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2019
Alcohol Drinking
Muscle
Skeletal Muscle
Alcohols
Muscles
TOR Serine-Threonine Kinases
Autophagy
Muscle
Skeletal Muscle
Ethanol
High Fat Diet
GABA-A Receptors
Stomach
Neurons
Brain Stem

Resistin directly inhibits bacterial killing in neutrophils

Miller, L., Singbartl, K., Chroneos, Z., Ruiz-Velasco, V., Lang, C. & Bonavia, A., May 30 2019, In : Intensive Care Medicine Experimental. 7, 30

Research output: Contribution to journalArticle

Open Access
2018
1 Citation (Scopus)

Acute alcohol prevents the refeeding-induced decrease in autophagy but does not alter the increased protein synthetic response in heart

Mekheal, M., Steiner, J. L. & Lang, C., Dec 1 2018, In : Alcohol. 73, p. 79-88 10 p.

Research output: Contribution to journalArticle

Autophagy
Ethanol
alcohol
Alcohols
redistribution
1 Citation (Scopus)

Combination of hindlimb suspension and immobilization by casting exaggerates sarcopenia by stimulating autophagy but does not worsen osteopenia

Speacht, T. L., Krause, A. R., Steiner, J. L., Lang, C. H. & Donahue, H. J., May 2018, In : Bone. 110, p. 29-37 9 p.

Research output: Contribution to journalArticle

Sarcopenia
Hindlimb Suspension
Metabolic Bone Diseases
Autophagy
Muscles
3 Citations (Scopus)

Effects of phytonutrients alone or in combination with monensin on productivity in lactating dairy cows

Oh, J., Harper, M., Lang, C., Wall, E. H. & Hristov, A. N., Aug 1 2018, In : Journal of dairy science. 101, 8, p. 7190-7198 9 p.

Research output: Contribution to journalArticle

Monensin
Capsicum
monensin
Phytochemicals
Eugenol
1 Citation (Scopus)
Muscle Proteins
Sex Characteristics
Alcohols
Proteins
Estrus
2 Citations (Scopus)

Mechanisms underlying muscle protein imbalance induced by alcohol

Kimball, S. & Lang, C., Aug 21 2018, In : Annual Review of Nutrition. 38, p. 197-217 21 p.

Research output: Contribution to journalReview article

Muscle Proteins
Alcohols
Skeletal Muscle
Autophagy
Sirolimus
1 Citation (Scopus)

Temporally distinct regulation of pathways contributing to cardiac proteostasis during the acute and recovery phases of sepsis

Crowell, K. T., Moreno, S., Steiner, J. L., Coleman, C. S., Soybel, D. I. & Lang, C. H., Jan 1 2018, In : Shock. 50, 6, p. 616-626 11 p.

Research output: Contribution to journalArticle

Inflammasomes
Sepsis
Proteasome Endopeptidase Complex
Proteins
Apoptosis
2017
17 Citations (Scopus)

Alcohol, adipose tissue and lipid dysregulation

Steiner, J. L. & Lang, C. H., Feb 16 2017, In : Biomolecules. 7, 1, 16.

Research output: Contribution to journalReview article

Adipose Tissue
Alcohols
Tissue
Lipids
White Adipose Tissue
6 Citations (Scopus)

Alcoholic Cardiomyopathy: Disrupted Protein Balance and Impaired Cardiomyocyte Contractility

Steiner, J. L. & Lang, C. H., Aug 1 2017, In : Alcoholism: Clinical and Experimental Research. 41, 8, p. 1392-1401 10 p.

Research output: Contribution to journalReview article

Alcoholic Cardiomyopathy
Cardiac Myocytes
Alcohols
Proteins
Metabolism
21 Citations (Scopus)

Etiology of alcoholic cardiomyopathy: Mitochondria, oxidative stress and apoptosis

Steiner, J. L. & Lang, C. H., Aug 1 2017, In : International Journal of Biochemistry and Cell Biology. 89, p. 125-135 11 p.

Research output: Contribution to journalReview article

Alcoholic Cardiomyopathy
Mitochondria
Oxidative stress
Oxidative Stress
Alcohols
7 Citations (Scopus)

FoxO1-AMPK-ULK1 Regulates Ethanol-Induced Autophagy in Muscle by Enhanced ATG14 Association with the BECN1-PIK3C3 Complex

Hong-Brown, L. Q., Brown, C. R., Navaratnarajah, M. & Lang, C. H., May 2017, In : Alcoholism: Clinical and Experimental Research. 41, 5, p. 895-910 16 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Autophagy
Muscle
Ethanol
Phosphorylation
2 Citations (Scopus)

Immune and metabolic responses in early and late sepsis during mild dietary zinc restriction

Crowell, K. T., Phillips, B. E., Kelleher, S. L., Soybel, D. I. & Lang, C. H., Apr 1 2017, In : Journal of Surgical Research. 210, p. 47-58 12 p.

Research output: Contribution to journalArticle

Zinc
Sepsis
Liver
Punctures
Interferon-gamma
3 Citations (Scopus)
White Adipose Tissue
Autophagy
Proteasome Endopeptidase Complex
Sepsis
Apoptosis

Preface

Schisler, J. C., Lang, C. & Willis, M. S., Jan 1 2017, Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart. Elsevier Inc., p. xxi-xxii

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

6 Citations (Scopus)

RESTORATIVE MECHANISMS REGULATING PROTEIN BALANCE in SKELETAL MUSCLE during RECOVERY from SEPSIS

Crowell, K. T., Soybel, D. I. & Lang, C. H., Apr 1 2017, In : Shock. 47, 4, p. 463-473 11 p.

Research output: Contribution to journalArticle

Sepsis
Phosphorylation
Proteins
Muscle Proteins
Autophagy
7 Citations (Scopus)

Simulated space radiation sensitizes bone but not muscle to the catabolic effects of mechanical unloading

Krause, A. R., Speacht, T. L., Zhang, Y., Lang, C. H. & Donahue, H. J., Aug 2017, In : PloS one. 12, 8, e0182403.

Research output: Contribution to journalArticle

Unloading
limbs (animal)
Muscle
Bone
bones
2016
11 Citations (Scopus)

Acute alcohol-induced decrease in muscle protein synthesis in female mice is REDD-1 and mTOR-independent

Steiner, J. L., Kimball, S. R. & Lang, C. H., May 1 2016, In : Alcohol and Alcoholism. 51, 3, p. 242-250 9 p.

Research output: Contribution to journalArticle

Muscle Proteins
Alcohols
Proteins
Proteasome Endopeptidase Complex
Ubiquitin
6 Citations (Scopus)

Alcohol and inflammatory responses: Highlights of the 2015 Alcohol and Immunology Research Interest Group (AIRIG) meeting

Cannon, A. R., Morris, N. L., Hammer, A. M., Curtis, B., Remick, D. G., Yeligar, S. M., Poole, L., Burnham, E. L., Wyatt, T. A., Molina, P. E., So-Armah, K., Cisneros, T., Wang, G., Lang, C. H., Mandrekar, P., Kovacs, E. J. & Choudhry, M. A., Aug 1 2016, In : Alcohol. 54, p. 73-77 5 p.

Research output: Contribution to journalReview article

Immunology
Public Opinion
Group Processes
research interest
Allergy and Immunology
37 Citations (Scopus)

Control of skeletal muscle atrophy in response to disuse: Clinical/preclinical contentions and fallacies of evidence

Atherton, P. J., Greenhaff, P. L., Phillips, S. M., Bodine, S. C., Adams, C. M. & Lang, C. H., Sep 1 2016, In : American Journal of Physiology - Endocrinology and Metabolism. 311, 3, p. E594-E604

Research output: Contribution to journalReview article

Muscular Atrophy
Muscle Proteins
Atrophic Muscular Disorders
Skeletal Muscle
Muscles
13 Citations (Scopus)
White Adipose Tissue
Autophagy
Alcohol Drinking
Adipose Tissue
Chemical activation
5 Citations (Scopus)
Rumen
proteasome endopeptidase complex
Proteasome Endopeptidase Complex
Sirolimus
ubiquitin
18 Citations (Scopus)
DNA Damage
Skeletal Muscle
Proteins
Muscle Proteins
Alcoholism

Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart

Schisler, J. C., Lang, C. & Willis, M. S., Nov 4 2016, Elsevier Inc. 354 p.

Research output: Book/ReportBook

Endocrinology
Hormones
Pathology
Health
Molecular Biology
1 Citation (Scopus)

Marginal dietary zinc deprivation augments sepsis-induced alterations in skeletal muscle TNF-α but not protein synthesis

Crowell, K. T., Kelleher, S. L., Soybel, D. I. & Lang, C. H., Nov 1 2016, In : Physiological reports. 4, 21, e13017.

Research output: Contribution to journalArticle

Zinc
Sepsis
Skeletal Muscle
Muscle Proteins
Proteins
5 Citations (Scopus)

Physiological processes underlying organ injury in alcohol abuse

Souza-Smith, F. M., Lang, C. H., Nagy, L. E., Bailey, S. M., Parsons, L. H. & Murray, G. J., Sep 1 2016, In : American Journal of Physiology - Endocrinology and Metabolism. 311, 3, p. E605-E619

Research output: Contribution to journalReview article

Physiological Phenomena
Alcoholism
National Institute on Alcohol Abuse and Alcoholism (U.S.)
Wounds and Injuries
Alcohols

Preface

Schisler, J. C., Lang, C. & Willis, M. S., Nov 4 2016, Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart. Elsevier Inc., p. xxi-xxii

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

2015
15 Citations (Scopus)

Adamts1 mediates ethanol-induced alterations in collagen and elastin via a FoxO1-sestrin3-AMPK signaling cascade in myocytes

Hong-Brown, L. Q., Brown, C. R., Navaratnarajah, M. & Lang, C. H., Jan 1 2015, In : Journal of cellular biochemistry. 116, 1, p. 91-101 11 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Elastin
Muscle Cells
Ethanol
Collagen
8 Citations (Scopus)

Alcohol Differentially Alters Extracellular Matrix and Adhesion Molecule Expression in Skeletal Muscle and Heart

Steiner, J. L., Pruznak, A. M., Navaratnarajah, M. & Lang, C. H., Aug 1 2015, In : Alcoholism: Clinical and Experimental Research. 39, 8, p. 1330-1340 11 p.

Research output: Contribution to journalArticle

Extracellular Matrix
Muscle
Skeletal Muscle
Adhesion
Alcohols
13 Citations (Scopus)
Alcoholic Intoxication
Signal transduction
Muscle Proteins
Sirolimus
Muscle Contraction
14 Citations (Scopus)
DNA Damage
Sepsis
Skeletal Muscle
Genes
Autophagy
47 Citations (Scopus)

Dysregulation of skeletal muscle protein metabolism by alcohol

Steiner, J. L. & Lang, C. H., Jan 1 2015, In : American Journal of Physiology - Endocrinology and Metabolism. 308, 9, p. E699-E712

Research output: Contribution to journalReview article

Muscle Proteins
Skeletal Muscle
Alcohols
TOR Serine-Threonine Kinases
Proteins
1 Citation (Scopus)

Expression of Concern

Chaudry, I. H. & Lang, C. H., Jun 4 2015, In : Shock. 43, 6, 1 p.

Research output: Contribution to journalComment/debate

Hemofiltration
Blood Circulation
Acute Kidney Injury
Sepsis
Hemodynamics
31 Citations (Scopus)

Impact of alcohol on glycemic control and insulin action

Steiner, J. L., Crowell, K. T. & Lang, C. H., Jan 1 2015, In : Biomolecules. 5, 4, p. 2223-2246 24 p., A05.

Research output: Contribution to journalArticle

Alcohols
Insulin
Tissue
Medical problems
Metabolism
15 Citations (Scopus)

Moderate alcohol consumption does not impair overloadinduced muscle hypertrophy and protein synthesis

Steiner, J. L., Gordon, B. S. & Lang, C. H., Jan 1 2015, In : Physiological reports. 3, 3, e12333.

Research output: Contribution to journalArticle

Muscle Proteins
Alcohol Drinking
Hypertrophy
Skeletal Muscle
Muscles
2 Citations (Scopus)
Sympathetic Ganglia
G-Protein-Coupled Receptors
abdomen
Abdomen
Neurons
31 Citations (Scopus)
DNA Damage
Skeletal Muscle
Food
Proteins
mechanistic target of rapamycin complex 1
13 Citations (Scopus)

Sepsis attenuates the anabolic response to skeletal muscle contraction

Steiner, J. L. & Lang, C. H., Apr 16 2015, In : Shock. 43, 4, p. 344-351 8 p.

Research output: Contribution to journalArticle

Muscle Contraction
Sepsis
Skeletal Muscle
Phosphorylation
Punctures
2014
91 Citations (Scopus)

Abandon the mouse research ship? Not just yet!

Osuchowski, M. F., Remick, D. G., Lederer, J. A., Lang, C. H., Aasen, A. O., Aibiki, M., Azevedo, L. C., Bahrami, S., Boros, M., Cooney, R., Cuzzocrea, S., Jiang, Y., Junger, W. G., Hirasawa, H., Hotchkiss, R. S., Li, X. A., Radermacher, P., Redl, H., Salomao, R., Soebandrio, A. & 7 others, Thiemermann, C., Vincent, J. L., Ward, P., Yao, Y. M., Yu, H. P., Zingarelli, B. & Chaudry, I. H., Jun 2014, In : Shock. 41, 6, p. 463-475 13 p.

Research output: Contribution to journalReview article

Ships
Critical Care
Research
Endotoxemia
Wounds and Injuries
24 Citations (Scopus)
Muscle Proteins
Sirolimus
Muscle Contraction
Skeletal Muscle
Alcohols
23 Citations (Scopus)
Inbred F344 Rats
Alcohol Drinking
Alcohols
Proteins
Phosphorylation
15 Citations (Scopus)

Chronic alcohol ingestion in rats alters lung metabolism, promotes lipid accumulation, and impairs alveolar macrophage functions

Romero, F., Shah, D., Duong, M., Stafstrom, W., Hoek, J. B., Kallen, C. B., Lang, C. H. & Summer, R., Dec 1 2014, In : American journal of respiratory cell and molecular biology. 51, 6, p. 840-849 10 p.

Research output: Contribution to journalArticle

Alveolar Macrophages
Lipid Metabolism
Rats
Eating
Alcohols
10 Citations (Scopus)

Disruption of genes encoding eIF4E binding proteins-1 and -2 does not alter basal or sepsis-induced changes in skeletal muscle protein synthesis in male or female mice

Steiner, J. L., Pruznak, A. M., Deiter, G., Navaratnarajah, M., Kutzler, L., Kimball, S. R. & Lang, C. H., Jun 19 2014, In : PloS one. 9, 6, e99582.

Research output: Contribution to journalArticle

Phosphorylation
Gene encoding
Muscle Proteins
muscle protein
gene targeting
12 Citations (Scopus)

Glucocorticoids attenuate the central sympathoexcitatory actions of insulin

Steiner, J. L., Bardgett, M. E., Wolfgang, L., Lang, C. H. & Stocker, S. D., Nov 15 2014, In : Journal of neurophysiology. 112, 10, p. 2597-2604 8 p.

Research output: Contribution to journalArticle

Glucocorticoids
Insulin
Dexamethasone
Arcuate Nucleus of Hypothalamus
Eating
42 Citations (Scopus)

Interdependence of muscle atrophy and bone loss induced by mechanical unloading

Lloyd, S. A., Lang, C. H., Zhang, Y., Paul, E. M., Laufenberg, L. J., Lewis, G. S. & Donahue, H. J., Jan 1 2014, In : Journal of Bone and Mineral Research. 29, 5, p. 1118-1130 13 p.

Research output: Contribution to journalArticle

Hindlimb Suspension
Muscular Atrophy
Bone and Bones
Femur
Tibia
22 Citations (Scopus)
Muscle Contraction
DNA Damage
Proteins
Sciatic Nerve
Electric Stimulation
19 Citations (Scopus)

Sepsis-induced changes in amino acid transporters and leucine signaling via mTOR in skeletal muscle

Laufenberg, L. J., Pruznak, A. M., Navaratnarajah, M. & Lang, C. H., Dec 2014, In : Amino Acids. 46, 12, p. 2787-2798 12 p.

Research output: Contribution to journalArticle

Amino Acid Transport Systems
Leucine
Muscle
Sepsis
Skeletal Muscle
15 Citations (Scopus)
Muscle
Rats
Myocardium
Skeletal Muscle
Ethanol