A community hospital develops an integrated, comprehensive toxicology laboratory

J. A. Rock, C. Cecil Cuppett

Research output: Contribution to journalArticle

Abstract

A model system was developed at the author's institution for providing toxicology and therapeutic drug monitoring services. These services were expanded with chromatography instrumentation and the Syva EMIT-st Drug Detection System. An emergency screen for various drugs in urine takes about one hour. The drugs or drug families detected are opiates, barbiturates, benzodiazepines, amphetamines, phenothiazines, cocaine metabolite, acetaminophen, and ethyl alcohol. Confirmation and quantitation of drugs in serum can be done by either higher performance liquid chromatography, gas chromatography, or radioimmunoassay. Sample preparation takes from five to 15 minutes and chromatography requires about 15 minutes in most cases. While more than 60 drugs can be quantitated using these procedures, rarely are more than one or two drugs present in patient samples.

Original languageEnglish (US)
Pages (from-to)235-237
Number of pages3
JournalPathologist
Volume38
Issue number4
StatePublished - Jan 1 1984

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Community Hospital
Toxicology
Pharmaceutical Preparations
Chromatography
Opiate Alkaloids
Phenothiazines
Amphetamines
Barbiturates
Drug Monitoring
Acetaminophen
Benzodiazepines
Cocaine
Gas Chromatography
Radioimmunoassay
Emergencies
Ethanol
High Pressure Liquid Chromatography
Urine
Serum

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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A community hospital develops an integrated, comprehensive toxicology laboratory. / Rock, J. A.; Cuppett, C. Cecil.

In: Pathologist, Vol. 38, No. 4, 01.01.1984, p. 235-237.

Research output: Contribution to journalArticle

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