A 7 tesla fMRI study of amygdala responses to fearful faces

Wietske Van Der Zwaag, Sandra E. Da Costa, Nicole R. Zürcher, Reginald B. Adams, Nouchine Hadjikhani

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

The amygdalae are involved in the perception of emotions such as happiness, anger and fear. Because of their proximity to the sinuses, the image signal intensity in T2*weighted fMRI data is often affected by signal loss due to through-slice dephasing, especially at high field strength. In this study, the feasibility of fMRI in the amygdalae at 7 Tesla was investigated. A paradigm based on the presentation of fearful faces was used for stimulation. Previously, opposite effects have been found for presentation of averted and direct gaze fearful faces. Here, we show that (1) sufficiently high temporal SNR values are reached in the amygdalae for detection of small BOLD signal changes and (2) that the BOLD signal in the amygdalae for presentation of a direct or averted gaze in a fearful face depends on stimulus duration.

Original languageEnglish (US)
Pages (from-to)125-128
Number of pages4
JournalBrain Topography
Volume25
Issue number2
DOIs
StatePublished - Apr 1 2012

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Amygdala
Magnetic Resonance Imaging
Happiness
Anger
Fear
Emotions

All Science Journal Classification (ASJC) codes

  • Anatomy
  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Clinical Neurology

Cite this

Van Der Zwaag, W., Da Costa, S. E., Zürcher, N. R., Adams, R. B., & Hadjikhani, N. (2012). A 7 tesla fMRI study of amygdala responses to fearful faces. Brain Topography, 25(2), 125-128. https://doi.org/10.1007/s10548-012-0219-0
Van Der Zwaag, Wietske ; Da Costa, Sandra E. ; Zürcher, Nicole R. ; Adams, Reginald B. ; Hadjikhani, Nouchine. / A 7 tesla fMRI study of amygdala responses to fearful faces. In: Brain Topography. 2012 ; Vol. 25, No. 2. pp. 125-128.
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Van Der Zwaag, W, Da Costa, SE, Zürcher, NR, Adams, RB & Hadjikhani, N 2012, 'A 7 tesla fMRI study of amygdala responses to fearful faces', Brain Topography, vol. 25, no. 2, pp. 125-128. https://doi.org/10.1007/s10548-012-0219-0

A 7 tesla fMRI study of amygdala responses to fearful faces. / Van Der Zwaag, Wietske; Da Costa, Sandra E.; Zürcher, Nicole R.; Adams, Reginald B.; Hadjikhani, Nouchine.

In: Brain Topography, Vol. 25, No. 2, 01.04.2012, p. 125-128.

Research output: Contribution to journalArticle

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Van Der Zwaag W, Da Costa SE, Zürcher NR, Adams RB, Hadjikhani N. A 7 tesla fMRI study of amygdala responses to fearful faces. Brain Topography. 2012 Apr 1;25(2):125-128. https://doi.org/10.1007/s10548-012-0219-0