A Case Report of Wernicke's Encephalopathy in a Pediatric Patient with Anorexia Nervosa - Restricting Type

Todd E. Peters, Matthew Parvin, Christopher Petersen, Vivian C. Faircloth, Richard L. Levine

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

Purpose: To describe a case of Wernicke's encephalopathy in a 15-year-old female patient with anorexia nervosa - restricting type. Method: The patient and family were interviewed. Literature relevant to the case was reviewed prior to diagnosis. Results: The patient reported a 30-kg weight loss over a 6-month period, following a strict diet deplete in thiamine without vitamin supplementation. The patient reported a carbohydrate binge for 5 days prior to admission. Her clinical presentation, confusion, ataxia, nystagmus, and magnetic resonance imaging demonstrating bilateral subthalamic hyperdensities were consistent with Wernicke's encephalopathy. Nutritional stabilization and parenteral thiamine replacement resulted in rapid improvement of her ataxia and nystagmus and contributed to her recovery. Conclusions: Wernicke's encephalopathy should be considered in patients with anorexia nervosa. Thiamine therapy could be considered in cases of anorexia nervosa with significant confusion.

Original languageEnglish (US)
Pages (from-to)376-383
Number of pages8
JournalJournal of Adolescent Health
Volume40
Issue number4
DOIs
StatePublished - Apr 1 2007

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Public Health, Environmental and Occupational Health
  • Psychiatry and Mental health

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