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2019

C-O Bond Dissociation and Induced Chemical Ionization Using High Energy (CO2)n+ Gas Cluster Ion Beam

Tian, H., Maciążek, D., Postawa, Z., Garrison, B. J. & Winograd, N., Mar 15 2019, In : Journal of the American Society for Mass Spectrometry. 30, 3, p. 476-481 6 p.

Research output: Contribution to journalArticle

Ion beams
Ionization
Gases
Ions
Oxygen

Enhanced Ion Yields Using High Energy Water Cluster Beams for Secondary Ion Mass Spectrometry Analysis and Imaging

Sheraz, S., Tian, H., Vickerman, J. C., Blenkinsopp, P., Winograd, N. & Cumpson, P., May 28 2019, In : Analytical chemistry. 91, 14, p. 9058-9068 11 p.

Research output: Contribution to journalArticle

Secondary ion mass spectrometry
Ions
Imaging techniques
Water
Argon
1 Citation (Scopus)

Ionization probability of sputtered indium under irradiation with 20-keV fullerene and argon gas cluster projectiles

Wucher, A., Breuer, L. & Winograd, N., Apr 1 2019, In : International Journal of Mass Spectrometry. 438, p. 13-21 9 p.

Research output: Contribution to journalArticle

Fullerenes
Indium
Argon
Projectiles
fullerenes
3 Citations (Scopus)

Mass spectrometry-based tissue imaging: The next frontier in clinical diagnostics?

Leung, F., Eberlin, L. S., Schwamborn, K., Heeren, R. M. A., Winograd, N. & Graham, R., Apr 2019, In : Clinical Chemistry. 65, 4, p. 510-513 4 p.

Research output: Contribution to journalComment/debate

Open Access
Mass spectrometry
Mass Spectrometry
Tissue
Imaging techniques
3 Citations (Scopus)

Molecular SIMS Ionization Probability Studied with Laser Postionization: Influence of the Projectile Cluster

Breuer, L., Tian, H., Wucher, A. & Winograd, N., Oct 1 2019, In : Journal of Physical Chemistry C. 123, 1, p. 565-574 10 p.

Research output: Contribution to journalArticle

Projectiles
Secondary ion mass spectrometry
secondary ion mass spectrometry
Ionization
projectiles
3 Citations (Scopus)

Secondary-Ion Mass Spectrometry Images Cardiolipins and Phosphatidylethanolamines at the Subcellular Level

Tian, H., Sparvero, L. J., Blenkinsopp, P., Amoscato, A. A., Watkins, S. C., Bayır, H., Kagan, V. E. & Winograd, N., Mar 4 2019, In : Angewandte Chemie - International Edition. 58, 10, p. 3156-3161 6 p.

Research output: Contribution to journalArticle

Phosphatidylethanolamines
Cardiolipins
Phospholipids
Cell death
Projectiles
2018
9 Citations (Scopus)

Gas Cluster Ion Beams for Secondary Ion Mass Spectrometry

Winograd, N., Jun 12 2018, In : Annual Review of Analytical Chemistry. 11, p. 29-48 20 p.

Research output: Contribution to journalReview article

Secondary ion mass spectrometry
Ion beams
Gases
Depth profiling
Kinetic energy
2017
2 Citations (Scopus)

Effect of SIMS ionization probability on depth resolution for organic/inorganic interfaces

Popczun, N. J., Breuer, L., Wucher, A. & Winograd, N., Oct 2017, In : Surface and Interface Analysis. 49, 10, p. 933-939 7 p.

Research output: Contribution to journalArticle

Secondary ion mass spectrometry
secondary ion mass spectrometry
Ionization
ionization
Depth profiling
33 Citations (Scopus)

Gas Cluster Ion Beam Time-of-Flight Secondary Ion Mass Spectrometry High-Resolution Imaging of Cardiolipin Speciation in the Brain: Identification of Molecular Losses after Traumatic Injury

Tian, H., Sparvero, L. J., Amoscato, A. A., Bloom, A., Baylr, H., Kagan, V. E. & Winograd, N., Apr 18 2017, In : Analytical chemistry. 89, 8, p. 4611-4619 9 p.

Research output: Contribution to journalArticle

Cardiolipins
Secondary ion mass spectrometry
Ion beams
Brain
Gases
9 Citations (Scopus)

Ionization Probability in Molecular Secondary Ion Mass Spectrometry: Protonation Efficiency of Sputtered Guanine Molecules Studied by Laser Postionization

Popczun, N. J., Breuer, L., Wucher, A. & Winograd, N., Apr 27 2017, In : Journal of Physical Chemistry C. 121, 16, p. 8931-8937 7 p.

Research output: Contribution to journalArticle

guanines
Protonation
Guanine
Secondary ion mass spectrometry
secondary ion mass spectrometry
6 Citations (Scopus)

Label-free visualization of nilotinib-functionalized gold nanoparticles within single mammalian cells by C60- SIMS imaging

Bloom, A. N., Tian, H., Schoen, C. & Winograd, N., May 1 2017, In : Analytical and Bioanalytical Chemistry. 409, 12, p. 3067-3076 10 p.

Research output: Contribution to journalArticle

Secondary ion mass spectrometry
Gold
Nanoparticles
Labels
Visualization
12 Citations (Scopus)

On the SIMS Ionization Probability of Organic Molecules

Popczun, N. J., Breuer, L., Wucher, A. & Winograd, N., Jun 1 2017, In : Journal of the American Society for Mass Spectrometry. 28, 6, p. 1182-1191 10 p.

Research output: Contribution to journalArticle

Secondary Ion Mass Spectrometry
Secondary ion mass spectrometry
Ionization
Ions
Molecules
5 Citations (Scopus)

Reducing the Matrix Effect in Molecular Secondary Ion Mass Spectrometry by Laser Post-Ionization

Breuer, L., Popczun, N. J., Wucher, A. & Winograd, N., Sep 14 2017, In : Journal of Physical Chemistry C. 121, 36, p. 19705-19715 11 p.

Research output: Contribution to journalArticle

Secondary ion mass spectrometry
secondary ion mass spectrometry
Ionization
ionization
Molecules
31 Citations (Scopus)

Subcellular Chemical Imaging of Antibiotics in Single Bacteria Using C60-Secondary Ion Mass Spectrometry

Tian, H., Six, D. A., Krucker, T., Leeds, J. A. & Winograd, N., May 2 2017, In : Analytical chemistry. 89, 9, p. 5050-5057 8 p.

Research output: Contribution to journalArticle

Secondary ion mass spectrometry
Tetracycline
Bacteria
Anti-Bacterial Agents
Imaging techniques
2016
5 Citations (Scopus)

C60-SIMS imaging of nanoparticles within mammalian cells

Bloom, A. N., Tian, H. & Winograd, N., Jun 1 2016, In : Biointerphases. 11, 2, p. 1-7 7 p.

Research output: Contribution to journalArticle

Secondary Ion Mass Spectrometry
Secondary ion mass spectrometry
Nanoparticles
secondary ion mass spectrometry
Cells
1 Citation (Scopus)

Cluster secondary ion mass spectrometry imaging of interfacial reactions of TiO2 microspheres embedded in ionic liquids

Shen, K., Tarolli, J. G. & Winograd, N., Feb 15 2016, In : Rapid Communications in Mass Spectrometry. 30, 3, p. 379-385 7 p.

Research output: Contribution to journalArticle

Ionic Liquids
Secondary ion mass spectrometry
Surface chemistry
Microspheres
Depth profiling
16 Citations (Scopus)

CO2 Cluster Ion Beam, an Alternative Projectile for Secondary Ion Mass Spectrometry

Tian, H., Maciążek, D., Postawa, Z., Garrison, B. J. & Winograd, N., Sep 1 2016, In : Journal of the American Society for Mass Spectrometry. 27, 9, p. 1476-1482 7 p.

Research output: Contribution to journalArticle

Secondary Ion Mass Spectrometry
Argon
Projectiles
Secondary ion mass spectrometry
Ion beams
10 Citations (Scopus)

Dynamic Reactive Ionization with Cluster Secondary Ion Mass Spectrometry

Tian, H., Wucher, A. & Winograd, N., Feb 1 2016, In : Journal of the American Society for Mass Spectrometry. 27, 2, p. 285-292 8 p.

Research output: Contribution to journalArticle

Secondary Ion Mass Spectrometry
Secondary ion mass spectrometry
Trehalose
Ionization
Ions
3 Citations (Scopus)

Multimodal image fusion with SIMS: Preprocessing with image registration

Tarolli, J. G., Bloom, A. & Winograd, N., Jan 1 2016, In : Biointerphases. 11, 2, p. 2A311-1-2A311-10

Research output: Contribution to journalArticle

Secondary Ion Mass Spectrometry
Image fusion
Image registration
preprocessing
Secondary ion mass spectrometry
10 Citations (Scopus)

Reduce the matrix effect in biological tissue imaging using dynamic reactive ionization and gas cluster ion beams

Tian, H., Wucher, A. & Winograd, N., Jun 1 2016, In : Biointerphases. 11, 2, 02A320.

Research output: Contribution to journalArticle

Secondary Ion Mass Spectrometry
Secondary ion mass spectrometry
cerebellum
Cerebellum
Lipids
10 Citations (Scopus)

Reducing the Matrix Effect in Organic Cluster SIMS Using Dynamic Reactive Ionization

Tian, H., Wucher, A. & Winograd, N., Dec 1 2016, In : Journal of the American Society for Mass Spectrometry. 27, 12, p. 2014-2024 11 p.

Research output: Contribution to journalArticle

Secondary ion mass spectrometry
Depth profiling
Ionization
Ions
Trehalose
2015
2 Citations (Scopus)

Erratum: Measuring Compositions in Organic Depth Profiling: Results from a VAMAS Interlaboratory Study (Journal of Physical Chemistry B (2015) 119 (33) (10784-10797) DOI: 10.1021/acs.jpcb.5b05625)

Shard, A. G., Havelund, R., Spencer, S. J., Gilmore, I. S., Alexander, M. R., Angerer, T. B., Aoyagi, S., Barnes, J. P., Benayad, A., Bernasik, A., Ceccone, G., Counsell, J. D. P., Deeks, C., Fletcher, J. S., Graham, D. J., Heuser, C., Lee, T. G., Marie, C., Marzec, M. M., Mishra, G. & 14 others, Rading, D., Renault, O., Scurr, D. J., Shon, H. K., Spampinato, V., Tian, H., Wang, F., Winograd, N., Wu, K., Wucher, A., Zhou, Y., Zhu, Z., Cristaudo, V. & Poleunis, C., Nov 5 2015, In : Journal of Physical Chemistry B. 119, 44, 1 p.

Research output: Contribution to journalComment/debate

Physical chemistry
Depth profiling
Chemical analysis
24 Citations (Scopus)

Imaging mass spectrometry on the nanoscale with cluster ion beams

Winograd, N., Jan 6 2015, In : Analytical chemistry. 87, 1, p. 328-333 6 p.

Research output: Contribution to journalReview article

Projectiles
Ion beams
Mass spectrometry
Imaging techniques
Secondary ion mass spectrometry
32 Citations (Scopus)

Measuring Compositions in Organic Depth Profiling: Results from a VAMAS Interlaboratory Study

Shard, A. G., Havelund, R., Spencer, S. J., Gilmore, I. S., Alexander, M. R., Angerer, T. B., Aoyagi, S., Barnes, J. P., Benayad, A., Bernasik, A., Ceccone, G., Counsell, J. D. P., Deeks, C., Fletcher, J. S., Graham, D. J., Heuser, C., Lee, T. G., Marie, C., Marzec, M. M., Mishra, G. & 12 others, Rading, D., Renault, O., Scurr, D. J., Shon, H. K., Spampinato, V., Tian, H., Wang, F., Winograd, N., Wu, K., Wucher, A., Zhou, Y. & Zhu, Z., Aug 20 2015, In : Journal of Physical Chemistry B. 119, 33, p. 10784-10797 14 p.

Research output: Contribution to journalArticle

Depth profiling
Secondary ion mass spectrometry
secondary ion mass spectrometry
Volume fraction
Ions
20 Citations (Scopus)

Molecular Depth Profiling with Argon Gas Cluster Ion Beams

Shen, K., Wucher, A. & Winograd, N., Jul 9 2015, In : Journal of Physical Chemistry C. 119, 27, p. 15316-15324 9 p.

Research output: Contribution to journalArticle

Depth profiling
Argon
Kinetic energy
Ion beams
Gases
4 Citations (Scopus)

Sample preparation for 3D SIMS chemical imaging of cells

Winograd, N. & Bloom, A., Jan 1 2015, In : Methods in Molecular Biology. 1203, p. 9-19 11 p.

Research output: Contribution to journalArticle

Secondary Ion Mass Spectrometry
Ions

Sample preparation for 3D SIMS chemical imaging of cells

Winograd, N. & Bloom, A., Jan 1 2015, In : Methods in Molecular Biology. 1203, p. 9-19 11 p.

Research output: Contribution to journalArticle

Secondary Ion Mass Spectrometry
Ions
31 Citations (Scopus)

SIMS-A precursor and partner to contemporary mass spectrometry

Vickerman, J. C. & Winograd, N., Jan 1 2015, In : International Journal of Mass Spectrometry. 377, 1, p. 568-579 12 p.

Research output: Contribution to journalArticle

Secondary ion mass spectrometry
secondary ion mass spectrometry
Mass spectrometry
mass spectroscopy
bombardment
2014
27 Citations (Scopus)
Secondary ion mass spectrometry
Ion beams
Ionization
Gases
Ions
5 Citations (Scopus)

Application of pan-sharpening to SIMS imaging

Tarolli, J., Tian, H. & Winograd, N., Nov 1 2014, In : Surface and Interface Analysis. 46, S1, p. 217-220 4 p.

Research output: Contribution to journalArticle

Secondary ion mass spectrometry
secondary ion mass spectrometry
Imaging techniques
Image fusion
Image resolution
6 Citations (Scopus)

Characterization of hydroxyapatite deposition on biomimetic polyphosphazenes by time-of-flight secondary ion mass spectrometry (ToF-SIMS)

Morozowich, N. L., Lerach, J. O., Modzelewski, T., Jackson, L., Winograd, N. & Allcock, H. R., 2014, In : RSC Advances. 4, 38, p. 19680-19689 10 p.

Research output: Contribution to journalArticle

Biomimetics
Durapatite
Secondary ion mass spectrometry
Hydroxyapatite
Polymers

Cluster secondary ion mass spectrometrys

Kozole, J. & Winograd, N., Jan 1 2014, Surface Analysis and Techniques in Biology. Springer International Publishing, p. 71-98 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Secondary Ion Mass Spectrometry
Projectiles
Secondary ion mass spectrometry
Ions
Imaging techniques
3 Citations (Scopus)

Dye-enhanced imaging of mammalian cells with SIMS

Bloom, A. & Winograd, N., Nov 1 2014, In : Surface and Interface Analysis. 46, S1, p. 177-180 4 p.

Research output: Contribution to journalArticle

Secondary ion mass spectrometry
secondary ion mass spectrometry
Coloring Agents
Dyes
dyes
10 Citations (Scopus)

Formation of neutral InmCn clusters under C60 Ion bombardment of indium

Breuer, L., Kucher, A., Herder, M., Wucher, A. & Winograd, N., Sep 18 2014, In : Journal of Physical Chemistry A. 118, 37, p. 8542-8552 11 p.

Research output: Contribution to journalArticle

Indium
Ion bombardment
indium
bombardment
Carbon
15 Citations (Scopus)

Improving secondary ion mass spectrometry image quality with image fusion

Tarolli, J. G., Jackson, L. M. & Winograd, N., Dec 2014, In : Journal of the American Society for Mass Spectrometry. 25, 12, p. 2154-2162 9 p.

Research output: Contribution to journalArticle

Secondary Ion Mass Spectrometry
Image fusion
Secondary ion mass spectrometry
Image quality
Electrons
1 Citation (Scopus)

Investigations into the interactions of a MALDI matrix with organic thin films using C60+ SIMS depth profiling

Lerach, J. O., Keskin, S. & Winograd, N., Nov 1 2014, In : Surface and Interface Analysis. 46, S1, p. 67-69 3 p.

Research output: Contribution to journalArticle

Depth profiling
Secondary ion mass spectrometry
secondary ion mass spectrometry
Ionization
Thin films
10 Citations (Scopus)

Molecular imaging of biological tissue using gas cluster ions

Tian, H., Wucher, A. & Winograd, N., Nov 1 2014, In : Surface and Interface Analysis. 46, S1, p. 115-117 3 p.

Research output: Contribution to journalArticle

Molecular imaging
Gases
Ions
Tissue
Lipids
9 Citations (Scopus)

Near infrared (NIR) strong field ionization and imaging of C60 sputtered molecules: Overcoming matrix effects and improving sensitivity

Kucher, A., Jackson, L. M., Lerach, J. O., Bloom, A. N., Popczun, N. J., Wucher, A. & Winograd, N., Sep 2 2014, In : Analytical chemistry. 86, 17, p. 8613-8620 8 p.

Research output: Contribution to journalArticle

Ionization
Ions
Infrared radiation
Mass spectrometry
Imaging techniques
11 Citations (Scopus)

Strong field ionization of β-estradiol in the IR: Strategies to optimize molecular postionization in secondary neutral mass spectrometry

Kucher, A., Wucher, A. & Winograd, N., Nov 6 2014, In : Journal of Physical Chemistry C. 118, 44, p. 25534-25544 11 p.

Research output: Contribution to journalArticle

Ionization
Mass spectrometry
Estradiol
mass spectroscopy
Ions
1 Citation (Scopus)

Tandem MS and C60 SIMS for the identification and characterization of lipids

Durairaj, A. & Winograd, N., Nov 1 2014, In : Surface and Interface Analysis. 46, S1, p. 118-122 5 p.

Research output: Contribution to journalArticle

Secondary ion mass spectrometry
Lipids
secondary ion mass spectrometry
lipids
dissociation
2013
4 Citations (Scopus)

An experimental and theoretical view of energetic C60 cluster bombardment onto molecular solids

Brenes, D. A., Postawa, Z., Wucher, A., Blenkinsopp, P., Garrison, B. J. & Winograd, N., Jan 1 2013, In : Surface and Interface Analysis. 45, 1, p. 50-53 4 p.

Research output: Contribution to journalArticle

bombardment
Molecules
molecules
computerized simulation
Kinetic energy
4 Citations (Scopus)

A statistical interpretation of molecular delta layer depth profiles

Wucher, A., Krantzman, K. D., Lu, C. & Winograd, N., Jan 1 2013, In : Surface and Interface Analysis. 45, 1, p. 39-41 3 p.

Research output: Contribution to journalArticle

Sputtering
profiles
sputtering
Silicon
Full width at half maximum
5 Citations (Scopus)

C60-SIMS studies of glycerophospholipid in a LIPID MAPS model system: KDO2-Lipid A stimulated RAW 264.7 cells

Passarelli, M. K., Ewing, A. G. & Winograd, N., Jan 1 2013, In : Surface and Interface Analysis. 45, 1, p. 298-301 4 p.

Research output: Contribution to journalArticle

Glycerophospholipids
Lipid A
Secondary ion mass spectrometry
Lipids
secondary ion mass spectrometry
25 Citations (Scopus)

C60-ToF SIMS imaging of frozen hydrated HeLa cells

Piwowar, A. M., Keskin, S., Delgado, M. O., Shen, K., Hue, J. J., Lanekoff, I., Ewing, A. G. & Winograd, N., Jan 1 2013, In : Surface and Interface Analysis. 45, 1, p. 302-304 3 p.

Research output: Contribution to journalArticle

Secondary ion mass spectrometry
secondary ion mass spectrometry
Imaging techniques
Ethane
Silicon
11 Citations (Scopus)

Cluster TOF-SIMS Imaging and the Characterization of Biological Materials

Vickerman, J. & Winograd, N., Apr 15 2013, Cluster Secondary Ion Mass Spectrometry: Principles and Applications. John Wiley and Sons, p. 269-312 44 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Secondary ion mass spectrometry
Biological materials
Imaging techniques
Mass spectrometers
Ions

Comparative biochemical analysis of biological pretreatment of wood biomass with white rot fungi using Sum Frequency Generation (SFG) Spectroscopy and Secondary Ion Mass Spectrometry (SIMS)

Rajangam, A., Kafle, K., Jackson, L., Maher, T., Dazen, K., Lee, C., Winograd, N., Kim, S. & Curtis, W. R., 2013, Forest and Plant Bioproducts Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. AIChE, p. 80-81 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Secondary ion mass spectrometry
Fungi
Wood
Biomass
Spectroscopy

Comparative biochemical analysis of biological pretreatment of wood biomass with white Rot Fungi using sum frequency generation (SFG) spectroscopy and Secondary Ion Mass Spectrometry (SIMS)

Rajangam, A., Kafle, K., Jackson, L., Maher, T., Dazen, K., Lee, C., Winograd, N., Kim, S. & Curtis, W. R., Jan 1 2013, Sustainable Engineering Forum 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. AIChE, p. 291-292 2 p. (Sustainable Engineering Forum 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Secondary ion mass spectrometry
Fungi
Wood
Biomass
Spectroscopy
10 Citations (Scopus)

Depth profiling of metal overlayers on organic substrates with cluster SIMS

Shen, K., Mao, D., Garrison, B. J., Wucher, A. & Winograd, N., Nov 5 2013, In : Analytical chemistry. 85, 21, p. 10565-10572 8 p.

Research output: Contribution to journalArticle

Depth profiling
Secondary ion mass spectrometry
Gold
Metals
Erosion
32 Citations (Scopus)

Direct observation of ion distributions near electrodes in ionic polymer actuators containing ionic liquids

Liu, Y., Lu, C., Twigg, S., Ghaffari, M., Lin, J., Winograd, N. & Zhang, Q. M., Apr 9 2013, In : Scientific reports. 3, 973.

Research output: Contribution to journalArticle

Ionic Liquids
Polymers
Electrodes
Observation
Secondary Ion Mass Spectrometry
1 Citation (Scopus)

Evidence for the formation of dynamically created pre-formed ions at the interface of isotopically enriched thin films

Lerach, J. O. & Winograd, N., Jan 1 2013, In : Surface and Interface Analysis. 45, 1, p. 54-56 3 p.

Research output: Contribution to journalArticle

phenylalanine
Ions
Thin films
thin films
molecular ions