A clinical trial of indomethacin and ibuprofen in dysmenorrhea

D. R. Halbert, Laurence Demers

Research output: Contribution to journalArticle

19 Scopus citations


Forty patients with primary dysmenorrhea were treated with antiprostaglandin agents. Seventeen were treated with indomethacin, with 71% obtaining significant relief. Of 23 treated with ibuprofen, 87% obtained significant relief. Nausea occurred in 49%, vomiting in 23% and stool frequency in 35%. All of these gastrointestinal symptoms were relieved by both drugs. Ibuprofen was free of side effects, but four patients had headaches or peculiar psychic effects on indomethacin.

Original languageEnglish (US)
Pages (from-to)219-222
Number of pages4
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Issue number4
StatePublished - Dec 1 1978


All Science Journal Classification (ASJC) codes

  • Reproductive Medicine
  • Obstetrics and Gynecology

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