A comparison of the major surfactant-associated proteins in different species

David Phelps, H. William Taeusch

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

1. 1. We examined the major surfactant-associated proteins in a number of species by using two-dimensional gel electrophoresis, protein blotting and immunostaining. 2. 2. All species have a 30,000 to 35,000 mol. wt protein group consisting of multiple isoforms with isoelectric points ranging from pH 4.4 to 5.6. 3. 3. The techniques used in this study have resolved three component subgroups within the 35 K group. 4. 4. A group of proteins at 60,000-65,000 mol. wt has also been consistently identified. 5. 5. We conclude that remarkable similarity exists among the major surfactant-associated proteins from various mammals with regard to isoelectric points, molecular weights and antigenic sites.

Original languageEnglish (US)
Pages (from-to)441-446
Number of pages6
JournalComparative Biochemistry and Physiology -- Part B: Biochemistry and
Volume82
Issue number3
DOIs
StatePublished - Jan 1 1985

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physiology
  • Molecular Biology

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