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2018
6 Citations (Scopus)

High turnover of extracellular matrix reflected by specific protein fragments measured in serum is associated with poor outcomes in two metastatic breast cancer cohorts

Lipton, A., Leitzel, K., Ali, S. M., Polimera, H. V., Nagabhairu, V., Marks, E., Richardson, A. E., Krecko, L., Ali, A., Koestler, W., Esteva, F. J., Leeming, D. J., Karsdal, M. A. & Willumsen, N., Dec 1 2018, In : International Journal of Cancer. 143, 11, p. 3027-3034 8 p.

Research output: Contribution to journalArticle

Metalloproteases
Extracellular Matrix
Collagen
Breast Neoplasms
Collagen Type III
4 Citations (Scopus)

The C-Terminal Intact Forms of Periostin (iPTN) Are Surrogate Markers for Osteolytic Lesions in Experimental Breast Cancer Bone Metastasis

Gineyts, E., Bonnet, N., Bertholon, C., Millet, M., Pagnon-Minot, A., Borel, O., Geraci, S., Bonnelye, E., Croset, M., Suhail, A., Truica, C., Lamparella, N., Leitzel, K., Hartmann, D., Chapurlat, R., Lipton, A., Garnero, P., Ferrari, S., Clézardin, P. & Rousseau, J. C., Nov 1 2018, In : Calcified Tissue International. 103, 5, p. 567-580 14 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Biomarkers
Breast Neoplasms
Neoplasm Metastasis
Bone and Bones
2017
45 Citations (Scopus)

Continued treatment effect of zoledronic acid dosing every 12 vs 4 weeks in women with breast cancer metastatic to bone: The OPTIMIZE-2 randomized clinical trial

Hortobagyi, G. N., Van Poznak, C., Harker, W. G., Gradishar, W. J., Chew, H., Dakhil, S. R., Haley, B. B., Sauter, N., Mohanlal, R., Zheng, M. & Lipton, A., Jul 2017, In : JAMA Oncology. 3, 7, p. 906-912 7 p.

Research output: Contribution to journalArticle

zoledronic acid
Randomized Controlled Trials
Breast Neoplasms
Bone and Bones
pamidronate
3 Citations (Scopus)

Impact of serum HER2, TIMP-1, and CAIX on outcome for HER2+ metastatic breast cancer patients: CCTG MA.31 (lapatinib vs. trastuzumab)

Ho, D., Huang, J., Chapman, J. A. W., Leitzel, K., Ali, S. M., Shepherd, L., Parulekar, W. R., Ellis, C. E., Crescnzo, R. J., Zhu, L., Virk, S., Nomikos, D., Aparicio, S., Gelmon, K. A., Carney, W. P. & Lipton, A., Aug 1 2017, In : Breast Cancer Research and Treatment. 164, 3, p. 571-580 10 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinase-1
Breast Neoplasms
Biomarkers
Serum
lapatinib
4 Citations (Scopus)

Osteoporosis therapy and outcomes for postmenopausal patients with hormone receptor–positive breast cancer: NCIC CTG MA.27

Lipton, A., Chapman, J. A. W., Leitzel, K., Garg, A., Pritchard, K. I., Ingle, J. N., Budd, G. T., Ellis, M. J., Sledge, G. W., Rabaglio, M., Han, L., Elliott, C. R., Shepherd, L. E., Goss, P. E. & Ali, S. M., Jul 1 2017, In : Cancer. 123, 13, p. 2444-2451 8 p.

Research output: Contribution to journalArticle

Osteoporosis
Hormones
Breast Neoplasms
Disease-Free Survival
Therapeutics
3 Citations (Scopus)

PTHrP(12-48) Modulates the Bone Marrow Microenvironment and Suppresses Human Osteoclast Differentiation and Lifespan

Kamalakar, A., Washam, C. L., Akel, N. S., Allen, B. J., Williams, D. K., Swain, F. L., Leitzel, K., Lipton, A., Gaddy, D. & Suva, L. J., Jul 1 2017, In : Journal of Bone and Mineral Research. 32, 7, p. 1421-1431 11 p.

Research output: Contribution to journalArticle

Parathyroid Hormone-Related Protein
Osteoclasts
Bone Marrow
Bone and Bones
Neoplasm Metastasis
2016
11 Citations (Scopus)

Changes in bone turnover marker levels and clinical outcomes in patients with advanced cancer and bone metastases treated with bone antiresorptive agents

Lipton, A., Smith, M. R., Fizazi, K., Stopeck, A. T., Henry, D., Brown, J. E., Shore, N. D., Saad, F., Spencer, A., Zhu, L. & Warner, D. J., Dec 1 2016, In : Clinical Cancer Research. 22, 23, p. 5713-5721 9 p.

Research output: Contribution to journalArticle

Bone Density Conservation Agents
Bone Neoplasms
Bone Remodeling
Biomarkers
Neoplasm Metastasis
46 Citations (Scopus)

Effect of denosumab versus zoledronic acid in preventing skeletal-related events in patients with bone metastases by baseline characteristics

Lipton, A., Fizazi, K., Stopeck, A. T., Henry, D. H., Smith, M. R., Shore, N., Martin, M., Vadhan-Raj, S., Brown, J. E., Richardson, G. E., Saad, F., Yardley, D. A., Zhou, K., Balakumaran, A. & Braun, A., Jan 1 2016, In : European Journal of Cancer. 53, p. 75-83 9 p.

Research output: Contribution to journalArticle

zoledronic acid
Neoplasm Metastasis
Bone and Bones
Denosumab
Neoplasms
7 Citations (Scopus)

N-telopeptide of type I collagen long-term dynamics in breast cancer patients with bone metastases: Clinical outcomes and influence of extraskeletal metastases

Ferreira, A. R., Alho, I., Shan, N., Matias, M., Faria, M., Casimiro, S., Leitzel, K., Ali, S., Lipton, A. & Costa, L., Dec 2016, In : Oncologist. 21, 12, p. 1418-1426 9 p.

Research output: Contribution to journalArticle

Collagen Type I
zoledronic acid
Breast Neoplasms
Neoplasm Metastasis
Bone and Bones
2015
10 Citations (Scopus)

Antiresorptive Therapy in the Management of Cancer Treatment-Induced Bone Loss

Garg, A., Leitzel, K., Ali, S. & Lipton, A., Jan 1 2015, In : Current Osteoporosis Reports. 13, 2, p. 73-77 5 p.

Research output: Contribution to journalReview article

Bone and Bones
Neoplasms
Therapeutics
Breast Neoplasms
Prostatic Neoplasms
52 Citations (Scopus)

Hypocalcaemia in patients with metastatic bone disease treated with denosumab

Body, J. J., Bone, H. G., De Boer, R. H., Stopeck, A., Van Poznak, C., Damião, R., Fizazi, K., Henry, D. H., Ibrahim, T., Lipton, A., Saad, F., Shore, N., Takano, T., Shaywitz, A. J., Wang, H., Bracco, O. L., Braun, A. & Kostenuik, P. J., Aug 8 2015, In : European Journal of Cancer. 51, 13, p. 1812-1821 10 p., 9488.

Research output: Contribution to journalArticle

Hypocalcemia
Bone Diseases
zoledronic acid
Calcium
Bone and Bones
2014

Bone-Related Issues in Oncology

Mujtaba Rizvi, S., Collins, H. & Lipton, A., Jun 20 2014, Cancer Consult: Expertise for Clinical Practice. Wiley-Blackwell, p. 867-871 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Bone and Bones
Aromatase Inhibitors
Androgens
Therapeutics
Osteoporosis
22 Citations (Scopus)

Circulating interleukin-8 levels explain breast cancer osteolysis in mice and humans

Kamalakar, A., Bendre, M. S., Washam, C. L., Fowler, T. W., Carver, A., Dilley, J. D., Bracey, J. W., Akel, N. S., Margulies, A. G., Skinner, R. A., Swain, F. L., Hogue, W. R., Montgomery, C. O., Lahiji, P., Maher, J. J., Leitzel, K. E., Ali, S. M., Lipton, A., Nicholas, R. W., Gaddy, D. & 1 others, Suva, L. J., Apr 1 2014, In : Bone. 61, p. 176-185 10 p.

Research output: Contribution to journalArticle

Osteolysis
Interleukin-8
Breast Neoplasms
Bone Resorption
Bone Neoplasms
10 Citations (Scopus)

Elevation in multiple serum inflammatory biomarkers predicts survival of pancreatic cancer patients with inoperable disease

Alkhateeb, A., Zubritsky, L., Kinsman, B., Leitzel, K., Campbell-Baird, C., Ali, S. M., Connor, J. & Lipton, A., Jun 2014, In : Journal of Gastrointestinal Cancer. 45, 2, p. 161-167 7 p.

Research output: Contribution to journalArticle

Ferritins
Pancreatic Neoplasms
C-Reactive Protein
Biomarkers
Survival

Hypercalcemia

Morton, A. R. & Lipton, A., Jan 1 2014, Abeloff's Clinical Oncology: Fifth Edition. Elsevier Inc., p. 581-590 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hypercalcemia

New Targeted Therapies for Bone Metastases

Lipton, A., Costa, L., Sieber, P., Dougall, W. C. & Braun, A., Mar 4 2014, Bone Metastases: A translational and Clinical Approach. Vassiliou, V., Chow, E. & Kardamakis, D. (eds.). 1 ed. p. 235-246 12 p. (Cancer Metastasis - Biology and Treatment; vol. 21, no. 1).

Research output: Chapter in Book/Report/Conference proceedingChapter

Neoplasm Metastasis
Bone and Bones
zoledronic acid
RANK Ligand
Therapeutics
8 Citations (Scopus)

Would screening for lung cancer benefit 75- to 84-year-old residents of the United States?

Varlotto, J. M., DeCamp, M. M., Flickinger, J. C., Lake, J., Recht, A., Belani, C. P., Reed, M. F., Toth, J. W., Mackley, H. B., Sciamanna, C. N., Lipton, A., Ali, S. M., Mahraj, R. P. M., Gilbert, C. R. & Yao, N., Jan 1 2014, In : Frontiers in Oncology. 4 MAR, Article 37.

Research output: Contribution to journalArticle

Lung Neoplasms
Age Groups
Survival
Non-Small Cell Lung Carcinoma
Therapeutics
2013

Cancer Treatment-Induced Bone Loss in Patients with Breast Cancer: Pathophysiology and Clinical Perspectives

Lipton, A., Dansey, R. & Coleman, R., Jun 2013, Osteoporosis: Fourth Edition. Elsevier Inc., p. 1445-1454 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Breast Neoplasms
Bone and Bones
Neoplasms
Aromatase Inhibitors
zoledronic acid
41 Citations (Scopus)

HER3, p95HER2, and HER2 protein expression levels define multiple subtypes of HER2-positive metastatic breast cancer

Lipton, A., Goodman, L., Leitzel, K., Cook, J., Sperinde, J., Haddad, M., Köstler, W. J., Huang, W., Weidler, J. M., Ali, S., Newton, A., Fuchs, E. M., Paquet, A., Singer, C. F., Horvat, R., Jin, X., Banerjee, J., Mukherjee, A., Tan, Y., Shi, Y. & 9 others, Chenna, A., Larson, J., Lie, Y., Sherwood, T., Petropoulos, C. J., Williams, S., Winslow, J., Parry, G. & Bates, M., Aug 1 2013, In : Breast Cancer Research and Treatment. 141, 1, p. 43-53 11 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Proteins
Biomarkers
Therapeutics
Decision Trees
30 Citations (Scopus)

Identification of PTHrP(12-48) as a plasma biomarker associated with breast cancer bone metastasis

Washam, C. L., Byrum, S. D., Leitzel, K., Ali, S. M., Tackett, A. J., Gaddy, D., Sundermann, S. E., Lipton, A. & Suva, L. J., May 1 2013, In : Cancer Epidemiology Biomarkers and Prevention. 22, 5, p. 972-983 12 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Biomarkers
Breast Neoplasms
Neoplasm Metastasis
Area Under Curve
4 Citations (Scopus)

Impact of genetic targets on prostate cancer therapy

Sheikh, H., Abdulghani, J., Ali, S., Sinha, R. & Lipton, A., Feb 15 2013, Impact of Genetic Targets on Cancer Therapy. El-Deiry, W. (ed.). p. 359-383 25 p. (Advances in Experimental Medicine and Biology; vol. 779).

Research output: Chapter in Book/Report/Conference proceedingChapter

Prostatic Neoplasms
Pharmaceutical Preparations
Therapeutics
Inborn Genetic Diseases
Survival
85 Citations (Scopus)

Pain outcomes in patients with advanced breast cancer and bone metastases: Results from a randomized, double-blind study of denosumab and zoledronic acid

Cleeland, C. S., Body, J. J., Stopeck, A., Von Moos, R., Fallowfield, L., Mathias, S. D., Patrick, D. L., Clemons, M., Tonkin, K., Masuda, N., Lipton, A., De Boer, R., Salvagni, S., Oliveira, C. T., Qian, Y., Jiang, Q., Dansey, R., Braun, A. & Chung, K., Feb 15 2013, In : Cancer. 119, 4, p. 832-838 7 p.

Research output: Contribution to journalArticle

zoledronic acid
Bone Neoplasms
Double-Blind Method
Breast Neoplasms
Neoplasm Metastasis
16 Citations (Scopus)

Possible survival benefits from zoledronic acid treatment in patients with bone metastases from solid tumours and poor prognostic features - An exploratory analysis of placebo-controlled trials

Coleman, R. E., Lipton, A., Costa, L., Cook, R. J., Lee, K. A., Saad, F., Brown, J. E., Terpos, E., Major, P. P., Kohno, N., Smith, M. & Body, J. J., Jun 2013, In : Journal of Bone Oncology. 2, 2, p. 70-76 7 p.

Research output: Contribution to journalArticle

zoledronic acid
Placebos
Neoplasm Metastasis
Bone and Bones
Survival
44 Citations (Scopus)

RANKL/RANK/MMP-1 Molecular Triad Contributes to the Metastatic Phenotype of Breast and Prostate Cancer Cells In Vitro

Casimiro, S., Mohammad, K. S., Pires, R., Tato-Costa, J., Alho, I., Teixeira, R., Carvalho, A., Ribeiro, S., Lipton, A., Guise, T. A. & Costa, L., May 16 2013, In : PloS one. 8, 5, e63153.

Research output: Contribution to journalArticle

interstitial collagenase
prostatic neoplasms
Matrix Metalloproteinases
breast neoplasms
Prostatic Neoplasms
2 Citations (Scopus)

RANKL enhances the effect of an antagonist of inhibitor of apoptosis proteins (cIAPs) in RANK-positive breast cancer cells

Casimiro, S., Alho, I., Bettencourt, M., Pires, R., Lipton, A. & Costa, L., 2013, In : Journal of Bone Oncology. 2, 3, p. 116-122 7 p.

Research output: Contribution to journalArticle

Inhibitor of Apoptosis Proteins
Breast Neoplasms
Neoplasms
Osteoclasts
Apoptosis
2 Citations (Scopus)

Reply to Araki et al.

Lipton, A., Fizazi, K., Stopeck, A. T., Henry, D. H. & Braun, A. H., Jun 1 2013, In : European Journal of Cancer. 49, 9, p. 2266-2268 3 p.

Research output: Contribution to journalLetter

Bone Density Conservation Agents
Imidazoles
Antibodies, Monoclonal, Humanized
Bone Neoplasms
Diphosphonates
25 Citations (Scopus)

Skeletal-related events and clinical outcomes in patients with bone metastases and normal levels of osteolysis: Exploratory analyses

Lipton, A., Cook, R., Brown, J., Body, J. J., Smith, M. & Coleman, R., Apr 1 2013, In : Clinical Oncology. 25, 4, p. 217-226 10 p.

Research output: Contribution to journalArticle

Osteolysis
zoledronic acid
Neoplasm Metastasis
Bone and Bones
Creatinine
14 Citations (Scopus)

Treatment of bone metastases before the onset of pain

Costa, L., Lipton, A., Hadji, P., Chen, Y. M. & Kosmidis, P., Jun 1 2013, In : International Journal of Clinical Oncology. 18, 3, p. 531-538 8 p.

Research output: Contribution to journalArticle

zoledronic acid
Neoplasm Metastasis
Bone and Bones
Pain
pamidronate
2012
48 Citations (Scopus)

Cancer treatment-induced bone loss in premenopausal women: A need for therapeutic intervention?

Hadji, P., Gnant, M., Body, J. J., Bundred, N. J., Brufsky, A., Coleman, R. E., Guise, T. A., Lipton, A. & Aapro, M. S., Oct 1 2012, In : Cancer Treatment Reviews. 38, 6, p. 798-806 9 p.

Research output: Contribution to journalReview article

Bone and Bones
Neoplasms
Breast Neoplasms
Therapeutics
Diphosphonates
13 Citations (Scopus)
Bone and Bones
zoledronic acid
Osteoclasts
Neoplasms
Neoplasm Metastasis
21 Citations (Scopus)

Elevation in Inflammatory Serum Biomarkers Predicts Response to Trastuzumab-Containing Therapy

Alkhateeb, A. A., Leitzel, K., Ali, S. M., Campbell-Baird, C., Evans, M., Fuchs, E. M., Köstler, W. J., Lipton, A. & Connor, J., Dec 29 2012, In : PloS one. 7, 12, e51379.

Research output: Contribution to journalArticle

Biomarkers
biomarkers
Ferritins
C-Reactive Protein
therapeutics
15 Citations (Scopus)

Prognostic role of serum parathyroid hormone levels in advanced prostate cancer patients undergoing zoledronic acid administration

Berruti, A., Cook, R., Saad, F., Buttigliero, C., Lipton, A., Tampellini, M., Lee, K. A., Coleman, R. E. & Smith, M. R., Jun 4 2012, In : Oncologist. 17, 5, p. 645-652 8 p.

Research output: Contribution to journalArticle

zoledronic acid
Parathyroid Hormone
Prostatic Neoplasms
Serum
Secondary Hyperparathyroidism
43 Citations (Scopus)

Serum lactate dehydrogenase is prognostic for survival in patients with bone metastases from breast cancer: A retrospective analysis in bisphosphonate-treated patients

Brown, J. E., Cook, R. J., Lipton, A. & Coleman, R. E., Nov 15 2012, In : Clinical Cancer Research. 18, 22, p. 6348-6355 8 p.

Research output: Contribution to journalArticle

zoledronic acid
Diphosphonates
L-Lactate Dehydrogenase
Breast Neoplasms
Neoplasm Metastasis
313 Citations (Scopus)

Superiority of denosumab to zoledronic acid for prevention of skeletal-related events: A combined analysis of 3 pivotal, randomised, phase 3 trials

Lipton, A., Fizazi, K., Stopeck, A. T., Henry, D. H., Brown, J. E., Yardley, D. A., Richardson, G. E., Siena, S., Maroto, P., Clemens, M., Bilynskyy, B., Charu, V., Beuzeboc, P., Rader, M., Viniegra, M., Saad, F., Ke, C., Braun, A. & Jun, S., Nov 1 2012, In : European Journal of Cancer. 48, 16, p. 3082-3092 11 p.

Research output: Contribution to journalArticle

zoledronic acid
Bone and Bones
Disease Progression
Prostatic Neoplasms
Neoplasm Metastasis
15 Citations (Scopus)

Treatment-induced bone loss and fractures in cancer patients undergoing hormone ablation therapy: Efficacy and safety of Denosumab

Lipton, A., Smith, M. R., Ellis, G. K. & Goessl, C., Jan 1 2012, In : Clinical Medicine Insights: Oncology. 6, p. 287-303 17 p.

Research output: Contribution to journalReview article

Bone Fractures
Hormones
Safety
Neoplasms
Osteoclasts
2011
27 Citations (Scopus)

Anticancer evidence for zoledronic acid across the cancer continuum

Costa, L., Harper, P., Coleman, R. E. & Lipton, A., Feb 1 2011, In : Critical Reviews in Oncology/Hematology. 77, SUPPL.1

Research output: Contribution to journalReview article

zoledronic acid
Neoplasms
Clinical Trials
Circulating Neoplastic Cells
Residual Neoplasm
3 Citations (Scopus)
zoledronic acid
Diphosphonates
Breast
Breast Neoplasms
Bone and Bones
16 Citations (Scopus)

Bone turnover markers: Tools for prognosis and monitoring response to bisphosphonates?

Lipton, A., Costa, L. & Coleman, R. E., Dec 1 2011, In : Breast Disease. 33, 2, p. 59-69 11 p.

Research output: Contribution to journalReview article

Bone Remodeling
Diphosphonates
Bone and Bones
Neoplasm Metastasis
zoledronic acid
41 Citations (Scopus)

Clinical development of anti-RANKL therapies for treatment and prevention of bone metastasis

Lipton, A. & Goessl, C., Jan 1 2011, In : Bone. 48, 1, p. 96-99 4 p.

Research output: Contribution to journalReview article

RANK Ligand
Neoplasm Metastasis
Bone and Bones
Osteoclasts
Bone Neoplasms
55 Citations (Scopus)

Consensus on the utility of bone markers in the malignant bone disease setting

Coleman, R., Costa, L., Saad, F., Cook, R., Hadji, P., Terpos, E., Garnero, P., Brown, J., Body, J. J., Smith, M., Lee, K. A., Major, P., Dimopoulos, M. & Lipton, A., Dec 1 2011, In : Critical Reviews in Oncology/Hematology. 80, 3, p. 411-432 22 p.

Research output: Contribution to journalReview article

Bone Diseases
Bone and Bones
zoledronic acid
Neoplasm Metastasis
Neoplasms
22 Citations (Scopus)

Denosumab: Benefits of RANK ligand inhibition in cancer patients

Lipton, A. & Jacobs, I., Sep 1 2011, In : Current Opinion in Supportive and Palliative Care. 5, 3, p. 258-264 7 p.

Research output: Contribution to journalReview article

RANK Ligand
Neoplasms
Neoplasm Metastasis
Bone and Bones
zoledronic acid
4 Citations (Scopus)

Denosumab in breast cancer

Lipton, A., Feb 1 2011, In : Current oncology reports. 13, 1, p. 1-4 4 p.

Research output: Contribution to journalArticle

zoledronic acid
NF-kappa B
Osteoclasts
Breast Neoplasms
Bone and Bones
8 Citations (Scopus)

Dosing of zoledronic acid throughout the treatment continuum in breast cancer

Hadji, P., Gnant, M., Aapro, M., Lipton, A. & Coleman, R., Aug 1 2011, In : Critical Reviews in Oncology/Hematology. 79, 2, p. 175-188 14 p.

Research output: Contribution to journalReview article

zoledronic acid
Breast Neoplasms
Therapeutics
Bone and Bones
Recurrence
42 Citations (Scopus)

Elevated bone turnover predicts for bone metastasis in postmenopausal breast cancer: Results of NCIC CTG MA.14

Lipton, A., Chapman, J. A. W., Demers, L., Shepherd, L. E., Han, L., Wilson, C. F., Pritchard, K. I., Leitzel, K. E., Ali, S. M. & Pollak, M., Sep 20 2011, In : Journal of Clinical Oncology. 29, 27, p. 3605-3610 6 p.

Research output: Contribution to journalArticle

Bone Remodeling
Breast Neoplasms
Neoplasm Metastasis
Bone and Bones
Recurrence
24 Citations (Scopus)

Elevated plasma tissue inhibitor of metalloproteinase-1 levels predict decreased survival in castration-resistant prostate cancer patients

Oh, W. K., Vargas, R., Jacobus, S., Leitzel, K., Regan, M. M., Hamer, P., Pierce, K., Brown-Shimer, S., Carney, W., Ali, S. M., Kantoff, P. W. & Lipton, A., Feb 1 2011, In : Cancer. 117, 3, p. 517-525 9 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinase-1
Castration
Prostatic Neoplasms
Survival
Neoplasm Grading
2 Citations (Scopus)

How do we define efficacy in comparing osteoclast-targeted agents in metastatic breast cancer?

Gralow, J. R., Lipton, A. & Stopeck, A. T., Sep 10 2011, In : Journal of Clinical Oncology. 29, 26, p. 3591-3592 2 p.

Research output: Contribution to journalLetter

Bone Density Conservation Agents
Bone Neoplasms
Osteoclasts
Breast Neoplasms
10 Citations (Scopus)

Human epidermal growth factor receptor 2 (HER2) extracellular domain levels are associated with progression-free survival in patients with HER2-positive metastatic breast cancer receiving lapatinib monotherapy

Lipton, A., Leitzel, K., Ali, S. M., Carney, W., Platek, G., Steplewski, K., Westlund, R., Gagnon, R., Martin, A. M. & Maltzman, J., Nov 1 2011, In : Cancer. 117, 21, p. 5013-5020 8 p.

Research output: Contribution to journalArticle

Disease-Free Survival
Breast Neoplasms
Serum
human ERBB2 protein
lapatinib
21 Citations (Scopus)

Identification of a subpopulation of metastatic breast cancer patients with very high HER2 expression levels and possible resistance to trastuzumab

Bates, M., Sperinde, J., Köstler, W. J., Ali, S. M., Leitzel, K., Fuchs, E. M., Paquet, A., Lie, Y., Sherwood, T., Horvat, R., Singer, C. F., Winslow, J., Weidler, J. M., Huang, W. & Lipton, A., Sep 1 2011, In : Annals of Oncology. 22, 9, p. 2014-2020 7 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Kaplan-Meier Estimate
Neoplasms
Survival Analysis
human ERBB2 protein
14 Citations (Scopus)

Improving progression-free and overall survival in patients with cancer: A potential role for bisphosphonates

Lipton, A., Apr 1 2011, In : Expert Opinion on Pharmacotherapy. 12, 5, p. 749-762 14 p.

Research output: Contribution to journalReview article

Diphosphonates
Disease-Free Survival
Neoplasms
Multiple Myeloma
Expert Testimony
25 Citations (Scopus)

Lactoferrin-endothelin-1 axis contributes to the development and invasiveness of triple-negative breast cancer phenotypes

Ha, N. H., Nair, V. S., Reddy, D. N. S., Mudvari, P., Ohshiro, K., Ghanta, K. S., Pakala, S. B., Li, D. Q., Costa, L., Lipton, A., Badwe, R. A., Fuqua, S., Wallon, M., Prendergast, G. C. & Kumar, R., Dec 1 2011, In : Cancer Research. 71, 23, p. 7259-7269 11 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Lactoferrin
Endothelin-1
Phenotype
Breast Neoplasms