A Computational method for predicting inferior vena cava filter performance on a patient-specific basis

Kenneth I. Aycock, Robert Lee Campbell, Keefe B. Manning, Shankar P. Sastry, Suzanne M. Shontz, Frank Lynch, Brent A. Craven

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

A computational methodology for simulating virtual inferior vena cava (IVC) filter placement and IVC hemodynamics was developed and demonstrated in two patient-specific IVC geometries: a left-sided IVC and an IVC with a retroaortic left renal vein. An inverse analysis was performed to obtain the approximate in vivo stress state for each patient vein using nonlinear finite element analysis (FEA). Contact modeling was then used to simulate IVC filter placement. Contact area, contact normal force, and maximum vein displacements were higher in the retroaortic IVC than in the left-sided IVC (144 mm2, 0.47N, and 1.49mm versus 68 mm2, 0.22N, and 1.01mm, respectively). Hemodynamics were simulated using computational fluid dynamics (CFD), with four cases for each patient-specific vein: (1) IVC only, (2) IVC with a placed filter, (3) IVC with a placed filter and model embolus, all at resting flow conditions, and (4) IVC with a placed filter and model embolus at exercise flow conditions. Significant hemodynamic differences were observed between the two patient IVCs, with the development of a right-sided jet, larger flow recirculation regions, and lower maximum flow velocities in the left-sided IVC. These results support further investigation of IVC filter placement and hemodynamics on a patient-specific basis.

Original languageEnglish (US)
Article number081003
JournalJournal of Biomechanical Engineering
Volume136
Issue number8
DOIs
StatePublished - Jan 1 2014

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Vena Cava Filters
Hemodynamics
Inferior Vena Cava
Computational methods
Veins
Flow velocity
Computational fluid dynamics
Embolism
Finite element method
Geometry
Finite Element Analysis
Renal Veins
Hydrodynamics
Exercise

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Physiology (medical)

Cite this

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title = "A Computational method for predicting inferior vena cava filter performance on a patient-specific basis",
abstract = "A computational methodology for simulating virtual inferior vena cava (IVC) filter placement and IVC hemodynamics was developed and demonstrated in two patient-specific IVC geometries: a left-sided IVC and an IVC with a retroaortic left renal vein. An inverse analysis was performed to obtain the approximate in vivo stress state for each patient vein using nonlinear finite element analysis (FEA). Contact modeling was then used to simulate IVC filter placement. Contact area, contact normal force, and maximum vein displacements were higher in the retroaortic IVC than in the left-sided IVC (144 mm2, 0.47N, and 1.49mm versus 68 mm2, 0.22N, and 1.01mm, respectively). Hemodynamics were simulated using computational fluid dynamics (CFD), with four cases for each patient-specific vein: (1) IVC only, (2) IVC with a placed filter, (3) IVC with a placed filter and model embolus, all at resting flow conditions, and (4) IVC with a placed filter and model embolus at exercise flow conditions. Significant hemodynamic differences were observed between the two patient IVCs, with the development of a right-sided jet, larger flow recirculation regions, and lower maximum flow velocities in the left-sided IVC. These results support further investigation of IVC filter placement and hemodynamics on a patient-specific basis.",
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A Computational method for predicting inferior vena cava filter performance on a patient-specific basis. / Aycock, Kenneth I.; Campbell, Robert Lee; Manning, Keefe B.; Sastry, Shankar P.; Shontz, Suzanne M.; Lynch, Frank; Craven, Brent A.

In: Journal of Biomechanical Engineering, Vol. 136, No. 8, 081003, 01.01.2014.

Research output: Contribution to journalArticle

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