A comparison of phase organization of model segmented polyurethanes with different intersegment compatibilities

Rebeca Hernandez, Jadwiga Weksler, Ajay Padsalgikar, Choi Taeyi, Elena Angelo, J. S. Lin, Lichong Xu, Christopher Siedlecki, James Patrick Runt

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127 Scopus citations


Three series of chemically well-defined polyurethanes were synthesized with the same hard segments but different soft-segment chemistries of interest in biomedical applications. The multiblock polyurethanes have soft segments composed of either an aliphatic polycarbonate [poly(l,6-hexyl 1,2-ethyl carbonate)], polytetram- ethylenoxide, or a mixed macrodiol of polyhexamethylenoxide and hydroxyl-terminated poly(dimethylsiloxane) and the same hard-segment chemistry [4,4′-methylenediphenyl diisocyanate and 1,4-butanediol]. Analysis using small-angle X-ray scattering and other methods demonstrates that demixing of the hard and soft segments varies greatly between the three series of copolymers. For example, the PDMS/PHMO-based copolymers exhibit a three-phase, core - shell morphology, while the other two series exhibit a typical two-phase structure. In addition to quantitative measurements of hard/soft-segment demixing for the two-phase copolymers, FTIR spectroscopy was used to assess inter- and intracomponent hydrogen bonding, and tapping mode AFM was used to characterize the nanoscale morphology.

Original languageEnglish (US)
Pages (from-to)9767-9776
Number of pages10
Issue number24
StatePublished - Dec 23 2008


All Science Journal Classification (ASJC) codes

  • Organic Chemistry
  • Polymers and Plastics
  • Inorganic Chemistry
  • Materials Chemistry

Cite this

Hernandez, R., Weksler, J., Padsalgikar, A., Taeyi, C., Angelo, E., Lin, J. S., Xu, L., Siedlecki, C., & Runt, J. P. (2008). A comparison of phase organization of model segmented polyurethanes with different intersegment compatibilities. Macromolecules, 41(24), 9767-9776. https://doi.org/10.1021/ma8014454