A clinical and histopathologic study of granulomatous rosacea

Klaus Helm, Jennifer Menz, Lawrence E. Gibson, Charles H. Dicken

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Abstract

A retrospective clinical and histopathologic study of 53 patients with granulomatous rosacea was undertaken. The patients had a broad clinical spectrum of lesions that ranged from primarily erythema to papulonodular lesions. Extrafacial lesions occurred in 15% of patients. Histologic examination showed mixed lymphohistiocytic inflammation (primarily lymphocytic inflammation in 40% of patients and primarily histiocytic with a few giant cells in 34%), epithelioid granulomas in 11% of patients, and epithelioid granulomas with caseation necrosis in 11%. Most patients had a good response to oral antibiotic therapy. Granulomatous rosacea is not a distinct disease but can be regarded and treated as a subtype of rosacea.

Original languageEnglish (US)
Pages (from-to)1038-1043
Number of pages6
JournalJournal of the American Academy of Dermatology
Volume25
Issue number6
DOIs
Publication statusPublished - Jan 1 1991

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All Science Journal Classification (ASJC) codes

  • Dermatology

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