A comparison of the major surfactant-associated proteins in different species

David Phelps, H. William Taeusch

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

1. 1. We examined the major surfactant-associated proteins in a number of species by using two-dimensional gel electrophoresis, protein blotting and immunostaining. 2. 2. All species have a 30,000 to 35,000 mol. wt protein group consisting of multiple isoforms with isoelectric points ranging from pH 4.4 to 5.6. 3. 3. The techniques used in this study have resolved three component subgroups within the 35 K group. 4. 4. A group of proteins at 60,000-65,000 mol. wt has also been consistently identified. 5. 5. We conclude that remarkable similarity exists among the major surfactant-associated proteins from various mammals with regard to isoelectric points, molecular weights and antigenic sites.

Original languageEnglish (US)
Pages (from-to)441-446
Number of pages6
JournalComparative Biochemistry and Physiology -- Part B: Biochemistry and
Volume82
Issue number3
DOIs
StatePublished - Jan 1 1985

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Surface-Active Agents
Isoelectric Point
Proteins
Mammals
Electrophoresis, Gel, Two-Dimensional
Electrophoresis
Protein Isoforms
Molecular Weight
Gels
Molecular weight

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physiology
  • Molecular Biology

Cite this

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A comparison of the major surfactant-associated proteins in different species. / Phelps, David; Taeusch, H. William.

In: Comparative Biochemistry and Physiology -- Part B: Biochemistry and, Vol. 82, No. 3, 01.01.1985, p. 441-446.

Research output: Contribution to journalArticle

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