (genetics)
Viruses